Clinical trials: Endovascular Thrombectomy
Intracranial Aneurysm, Intracranial Aneurysm, Wide Neck Aneurysm, Large Neck Aneurysm Lesion
Microvention AnEurysm & STroke Real-life Data cOllection
The MAESTRO registry is a post-market, single-arm, non-interventional, multicenter registry
- Conditions
- Intracranial Aneurysm, Intracranial Aneurysm, Wide Neck Aneurysm, Large Neck Aneurysm Lesion, Aneurysmal Subarachnoid Hemorrhage, Ischemic Stroke
- Trial name
- MAESTRO (NCT06494436)
- Testing
- All Microvention Class III implantable device CE marked, All Microvention Mechanical Thrombectomy Class III device CE marked
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Microvention-Terumo, Inc.
Ischemic Stroke, Large Vessel Occlusion
Combination of Hypothermia and Thrombectomy in Acute Stroke
The goal of this clinical trial is to test the combination of hypothermia and endovascular treatment in acute stroke patients with large vessel occlusion.
- Conditions
- Ischemic Stroke, Large Vessel Occlusion, Endovascular Treatment
- Trial name
- COTTIS-2 (NCT06301412)
- Testing
- hypothermia
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- University of Freiburg
Stroke, Acute Ischemic Stroke
The MRI-based Evaluation of Safety and Efficacy of EVT and SMT: A Retrospective, Multicenter Study
Acute Basilar Artery Occlusion (ABAO), a condition with a high risk of mortality or disability (up to 80%). The safety and efficacy of endovascular thrombectomy (EVT) in ABAO remains uncertain due to inconsistent evidence from…
- Conditions
- Stroke, Acute Ischemic Stroke, Ischemic Stroke
- Trial name
- NCT06236828
- Testing
- Mechanical Thrombectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Arterial Ischemic Stroke
National Retrospective Study Of Recanalization Treatments In Pediatric Arterial Ischemic Stroke
The purpose of this study is to evaluate recanalization treatments use, safety and efficacy at the acute phase of arterial ischemic stroke in pediatric patients
- Trial name
- KID-CLOT (NCT03887143)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sinus Thrombosis, Intracranial
Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis
Background: Endovascular thrombolysis, with or without mechanical clot removal (ET), may be beneficial for a subgroup of patients with cerebral venous sinus thrombosis (CVT), who have a poor prognosis despite treatment with…
- Trial name
- TOACT (NCT01204333)
- Testing
- Endovascular thrombolysis, Heparin
- Where
- 15 sites in Canada, China and 4 more
- Volunteers
- 67 people
- Sponsor
- Jan Stam, MD, PhD
Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation
Screening of Endovascular Thrombectomy With MRI in Acute Ischemic Stroke
The goal of this observational study is to learn about the role of MRI evaluation based on FVH-DWI mismatch principle in preoperative evaluation of endovascular thrombolectomy.
- Conditions
- Fluid-attenuated Inversion Recovery Sequence Vascular Hyperintensity-diffusion-weighted Imaging Mismatch(FVH-DWI Mismatch), Image Evaluation, Endovascular Thrombectomy
- Trial name
- NCT06213870
- Testing
- Surgical criteria
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Tianjin Huanhu Hospital
Stroke, Ischemic, Anesthesia
Anaesthesia for Mechanical Thrombectomy
Title: Conduct of anaesthesia during acute ischaemic stroke: a retrospective case series of patients undergoing mechanical thrombectomy. Design: This study will be a retrospective consecutive observational case series
- Trial name
- NCT04804085
- Volunteers
- 250 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Hemodynamic Stability, Ischemic Strokes
Ciprofol vs Propofol for Hemodynamic Stability in Patients Having General Anesthesia for Endovascular Thrombectomy After Ischemic Stroke
Endovascular therapy (EVT) improves the prognosis of patients with acute ischemic stroke (AIS). EVT has been established as a standard of care for AIS caused with large vessel occlusion based on numerous randomized controlled…
- Trial name
- NCT07696208
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 124 people
- Sponsor
- RenJi Hospital
Stroke, Acute, Carotid Stenosis
Endovascular Acute Stroke Intervention - Tandem OCclusion Trial
Patients with tandem occlusion or tandem lesion (TL), that is, stroke with an acute intracranial anterior circulation occlusion and an ipsilateral cervical ICA (c-ICA) high-grade stenosis or occlusion, constitute about 15-20% of…
- Conditions
- Stroke, Acute, Carotid Stenosis, Carotid Artery Diseases
- Trial name
- EASI-TOC (NCT04261478)
- Testing
- Carotid artery stenting, Antiplatelet Agents
- Where
- Canada
- Volunteers
- 458 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Stroke, Acute
Endovascular Acute Stroke Intervention Trial - the EASI Trial
Stroke constitutes the primary cause of acquired disability in adults and the second cause of dementia following Alzheimer disease.
