Clinical trials: Endosonography
Childbirth Related Levator Injuries
Evaluation of Levator Injuries Using Transvaginal Endosonography
Prospective studies to date have identified that the levator ani muscle injuries occur in 14-19% of women after vaginal delivery. In none of studies a vaginal examination was performed at the time of delivery.
- Trial name
- ELITE (NCT01310660)
- Where
- United Kingdom
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Croydon University Hospital
Gastroenterology, Lesions
Evaluation of Diagnostic Yield of EUS-Guided Tissue Sampling
All patients will receive standard medical care and no experimental interventions will be performed. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is a well-established procedure commonly used for the…
- Trial name
- NCT02979509
- Testing
- Endoscopic ultrasound- (EUS) guided tissue sampling
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pancreatic Disease
EUS Ductal Evaluation in One Endoscopic Session for the Diagnosis of Exocrine Pancreas Disease
The purpose of this study is, to develop a standard of care protocol using the combination of EUS, ePFT, and sEUS during one endoscopic session (instead of the three separate endoscopic sessions).
- Trial name
- NCT01997476
- Testing
- Combined EUS, e-PFT and sEUS Testing
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Indiana University
Bile Duct Diseases
The Role of Endoscopic Ultrasound in Evaluation of Patients With Indefinite Cause of Bile Duct Dilatation
In the era of diagnostic imaging advances, Bile Duct Dilatation becomes a common incidental finding in patients present with either gastrointestinal symptoms or undergone the imaging study for any other complaints.
- Trial name
- NCT05475964
- Testing
- Endoscopic ultrasound
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HMHamed
Portal Hypertension, Chronic Liver Disease
EUS vs TJ for Liver Biopsy and Portal Pressure Gradient Measurement
This study will directly compare the endoscopic ultrasound guided approach to obtain adequate liver biopsies and portal pressure gradient measurements to the current standard of care which uses the transjugular approach.
- Conditions
- Portal Hypertension, Chronic Liver Disease, Cirrhosis
- Trial name
- NCT05118308
- Testing
- Transjugular hepatic venous pressure gradient measurement with liver biopsy, Endoscopic ultrasound portal pressure gradient measurement with liver biopsy
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pancreas Adenocarcinoma
Circulating Extracellular Exosomal Small RNA as Potential Biomarker for Human Pancreatic Cancer
This study is for the verification of biomarkers for pancreatic cancer treatment using small RNA liquid biopsy, combined with EUS-FNA tissues.
- Trial name
- NCT04636788
- Testing
- Venous sampling
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Pancreatic Cancer
A Multi-center Study on the Efficacy and Safety of AI-assisted Navigation System for Biliopancreatic EUS
Pancreatic cancer is one of the most lethal cancers. Survival rates vary largely depending on the stage at which it is diagnosed. EUS is considered one of the most sensitive modalities for pancreatic cancer detection.
- Trial name
- NCT04892329
- Testing
- Artificial intelligence assistant system
- Where
- 2 sites in China
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Chronic Pancreatitis
Endoscopic Ultrasound (EUS) Features of Chronic Pancreatitis
The purpose of this study is to correlate Endoscopic Ultrasound (EUS) criteria for chronic pancreatitis with surgical pathology.
- Trial name
- NCT01442454
- Testing
- chronic pancreatitis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gastric Varices
Dermabond Treatment for Gastric Variceal Bleeding
The purpose of having a database is to collect data related to endoscopic ultrasound procedures performed by Indiana University EUS physicians; specifically, for the treatment of gastric variceal bleeding This data will be used…
- Trial name
- NCT02037659
- Testing
- DermaBond treatment of Gastric Varices
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Indiana University
Chronic Pancreatitis
Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis
Physicians need a tracking system for specific treatment modalities, and data to determine the impact of endoscopic ultrasound pain management for patients with chronic pancreatitis.
- Trial name
- CPN (NCT04403074)
- Testing
- Celiac Plexus Neurolysis
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Indiana University
Diagnoses Diseases, Ultrasound Therapy; Complications
19 Versus 22-Gauge Needle for EUS-LB
Chronic liver disorders (CLD) are a major cause of morbidity and mortality for individuals in the US. Though serologic analysis will often lead to a conclusive diagnosis, liver biopsy remains an important method for helping to…
- Conditions
- Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
- Trial name
- EUSLB1922 (NCT02967991)
- Testing
- EUS-guided liver biopsy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Liver Biopsy
Liver Biopsy Using a 19 Gauge Fine Needle Biopsy Needle
A 19 gauge FNB needle, using same technique as with 22 gauge needle, to obtain liver histological specimen in regards to core length and the number of Complete Portal Triads.
