Clinical trials: Endovenous Laser Ablation
Varicose Veins
The BRILLIANT Study
This trial was designed as a prospective, multi-center, randomized clinical trial of the FDA-cleared Vari-Lase Bright Tip Fiber compared to commercially available standard bare-tip laser fiber (control) to demonstrate the safety…
- Trial name
- BRILLIANT (NCT00618514)
- Testing
- Bright Tip Laser Fiber, Bare Tip Laser Fiber
- Where
- 7 sites in United States
- Volunteers
- 93 people
- Sponsor
- Vascular Solutions LLC
Chronic Venous Insufficiency C2 or Higher
Prospective Multicentric Trial Between Radiofrequency Ablation With VNUS Closure Fast ® and Endovenous Ablation With 1470 nm Diode Laser and Tulip Fiber ® for Treatment of Primary Venous Insufficiency.
Endovenous ablation of the greater saphenous vein has nowadays the same outcome as open crossectomy and stripping. The two most performed techniques for endovenous ablation are the endovenous laser ablation and the radiofrequency…
- Trial name
- VNUS vs TULIP (NCT01722019)
- Testing
- Tulip fiber, VNUS closure fast
- Where
- 3 sites in Belgium
- Volunteers
- 280 people
- Sponsor
- University Hospital, Ghent
Varicose Veins of Lower Limb
MicrOwave and laSer ablaTion Study (MOST Study)
To validate the safety and efficacy of microwave versus laser ablation of the great saphenous vein in patients with varicose veins of lower extremities
- Trial name
- MOST (NCT04726124)
- Testing
- Microwave Ablation Therapeutic Apparatus
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Varicose Veins, Venous Reflux
Retrospective Review of Saphenous Vein Incompetence: Venaseal Versus Endovenous Thermal Ablation
This study is a retrospective, chart review of treatment of patients with symptomatic varicose veins. Treated limbs must have the Great Saphenous Vein and/or Small Saphenous Vein treated with either cyanoacrylate closure…
- Conditions
- Varicose Veins, Venous Reflux, Venous Insufficiency
- Trial name
- VALUE (NCT04006184)
- Testing
- Chart review
- Where
- United States
- Volunteers
- 547 people
- Sponsor
- Lake Washington Vascular
Varicose Veins
The Effect of Laser Power and Fiber Traction Speed on the Outcomes of Endovenous Laser Ablation
A multicenter clinical randomized controlled trial, comparing of three different regimens of endovenous laser ablation with equal linear endovenous energy density in patients with insufficiency of the great saphenous vein (GSV).
- Trial name
- SLEDGE (NCT03037827)
- Testing
- Endovenous laser ablation (EVLA), Laser
- Where
- 2 sites in Russia
- Volunteers
- 203 people
- Sponsor
- Clinic of Phlebology and Laser Surgery, Chelyabinsk, Russia
Venous Thromboembolism, Varicose Veins
Caprini Score in Venous Surgery: a Prospective Cohort Study
The aim of the study is to make a validation of Caprini score in patients undergoing varicose veins surgery, especially endovascular procedures (endovascular laser treatment - EVLT, radiofrequency ablation - RFA…
- Trial name
- CAPSIVS (NCT03041805)
- Testing
- EVLT, RFA, USFS
- Where
- Russia
- Volunteers
- 3,000 people
- Sponsor
- Pirogov Russian National Research Medical University
Varicose Veins, Endovenous Laser Ablation
Concomitant or Sequential Phlebectomy After Endovenous Laser Therapy for Varicose Veins
Varicose veins of the leg often have superficial tributaries, which are often symptomatic and a major reason for coming to the doctor.
- Conditions
- Varicose Veins, Endovenous Laser Ablation, Phlebectomies
- Trial name
- EVLTAP (NCT02017106)
- Testing
- Endovenous Laser ablation and concomitant phlebectomies, Endovenous Laser ablation and sequential phlebectomies
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Venous Thrombosis Deep (Limbs), Venous Insufficiency (Chronic)(Peripheral)
Apixaban vs Rivaroxaban vs No Anticoagulant to Prevent EHIT After Great Saphenous Vein Laser Ablation
Endothermal heat-induced thrombosis (EHIT) is a thrombotic complication specific to endovenous thermal ablation of the great saphenous vein (GSV), for which no prophylactic regimen is standardized.
- Conditions
- Venous Thrombosis Deep (Limbs), Venous Insufficiency (Chronic)(Peripheral), Varicose Veins Leg, Venous Thrombosis
- Trial name
- NCT07699796
- Testing
- Apixaban, Rivaroxaban
- Where
- United States
- Volunteers
- 564 people
- Sponsor
- Heart, Artery, and Vein Center of Fresno
Venous Insufficiency
Safety and Efficacy of Endovenous Laser Ablation for the Resolution of Incompetent Perforator Veins
This trial is designed as a prospective, non randomized, single center clinical trial to determine the safety and efficacy of laser ablation of incompetent perforator veins.
- Trial name
- RELIEVE (NCT00565604)
- Testing
- Short Catheter Delivery
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions LLC