Clinical trials: Endovascular Treatments
Pulsatile Tinnitus
Dural Sinus Stenting of Low Grade Dural Arteriovenous Fistulae (DAVF) for Pulsatile Tinnitus Treatment
The goal of this randomized trial to assess the angiographic efficacy of venous stenting in dural arteriovenous fistulae (DAVF) via improvment on Cognard's Classification as compared to no intervention at 6 months Participants…
- Trial name
- INVENT (NCT05679271)
- Testing
- Venous stenting, Standard of care
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Bordeaux
Critical Limb Ischemia
Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia
This study will compare the effectiveness of best available surgical treatment with best available endovascular treatment in adults with critical limb ischemia (CLI) who are eligible for both treatment options.
- Trial name
- BEST-CLI (NCT02060630)
- Testing
- Open surgical revascularization, Endovascular revascularization
- Where
- 161 sites in United States, Canada and 3 more
- Volunteers
- 1,843 people
- Sponsor
- Carelon Research
Acute Ischemic Stroke
Rescue Distal Thrombectomy in Treatment for Persistent Distal Occlusions
The goal of this clinical trial is to determine whether rescue distal mechanical thrombectomy can improve outcomes in patients with persistent distal occlusions after successful proximal mechanical thrombectomy for acute ischemic…
- Trial name
- 2BE3-PhaseII (NCT07533253)
- Testing
- Proximal mechanical thrombectomy, Rescue distal mechanical thrombectomy, Conservative management
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Acute Ischemic Stroke
Efficacy and Safety of Human Urinary Kallidinogenase Combined With Endovascular Therapy in Acute Ischemic Stroke With Large Vessel Occlusion
The purpose of this study is to evaluate the safety and efficacy of Human Urinary Kallidinogenase combined with endovascular therapy in acute ischemic stroke (AIS) patients with large vessel occlusion.
- Trial name
- HEAL (NCT06211712)
- Testing
- Experimental: Human Urinary Kallidinogenase
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huashan Hospital
Erectile Dysfunction
Endovascular Therapy for Erectile Dysfunction
Brief Summary: Background and pathophysiology Erectile dysfunction is a serious disease with a significant impact on the quality of life.
- Trial name
- RE-ACTION (NCT04333173)
- Testing
- endovascular procedure
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Clinica San Gaudenzio
Acute Ischemic Stroke
Albumin for Patients With Acute Large Vessel Occlusive Stroke Undergoing Endovascular Reperfusion Therapy
The objective of this study is to evaluate the effectiveness and safety of endovascular therapy combined with 25% human albumin in the treatment of acute large vessel occlusive stroke.
- Trial name
- NCT06538844
- Testing
- Intravenous infusion of human albumin, Saline
- Where
- 8 sites in China
- Volunteers
- 134 people
- Sponsor
- Capital Medical University
Ischemic Stroke
Reperfusion Injury After Endovascular Stroke Treatment
Endovascular stroke treatment with mechanical thrombectomy (MT) has become the standard therapy for intracranial large vessel occlusion (LVO).
- Trial name
- DYNASTROKE (NCT05273216)
- Testing
- Transcranial Duplex Sonography, Brain MRI, Blood biomarkers
- Where
- 3 sites in Austria
- Volunteers
- 600 people
- Sponsor
- Medical University of Graz
Stroke, Stroke Acute
Mechanical Thrombectomy in the Middle East and North Africa: Interim Results from the MEMENTO Registry
The MEMENTO (MEchanical thrMobectomy NETwork for MENA TOgether) Registry is a multicenter, prospective observational study aiming to evaluate the effectiveness, safety, and cost-effectiveness of mechanical thrombectomy (MT) in…
- Conditions
- Stroke, Stroke Acute, Endovascular Procedures, Large Vessel Occlusion
- Trial name
- MEMENTO Regist (NCT06702787)
- Where
- Egypt
- Volunteers
- 1,500 people
- Sponsor
- Middle East North Africa Stroke and Interventional Neurotherapies Organization
Stenosis of Artery, Peripheral Arterial Disease
The Merit WRAPSODY™ Endovascular Stent Graft for Treatment of Iliac Artery Occlusive Disease
This is a prospective, single-center, non-randomized phase 2, first-in-iliac artery study, to evaluate the safety and effectiveness of the WRAPSODY Stent Graft for the treatment of peripheral arterial occlusive disease in…
- Conditions
- Stenosis of Artery, Peripheral Arterial Disease, Iliac Artery Disease, Iliac Artery Occlusion
- Trial name
- NCT03994185
- Testing
- Placement of WRAPSODY stent graft
- Sponsor
- Merit Medical Systems, Inc.
Venous Stenosis, Venous Occlusion
The Merit WRAPSODY Central Feasibility Study
The purpose of the study is to demonstrate the safety and efficacy of the Merit WRAPSODY Endovascular Stent Graft for treatment of stenosis or occlusion within the dialysis access outflow circuit in the thoracic central veins
- Trial name
- WAVE Central (NCT04541576)
- Testing
- Merit WRAPSODY Endovascular Stent Graft
- Sponsor
- Merit Medical Systems, Inc.
