Clinical trials: Endovascular Treatment
Submassive Pulmonary Embolism
Long Term Effects of Treating Submassive Pulmonary Embolism With Ultra-sound Accelerated Thrombolysis
Patients with Submassive Pulmonary Embolism treated with ultra-sound therapy will have an improved right ventricular function 72 hours post treatment.
- Trial name
- SPEAR (NCT01899339)
- Testing
- submassive PA treatment with Ekosonic endo device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Corewell Health West
Venous Reflux
ClosureFAST - Radiofrequency Great Saphenous Vein Treatment
The purpose of this study is to confirm that the ClosureFAST system can be used as an alternative to the current ClosurePlus catheter for treating the GSV and to accumulate pivotal data for optimization of the operating…
- Trial name
- NCT00842296
- Testing
- RF ablation (ClosureFAST)
- Volunteers
- 326 people
- Sponsor
- Medtronic Endovascular
Stroke, Endovascular Treatment
Normobaric Hyperoxia Combined With Endovascular Treatment for Acute Ischemic Stroke
The purpose of this study is to evaluate the safety and efficiency of normobaric hyperoxia combined with endovascular treatment for acute ischemic stroke patients with stroke onset 6-24 hours.
- Conditions
- Stroke, Endovascular Treatment, Neuroprotection
- Trial name
- NCT05128422
- Testing
- Normobaric oxygen therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Aortic Aneurysms
Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Aortic Aneurysms
The aim of this study is to prospectively compare the perioperative mortality severe morbidity and the costs of endovascular versus conventional surgical repair of pararenal, supra-renal and type 4 THORACO-abdominal aortic…
- Trial name
- Windows1 (NCT01168037)
- Testing
- Endovascular aortic repair with branched/fenestrated stent-graft, Open Surgical Repair
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Peripheral Vascular Disease, Critical Limb Ischemia
Near Infrared Spectroscopy and Transcutaneous Oxygen Pressure in Critical Limb Ischemia Before and After Treatment
Comparison of two non-invasive methods for measuring tissue oxygenation. One is Transcutaneous Oxygen Pressure (TCPO2) and the other is the new method of Near Infrared Spectroscopy (NIRS) - near infrared spectroscopy in patients…
- Trial name
- NIRS (NCT01459341)
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Carmel Medical Center
Aneurysms
A Study to Look at Performance of MICRUSFRAME and GALAXY Coils for the Treatment of Intracranial Aneurysms
A post-market registry evaluating ruptured/unruptured aneurysms treated with MICRUSFRAME and GALAXY coils
- Trial name
- STERLING (NCT03642639)
- Testing
- MICRUSFRAME and GALAXY coils
- Where
- 51 sites in United States, Belgium and 8 more
- Volunteers
- 723 people
- Sponsor
- Cerenovus, Part of DePuy Synthes Products, Inc.
Acute Ischemic Stroke
Study of Endovascular Therapy in Acute Anterior Circulation Large Vessel Occlusive Patients With a Large Infarct Core
Endovascular therapy (EVT) was recommended as the primary treatment for patients with acute large vascular occlusion (LVO) in anterior circulation.
- Trial name
- ANGEL-ASPECT (NCT04551664)
- Testing
- Best medical management, Endovascular therapy
- Where
- China
- Volunteers
- 456 people
- Sponsor
- Beijing Tiantan Hospital
Stroke Inflammation
Fingolimod in Endovascular Treatment of Ischemic Stroke
Proof-of concept clinical trials have indicated that the sphingosine-1-phosphate receptor modulator fingolimod may be efficacious in attenuating brain inflammation and improving clinical outcomes in patients with acute ischemic…
- Trial name
- NCT04629872
- Testing
- Fingolimod
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Ning Wang, MD., PhD.
Limb Salvage Rates With Endovascular Therapy
Endovascular Limb Salvage in Trinidad and Tobago
The purpose of this study was to investigate limb salvage rates in patients with critical limb ischemia after endovascular revascularization.
- Trial name
- NCT05547022
- Testing
- Endovascular revascularisation
- Where
- Trinidad and Tobago
- Volunteers
- 157 people
- Sponsor
- Naveen Seecheran
Complex Abdominal Aortic Aneurysm, ie. Juxtarenal or Suprarenal Aortic Aneurysms, Treated by Fenestrated Endovascular Aortic Aneurysm Repair or Open Repair
Cost-utility Analysis of Fenestrated Aortic Stents Versus Open Surgery for the Treatment of Complex Abdominal Aortic Aneurysms
Introduction: Complex abdominal aortic aneurysms (CAA) are defined as abdominal aneurysms that are anatomically unsuitable for a standard endovascular repair because of a short infrarenal neck or no infrarenal neck.
- Trial name
- ORFEVAR (NCT04671732)
- Testing
- Fenestrated endovascular aortic aneurysm repair, open repair of abdominal aortic aneurysm.