- Trial name
- EASI (NCT02157532)
- Testing
- mechanical thrombectomy, Best standard treatment
- Where
- 2 sites in Canada
- Volunteers
- 480 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Acute Ischemic Stroke
Kanagawa Intravenous and Endvascular Treatment Registry
The K-NET registry is a prospective, multicenter, observational registry study for all consecutive patients who received intravenous tPA therapy and/or endovascular treatment for acute ischemic stroke.
- Trial name
- K-NET (NCT05213533)
- Where
- Japan
- Volunteers
- 4,000 people
- Sponsor
- St. Marianna University Toyoko Hospital
Ischemic Stroke, Stroke
Australasian Nanoparticle-mediated Magnetically Enhanced Diffusion for Ischemic Stroke
Rapidly restoring blood flow to the brain in patients with stroke caused by a blocked blood vessel in the brain is the key to reducing disability.
- Trial name
- AusNanoMED (NCT06495671)
- Testing
- Magnetically enhanced diffusion
- Where
- 7 sites in Australia
- Volunteers
- 30 people
- Sponsor
- University of Melbourne
Acute Ischemic Stroke
Biomarkers to Predict Hemorrhage and Outcomes After Endovascular Treatment in Patients With Acute Large Vessel Occlusion
The main aim of the biomarkers to predict Hemorrhagic transformation(HT) after endovascular treatment in Acute Ischemic Stroke Patients. The study has three main parts.
- Trial name
- NCT03915834
- Testing
- Endovascular treatment
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- Capital Medical University
Stroke of Basilar Artery, Optical Coherence Tomography
Optical Coherence Tomography Guided Antithrombotic Treatment After Endovascular Thrombectomy of the Posterior Circulation
Evidence regarding the role of early (<24 hours) antithrombotics post-revascularization with either intravenous thrombolysis (IVT), endovascular thrombectomy (EVT), or a combination of both remains scarce.
- Conditions
- Stroke of Basilar Artery, Optical Coherence Tomography, Antithrombotics, Endovascular Thrombectomy
- Trial name
- NCT04121611
- Testing
- Unfractionated heparin, Acetylsalicylic Acid (ASA)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Sunnybrook Health Sciences Centre
Ischemic Stroke
Glucagon-like Peptide-1 Receptor Agonists for Endovascular Stroke Thrombectomy
Endovascular thrombectomy (EVT) is a procedure that improves recovery for people who suffer from a stroke by removing blood clots from large blood vessels in the brain.
- Trial name
- LEAST (NCT07511543)
- Testing
- Semaglutide
- Volunteers
- 100 people
- Sponsor
- Population Health Research Institute
Stroke, Acute Ischemic
Intra-Arterial Thrombolysis After SUCCESSful Reperfusion in Anterior Circulation Ischemic Stroke
Stroke is a leading cause of disability and mortality worldwide. Despite the clinical benefit of mechanical thrombectomy, 1 out of 2 patients treated are functionally independent at 90 days.
- Trial name
- IA-SUCCESS (NCT06768138)
- Testing
- Intra-arterial infusion of Alteplase
- Where
- France
- Volunteers
- 626 people
- Sponsor
- Central Hospital, Nancy, France
Acute Ischemic Stroke
PROMISE: PRedictors Of Good outcoMes in Thrombectomy for Large Infarct Core Stroke Evaluation
Identify the factors associated with a favorable clinical outcome in participants with acute ischemic stroke and large core infarcts within 24 hours of onset who are treated with endovascular intervention.
- Trial name
- NCT06016348
- Testing
- Endovascular treatment
- Where
- 4 sites in Vietnam
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- 115 People's Hospital
Acute Ischemic Stroke
A Prospective, Trial About Safety and Efficacy of Combined Treatment With Cerebrolysin in Acute Ischemic Hemispheric Stroke Patients Undergoing EndoVascular Treatment (EVT)
The goal of this clinical trial is investigate the efficacy of a neuro/vascular-protective treatment with the drug Cerebrolysin in patients with acute ischemic stroke. starting immediately after completion of a EVT therapy.
- Trial name
- NCT06070753
- Testing
- Cerebrolysin
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Shaare Zedek Medical Center
Stroke, Acute
Carotid Duplex Ultrasound for Selecting Patients for Endovascular Thrombectomy in Acute Stroke Patients
The aim of this study is to address the usefulness of carotid duplex ultrasound as vascular imaging for selecting acute stroke patients for endovascular thrombectomy.
- Trial name
- ECHO-SELECT (NCT02989376)
- Testing
- After detection of occluded vessels by vascular imaging using carotid duplex ultrasound, digital subtraction angiography is immediately performed before acute endovascular treatment.
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Ryo Itabashi
Acute Ischemic Stroke
German Stroke Registry - Endovascular Treatment
The German Stroke Registry (GSR) Endovascular Treatment is an academic, independent, prospective, multicentre, observational registry study.
- Trial name
- GSR-ET (NCT03356392)
- Testing
- telephone call d90
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf