Clinical trials: Endovascular Aortic Repair
Fenestrated Endovascular Aortic Repair
Changes in Renal Artery Movement Due to Respiration Before and After Fenestrated Endovascular Repair
Purpose: The purpose of this study is to evaluate the location within the renal artery of maximal angular displacement before and after fenestrated endovascular aortic repair (FEVAR) using CT with end-inspiration and…
- Trial name
- NCT02266862
- Testing
- Study group
- Sponsor
- University of North Carolina, Chapel Hill
Intraprosthetic Thrombus, Limb Graft Occlusion
Computational Fluid Dynamics Predicting Intraprosthetic Thrombus Formation and Progression Following EVAR
Intraprosthetic thrombus (IPT) formation and its progression to limb graft occlusion (LGO) are significant complications following endovascular aneurysm repair (EVAR).
- Trial name
- NCT06701773
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Abdominal Aortic Aneurysm
Percutaneous Endovascular Aneurysm Repair (PEVAR) Trial
To determine the safety and effectiveness of PEVAR.
- Trial name
- PEVAR (NCT01070069)
- Testing
- PEVAR (ProGlide closure), SEVAR (IntuiTrak), PEVAR (Prostar XL closure)
- Where
- 20 sites in United States
- Volunteers
- 192 people
- Sponsor
- Endologix
Juxtarenal Aortic Aneurysm, Pararenal Aneurysm
Comparison of Outcomes of Complex Abdominal Aortic Aneurysm Treatment
Background: Open repair remains the gold standard for fit patients with complex AAA. In the past decade, an evolution of devices, design, components, and delivery systems expanded the application of EVAR in these challenging…
- Trial name
- NCT04773223
- Testing
- Open surgery and complex EVAR due to AAA
- Where
- Serbia
- Volunteers
- 925 people
- Sponsor
- Clinical Centre of Serbia
Thoracoabdominal Aortic Aneurysm, Endovascular Repair
Clinical Trial of BAO-G Technique in Complex Aortic Aneurysm Endovascular Repair (BAO-G-02)
Multi-Branch AOrtic Reconstruction With G-iliac System (BAO-G) Technique is a novel technique of endovascular repair of complex aortic aneurysm, which using off-the-shelf iliac branched devices to reconstruct the visceral…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Endovascular Repair, Complex Aortic Aneurysms
- Trial name
- BAO-G-02 (NCT07141251)
- Testing
- BAO-G
- Where
- 11 sites in China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Safety and Performance of the Nellix Endovascular Sealing System
Nellix® Registry Study: EVAS-Global
This registry has been designed as a multicenter, single arm, open label, post-market registry study with consecutive, eligible patient enrollment at each site.
- Trial name
- EVAS-FORWARD 1 (NCT02018744)
- Where
- 19 sites in Germany, Latvia and 6 more
- Volunteers
- 300 people
- Sponsor
- Endologix
Aortic Aneurysm, Aortic Aneurysm Abdominal
Evaluation of the iCover Stent as a Bridging Stent in Fenestrated Endovascular Aneurysm Repair (fEVAR) for Complex Aortic Aneurysms.
ReiCo is a French retrospective, multicenter, single-arm study focused on assessing the safety and clinical performance of the iCover balloon-expandable covered stent (iVascular) when implanted as a bridging stent during fEVAR…
- Trial name
- ReiCo (NCT07742254)
- Where
- 3 sites in France
- Volunteers
- 154 people
- Sponsor
- iVascular S.L.U.
Aortic Aneurysm, Aortic Aneurysm, Abdominal
Safety and Efficacy of Multiple Overlapping Uncovered Stents for Pararenal Aortic Aneurysm Repair
Complex aortic aneurysms involving major branches have been difficult endovascularly. The primary purposes of this study is to evaluate the safety, feasibility, and efficacy of multiple overlapping uncovered stents in treating…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracic, Aortic Aneurysm, Thoracoabdominal
- Trial name
- SEMPER (NCT01985906)
- Testing
- Multiple overlapping uncovered stents, Uncovered stents
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
Juxtarenal Aortic Aneurysm
Endovascular Repair of Juxtarenal Aortic Aneurysm
The investigators compare different endovascular techniques as an alternative to surgical reconstruction to repair JAAS regarding ; success rates, 30-day mortality,endoleak events secondary intervention rates
- Trial name
- NCT04252079
- Testing
- Endovascular Repair of Juxtarenal Aortic Aneurysm
- Volunteers
- 30 people
- Sponsor
- Assiut University
Abdominal Aortic Aneurysm
3D Ultrasound of Abdominal Aortic Aneurysm Characteristics
AAA characteristics are traditionally measured with computed tomography angiography (CTA), however, three-dimensional ultrasound (3D US) is emerging as a novel imaging method for AAAs.
- Trial name
- 3D US - EVAR (NCT05871515)
- Testing
- 3D ultrasound
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Type II Endoleak, Abdominal Aortic Aneurysm Enlargement
Deep-learning Predictors of Abdominal Aortic Aneurysm Enlargement in Type II Endoleaks After Endovascular Aortic Repair: The RADAR Study
Background and rationale: Abdominal aortic aneurysm (AAA) is a weakening and enlargement of the main artery in the abdomen. Endovascular aneurysm repair (EVAR) is a minimally invasive treatment used to repair an AAA.
- Trial name
- RADAR (NCT07783126)
- Testing
- Artificial intelligence model analyzing preoperative CT angiography
- Volunteers
- 1,250 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Postimplantation Syndrome, Myocardial Injury
Steroid Treatment to Prevent Thoracic Endovascular Aortic Repair Postimplantation Syndrome
Postimplantation syndrome (PIS) is a common and clinically important complication following thoracic endovascular aortic repair (TEVAR).
- Conditions
- Postimplantation Syndrome, Myocardial Injury, MACE, Mortality
- Trial name
- STOP TEVAR PIS (NCT07328906)
- Testing
- Methylprednisolone (MP)
- Where
- Serbia
- Volunteers
- 174 people
- Sponsor
- University of Belgrade
AKI
Protection From Acute Kidney Injury (AKI) With Basis™ Treatment
This study is a single-center, prospective, randomized, double-blinded, placebo-controlled phase II clinical trial to evaluate the efficacy of "NAD+ supplementation" with Basis™ (Nicotinamide Riboside and Pterostilbene) in…
- Trial name
- NCT04342975
- Testing
- Nicotinamide Riboside + Pterostilbene
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Abdominal Aortic Aneurysm (AAA)
Image Fusion of Preprocedural CTA With Real Time Fluoroscopy to Enhance EVAR Repair
Abdominal Aortic Aneurysm (AAA) is a potentially life threatening condition. If the aneurysm ruptures, the mortality can be as high as 80%.
- Trial name
- NCT02295137
- Testing
- Using pre-procedural CTA to guide advanced EVAR procedure
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Aortic Aneurysm, Thoracic, Chronic Type B Dissection
Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Descending TAA and Chronic Dissections
The purpose of the Feasibility study is to characterize the safety of the Valiant Mona LSA Thoracic Stent Graft System, including an assessment of the safety and effectiveness of the device acutely and at the 30 day visit in the…
- Trial name
- NCT02365467
- Testing
- Valiant Mona LSA Thoracic Stent Graft System
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medtronic Cardiovascular
Abdominal Aortic Aneurysm, Iliac Aneurysm
Global Iliac Branch Study
This project seeks to determine if certain anatomic factors, specifically tortuous and non-conformable iliac arteries, may predict device complications, including seal zone failure, type III endoleak, and occlusion.
- Trial name
- GIBS (NCT05607277)
- Testing
- Endovascular Repair of abdominal aortic aneurysms
- Where
- United States
- Volunteers
- 297 people
- Sponsor
- University of Wisconsin, Madison
Postimplantation Syndrome, Endovascular Abdominal Aortic Aneurysm Repair (EVAR)
Post-Implantation Syndrome and Laboratory Markers Following EVAR and TEVAR
The aim of this observational study is to investigate the relationship between postimplantation syndrome (PIS) and laboratory inflammatory parameters following endovascular aortic repair (EVAR/TEVAR).
- Conditions
- Postimplantation Syndrome, Endovascular Abdominal Aortic Aneurysm Repair (EVAR), Thoracic Endovascular Aortic Repair
- Trial name
- PIS and EVAR (NCT07014839)
- Testing
- Endovascular Aortic Intervention
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ataturk University
Aortic Dissection
Prospective Study of Tailored Management Strategies for Malperfusion Syndrome
Management strategy of malperfusion syndrome in acute type A aortic dissection (ATAAD) patients remains controversial, with different views on when the surgery should be offered.
- Trial name
- NCT05517356
- Testing
- Tailored management strategies
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xiamen Cardiovascular Hospital, Xiamen University
Aorta Aneurysm
Graft Thrombosis After Endovascular Aortic Repair - a Single Center Experience With the Cook Zenith Alpha Spiral-Z®
The purpose of this study is to assess the extent of thrombosis in the Zenith Alpha Spiral-Z® stent graft.
- Trial name
- NCT04564560
- Testing
- Endovascular aortic repair with Zenith Alpha Spiral-Z®
- Where
- Norway
- Volunteers
- 161 people
- Sponsor
- St. Olavs Hospital
Residual Dissection After Repair for Type A Aortic Dissection
Effectiveness and Safety of a Type A Dissection Total Endovascular Reconstruction System in Promoting Favorable Distal Aortic Remodeling
This is a prospective, multicenter, randomized controlled clinical study. A total of 198 eligible subjects will be enrolled and randomly assigned in a 1:1 ratio to either the Study Group or the Control Group.
- Trial name
- REFORM-TAD (NCT07402252)
- Testing
- surgical treatment, Standard of Care (Investigator Choice)
- Where
- China
- Volunteers
- 198 people
- Sponsor
- West China Hospital