- Where
- France
- Volunteers
- 492 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Acute, Ischemic Stroke, Acute
Endovascular Therapy for Large Core Patients With Uncertain Response to Thrombectomy
The purpose of this study is to assess the safety and efficacy of endovascular thrombectomy in both an early and extended time window in patients with large strokes due to large artery occlusion.
- Trial name
- OUTER LIMITS (NCT06961487)
- Testing
- EndovascularThrombectomy, Endovascular thrombectomy with any FDA-approved device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Endovascular Therapy, Brain Edema
Early Identification of Malignant Brain Edema in laRge Artery oCclusive Stroke After Endovascular Therapy (EMBRACE Study)
To design and validate a predictive model for malignant brain edema after endovascular thrombectomy.
- Conditions
- Endovascular Therapy, Brain Edema, Prediction Model, Ischemic Stroke
- Trial name
- EMBRACE (NCT06451887)
- Where
- China
- Volunteers
- 1,950 people
- Sponsor
- Zhejiang Provincial People's Hospital
Posterior Circulation Brain Infarction
Choice of Anesthesia for Endovascular Treatment of Acute Ischemic Stroke in Posterior Circulation
There is few randomized controlled clinical to investigated the impact of anesthetic type on outcome in patients with acute ischemic stroke in posterior cerebral circulation.
- Trial name
- CANVAS-II (NCT03317535)
- Testing
- General anesthesia, Local anesthesia/concious sedation, Spontaneous breath
- Where
- 2 sites in China
- Volunteers
- 93 people
- Sponsor
- Beijing Tiantan Hospital
Cerebral Venous Sinus Thrombosis
The Dedicated Venous Sinus Thrombectomy Stent for Endovascular Treatment of Cerebral Venous Sinus Thrombosis.
A prospective, single-center, open-label,randomized, controlled,non-inferiority clinical trial will be conducted to evaluate the safety and efficacy of a dedicated venous sinus thrombectomy stent for endovascular treatment of…
- Trial name
- NCT05291585
- Testing
- the dedicated venous sinus thrombectomy stent, balloon catheter thrombectomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ji Xunming,MD,PhD
Stroke, Stroke, Acute
BELgian CT-perFUSion Study to Select Acute Stroke Patients for Thrombectomy
The goal of this clinical trial is to test whether perfusion CT can be used as a selection tool in stroke patients with a major anterior circulation occlusion, to exclude patients from thrombectomy because of a predicted…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- BELFUS (NCT05685043)
- Testing
- perfusion CT
- Sponsor
- University Hospital, Ghent
Complex Abdominal Aortic Aneurysm
Compassionate Use Treatment for a Single Patient With a Custom Made Branched/Fenestrated Endovascular Device for the Treatment of Complex Abdominal Aortic Aneurysm
The FENESTRATED AAA ENDOVASCULAR GRAFT WITH THE H\&L-B ONE-SHOT™ INTRODUCTION SYSTEM is neither commercially available or available as part of a clinical trial.
- Trial name
- NCT03159858
- Testing
- Fenerated AAA Endovascular Graft with H&L-B One Shot Introduction System
- Where
- United States
- Sponsor
- NYU Langone Health
Ischemic Stroke, Blood Pressure
Blood PREssure Augmentation in Large-vessel Occlusion Stroke Study
An open label, prospective, single center, pilot trial to assess feasibility and tolerability of short term blood pressure augmentation to minimize infarct progression in acute LVO stroke patients undergoing endovascular therapy.
- Trial name
- PRESS (NCT04218773)
- Testing
- Phenylephrine, Norepinephrine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Abdominal Aortic Aneurysms
Physician Modified Endovascular Grafts
The primary objectives of this study are to determine whether physician modified endovascular grafts (PMEG) and specified company manufactured investigational devices are a safe and effective method of treating patients with…
- Trial name
- PMEG (NCT01538056)
- Testing
- Fenestrated Endovascular Graft or Company Manufactured Terumo Aortic Fenestrated TREO Endovascular Graft
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Washington
Carotid Artery Aneurysm
Carotid Artery Aneurysm Treatment Using CGuard Divert-And-Heal Strategy
Non-randomized, single arm, open label, academic observational study of CGuard MicroNet covered stent system use to achieve endovascular lumen reconstruction in carotid artery aneurysms with indications for treatment (enlarging…
- Trial name
- C-HEAL (NCT04434456)
- Testing
- CGuard stent implantation
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- John Paul II Hospital, Krakow
Abdominal Aortic Aneurysm
DynaCT Imaging in EVAR: Comparing Clinical Benefit of DynaCT to Multidetector CT as the Current Gold Standard.
The aim of this study is to evaluate a new way to create CT-like images during intra-operative procedures. We want to prove that the quality and information received from DynaCT is satisfactory in implementing stent-graft in…
- Trial name
- NCT00264862
- Testing
- DynaCT
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Norwegian University of Science and Technology