- Trial name
- NCT03910790
- Testing
- 19 gauge needle liver biopsy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- AdventHealth
Pancreatic Cancer, Pancreatic Neoplasms
Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography for Malignant Distal Biliary Obstruction
The purpose of this study is to compare the rates of adverse events between patients undergoing Endoscopic Ultrasound- guided biliary drainage and Endoscopic Retrograde Cholangiopancreatography for distal malignant biliary…
- Conditions
- Pancreatic Cancer, Pancreatic Neoplasms, Pancreatic Adenocarcinoma
- Trial name
- NCT03054987
- Testing
- EUS-BD, ERCP
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Alcoholism, Cirrhosis
Acoustic Liver Biopsy in Normals and in Patients With Cirrhosis Using Endoscopic Ultrasound
The purpose of this study is to determine the amount of fibrosis in the liver of hepatitis C patients with advanced fibrosis, using endoscopic ultrasound.
- Conditions
- Alcoholism, Cirrhosis, Hepatitis c
- Trial name
- NCT01208311
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Efficacy, Self
Diagnostic Efficacy Of 3 EUS-FNB Techniques
Endoscopic ultrasound (EUS) is a widely recognized tool for over 30 years for diagnosing intra-abdominal lesions and gastrointestinal cancers, especially pancreatic neoplasia.
- Trial name
- NCT05825729
- Testing
- Dry suction technique (A), Slow-pull technique (B), Wet suction technique (C)
- Where
- 2 sites in Spain
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Insular Gran Canaria
Pancreatic Adenocarcinoma Non-resectable
EUS-RFA for Unresectable Pancreatic Ductal Adenocarcinoma
the study evaluate the efficacy and safety of EUS-RFA using Habib EUS-RFA catheter with a prospective randomised trial in patients with inoperable PDAC.
- Trial name
- NCT03772756
- Testing
- Endoscopic ultrasound guided radiofrequency ablation, chemoradiotherapy
- Where
- 2 sites in China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Liver Diseases, Liver Fibrosis
Prospective Single Centre Observational Study to Compare the Diagnostic Yield of Different Modalities of Liver Biopsy
The goal of this study is to learn about endoscopic ultrasound(EUS) guided liver biopsy and how this compares to traditional methods of obtaining liver biopsy samples, in patients with liver disease.
- Trial name
- NCT05912179
- Testing
- Liver biopsy - percutaneous, Liver biopsy - transjugular, liver biopsy - EUS guided
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Pancreatic Neuroendocrine Tumors, WHO Grade I-II
Endoscopic Ultrasound Guided Radio Frequency Ablation of Pancreatic Neuroendocrine Neoplasms
A national multicenter prospective study to investigate the feasibility and efficacy of endoscopic ultrasound guided radiofrequency ablation of neuroendocrine pancreatic tumors, WHO Grade 1-2 of 3 cm or less in diameter.
- Trial name
- ERFA-PNET (NCT05243082)
- Testing
- Radio frequency ablation
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Endoscopic Ultrasound (EUS), Solid Pancreatic Lesion
An Artificial Intelligence System for Multimodal, Multi-class Diagnosing Solid Pancreatic Lesions Based on Endoscopic Ultrasound
The aim of this study is to validate an artificial intelligence system named iEUS-SPL(intelligent endoscopic ultrasound system-solid pancreatic lesion) for detecting and multimodal, multi-class diagnosing solid pancreatic lesions…
- Trial name
- NCT07381192
- Testing
- iEUS-SPL(intelligent endoscopic ultrasound system-pancreatic solid lesion)
- Where
- China
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Cirrhosis, Compensated Cirrhosis
The Use of Endoscopic Ultrasound-Guided Portal Pressure Measurements to Guide Beta-Blocker Therapy in Patients With Compensated Cirrhosis
This pilot study to determine the feasibility of EUS-Portal Pressure Measurements to guide Beta-Blocker Therapy in patients with compensated cirrhosis .The study will be a prospective tandem controlled trial consisting of 30…
- Conditions
- Cirrhosis, Compensated Cirrhosis, Portal Hypertension
- Trial name
- NCT05357599
- Testing
- EUS
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southern California