Liver Cancer, Pancreas Cancer
A Clinical Trial to Evaluate Safety and Efficacy of Endovascualr Denervation in Treatment of Cancer Pain
A prospective, multicenter, self-control clinical trial aim to enroll 110 patients suffered from upper abdominal (liver, pancreas, stomach, etc.) cancers .
- Conditions
- Liver Cancer, Pancreas Cancer, Stomach Cancer, Bile Duct Cancer
- Trial name
- NCT04014478
- Testing
- Endovascular Denervation
- Volunteers
- 110 people
- Sponsor
- Shanghai Golden Leaf MedTec Co. Ltd
Aortic Aneurysm, Abdominal, Complication of Surgical Procedure
Myocardial Injury in Treatment of AAA
Comparison of elective infrarenal aneurysm surgery with open and endovascular technique, respectively, for subclinical ischemic myocardial injury detectable with troponin T and/or 3-channel Holter ECG with ST analysis
- Conditions
- Aortic Aneurysm, Abdominal, Complication of Surgical Procedure, Myocardium; Ischemic
- Trial name
- TREATROP (NCT04292652)
- Testing
- AAA surgery
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Göteborg University
Tumor Cells, Circulating, Venous Thrombosis
The Correlation Between Circulatory Tumor Cells and Venous Thrombosis
Research indicates a strong correlation between cancer and thrombosis, with approximately 20% of blood clots in the U.S. being cancer-related, according to CDC data.
- Trial name
- NCT06672250
- Testing
- CTCs/CTMs culture
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Peripheral Vascular Diseases
Individual Patient Data Analysis of Viabahn for Peripheral Arterial Disease
To evaluate the effectiveness of the VSX device in pre-determined patient populations to understand the patient characteristics that impact outcomes.
- Trial name
- Insight-VSX (NCT05459818)
- Testing
- Viabahn implanted
- Where
- Netherlands
- Volunteers
- 977 people
- Sponsor
- Rijnstate Hospital
Efficacy/Long-term Effectiveness Endovascular Therapy in PAD
PTA-Registry, a Prospective, Multicenter Study With 24-Month Follow-up
The PTA-Registry (PTA-REG) is a prospective health services research registry to monitor and follow-up patients with peripheral arterial disease undergoing endovascular peripheral intervention.
- Trial name
- PTAReg (NCT03045224)
- Testing
- PTA, balloon angioplasty, stent
- Volunteers
- 1,760 people
- Sponsor
- Vascular Center Berlin
Unruptured Intracranial Aneurysm, Indobufen
INdobufen Versus asPirin in Endovascular Unruptured Intracranial Aneurysms Treatment (INPUT)
This project aims to evaluate the safety and efficacy of the antiplatelet regimen combining indobufen and clopidogrel in preventing ischemic events after stent-assisted coiling embolization and flow diverter implantation for…
- Trial name
- NCT07089862
- Testing
- Indobufen treatment, Aspirin treatment
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- Beijing Tiantan Hospital
Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Cerebral
The Effect of Transcutaneous Vagal Nerve Stimulation (tVNS) on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage
The significance of developing a safe and effective therapy for aneurysmal subarachnoid hemorrhage (aSAH) patients suffering cerebral vasospasm (CVS) cannot be overstated.
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Vasospasm, Cerebral, Transcutaneous Vagal Nerve Stimulation (tVNS), Endovascular Treatment
- Trial name
- NCT07131696
- Testing
- Transcutaneous Vagal Nerve Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Marshall Holland
Myocardial Infarction, Myocardial Reperfusion Injury
Efficacy of Endovascular Catheter Cooling Combined With Cold Saline for the Treatment of Acute Myocardial Infarction
The purpose of this study is to determine whether treatment of patients suffering from ST-elevation myocardial infarction (STEMI) with 1-2 liters of cold saline and central venous catheter cooling with Philips InnerCool RTx…
- Conditions
- Myocardial Infarction, Myocardial Reperfusion Injury, Anterior Wall Myocardial Infarction, Inferior Wall Myocardial Infarction
- Trial name
- CHILL-MI (NCT01379261)
- Testing
- Cooling
- Where
- 10 sites in Austria, Denmark and 2 more
- Volunteers
- 120 people
- Sponsor
- Region Skane
Endovascular Treatment
Prospective Registry Study of Endovascular Treatment for Acute Ischemic Stroke Patients
To investigate the real situation of assessment, diagnosis and treatment of acute ischemic stroke patients with endovascular therapy.
- Trial name
- NCT05988125
- Where
- 6 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Tingyu-Yi
Unruptured Intracranial Aneurysm, Intracranial Bifurcation Aneurysm
Early Complications After Flow Diverter Versus Stent-Assisted Coiling for Unruptured Wide-Neck Intracranial Bifurcation Aneurysms
This prospective real-world cohort study aims to compare early postoperative complications between flow diverter treatment and stent-assisted coiling in patients with unruptured wide-neck intracranial bifurcation aneurysms.
- Conditions
- Unruptured Intracranial Aneurysm, Intracranial Bifurcation Aneurysm, Wide-Neck Aneurysm
- Trial name
- FD-SAC BAS (NCT07754188)
- Testing
- Flow Diverter, Stent-Assisted Coiling
- Where
- 3 sites in China
- Volunteers
- 274 people
- Sponsor
- Nanfang Hospital, Southern Medical University