Clinical trials: Energy and Cognition
Chronic Cerebral Ischemia
Safety and Efficacy of Sequential Therapy With Mexidol® in Patients With Chronic Cerebral Ischemia
The purpose of this study is to evaluate safety and efficacy of sequential treatment with Mexidol® in patients with chronic cerebral ischemia (CCI).
- Trial name
- MEMO (NCT06834490)
- Testing
- Mexidol
- Where
- 14 sites in Russia, Uzbekistan
- Volunteers
- 318 people
- Sponsor
- Pharmasoft
Schizophrenia
Effects of 12 Weeks Walking on Cognitive Function in Schizophrenia
This study is a 12-week randomized-controlled clinical trial. It will be planned to conduct in a total of 120 male and female subjects from the Department of Psychiatry at Kaohsiung Chang Gung Memorial Hospital.
- Trial name
- NCT04411979
- Testing
- treatment-as-usual plus aerobic walking
- Where
- Taiwan
- Volunteers
- 85 people
- Sponsor
- Chang Gung Memorial Hospital
Mild Cognitive Impairment, Metabolic Syndrome
Dietary Ketosis: Fatty Acids Activate AMPK Energy Circuits Modulating Global Methylation
The study explores whether selective memory complaints (SMC), mild cognitive impairment (MCI) and the comorbidity of Metabolic Syndrome symptomatic of peripheral and cerebral hypo-metabolism with corresponding epigenetic shifts…
- Trial name
- NCT03319173
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Bristlecone Health, Inc.
Obesity
Low Energy Ketogenic Diet in Obese Subjects - the Impact on Whole Organism
The study evaluates the timeline of changes of body composition, physical and psychological performance, and biochemical markers of metabolism and inflammation responses to low energy ketogenic diet for loosing weight in obese…
- Trial name
- KETO (NCT03338452)
- Testing
- Low energy ketogenic diet
- Where
- Slovenia
- Volunteers
- 38 people
- Sponsor
- University of Primorska
General Health and Wellness, Energy and Vitality
M4C Nutraceutical Intervention Human Health Effects Pilot
This 3 month pilot study will be an unblinded, convenience sampling, nutraceutical intervention trial. Twenty fasted subjects will undergo a baseline health assessment via a questionnaire, baseline clinical chemistries, blood…
- Conditions
- General Health and Wellness, Energy and Vitality, Cognitive Function and Mental Health, Weight Management
- Trial name
- M4C Pilot (NCT06476236)
- Testing
- M4C
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Concordia University Wisconsin
Endurance Cycling Performance
The Effect of Diet Composition on Performance, Expenditure, Blood Lipids, and Appetite Hormones in Highly Trained Cyclists
This study employs a crossover design to evaluate the effect of two different diets (high carbohydrate vs. ketogenic) and corresponding test meals on endurance exercise performance, energy expenditure including resting metabolic…
- Trial name
- DCAP (NCT04097171)
- Testing
- Diet
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Intrinsic Capacity, Frailty
Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults
The ICOPE Brazil study aims to understand aging trajectories in Brazil, especially healthy aging trends based on intrinsic capacity, a collective of mental and physical capacities one may have to maintain their functional ability…
- Conditions
- Intrinsic Capacity, Frailty, Aging, Healthy Aging
- Trial name
- ICOPE-BR (NCT06968702)
- Volunteers
- 3,838 people
- Sponsor
- University of Sao Paulo
Calorie Deficiency, Fasting
Effects of Calorie Restriction and Cold Stimuli on Health-related Indicators, Cognitive and Motor Functions
The goal of this clinical trial was to identify if duration of acute calorie restriction (CR)/fasting or combination CR with cold stimuli have any effects on mental and physical health-related markers, and to clarify if different…
- Conditions
- Calorie Deficiency, Fasting, Cold Exposure
- Trial name
- NCT05545943
- Testing
- 2-days of zero calorie restriction and whole-body cold-water immersion, 6-days of calorie restriction, 2-days of zero calorie restriction without whole-body cold-water immersion
- Where
- Lithuania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Aging, Healthy Aging
Cognitive Vitality Pilot Study
This study's purpose is to evaluate the effects of a dietary supplement on cognitive function and psychological well-being in community-dwelling older adults aged 55+.
- Conditions
- Aging, Healthy Aging, Cognition, Memory
- Trial name
- NCT07208279
- Testing
- Axolt Brain Supplement
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Huntington's Disease
Creatine Therapy for Huntington's Disease
This study, CREST-HD, will examine the safety and tolerability of 8 grams of creatine in subjects affected by Huntington's disease (HD).
- Trial name
- NCT00026988
- Testing
- Creatine
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Energy Metabolism
Effect of a Physical Exercise Session Performed During a 24-34 Hour Fasting Period on Energy Metabolism and Cognitive Function in Healthy Adults
This study explores the impact of high-intensity exercise during fasting on energy metabolism and cognitive function in healthy adults.
- Trial name
- IMS (NCT05919979)
- Testing
- 34-hour fasting in sedentary conditions, 34-hour fasting with high-intensity exercise
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Metabolic Processes
The Effects of Differing Cognitive Task Demands on Whole-body Energy Metabolism and Cerebral Blood-flow: Modulation by Multivitamins/Minerals and Coenzyme Q10
When completing difficult tasks, the brain requires faster delivery of energy sources (oxygen and glucose) via the blood. There is evidence to suggest that some nutritional supplements may increase blood circulation in the brain…
- Trial name
- NCT02381964
- Testing
- Supradyn® (1RDA+CoQ10), Supradyn® (3RDA)
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Cognition, Appetite
Acute Effects of Paraxanthine on Energy and Focus
This study aims to evaluate the effects of paraxanthine (200 mg and 300 mg) on energy, focus, appetite, and cognitive performance in healthy adults.
- Conditions
- Cognition, Appetite, Mental Energy, Dietary Supplement
- Trial name
- PXN (NCT06628596)
- Testing
- Paraxanthine 200mg and 300mg
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Iovate Health Sciences International Inc
Huntington Disease
Utilization of 31P-Nuclear Magnetic Resonance Spectroscopy to Monitor Brain Energy Deficit in Huntington Disease
The purpose of this project is to study brain energy profile evolution at different stages of the Huntington disease.
- Trial name
- PRO-MH2 (NCT01696708)
- Testing
- 31-Phosphorus RMN Spectroscopy
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Physical Performance, Exercise Performance
The Acute Effects of Liquid IV's Pre-Workout Supplement on Muscle Endurance & Strength, Energy, and Cognition
The goal of this study is to learn if a new pre-workout supplement can improve exercise performance in healthy adults. It will also look at how the supplement affects mood and energy levels.
- Conditions
- Physical Performance, Exercise Performance, Endurance Exercise, Perceived Exertion
- Trial name
- NCT07225608
- Testing
- proprietary pre-workout supplement
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Electromyography, Pressure Injury of Back
Active Versus Passive Sitting, Cognition and Energy
The study will compare cognitive capacity, muscle utilization patterns, soft tissue seated pressure and caloric output during four seated conditions: 1. passive sitting in a regular chair; 2.
- Trial name
- NCT07699848
- Testing
- Chaircise, Chaircise + Dynamic Leg Exercise, Chaircise + Static Leg Exercise
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Miami
Energy, Fatigue
A Clinical Trial to Assess the Effects of a Vitamin Shot on Energy Levels
This is a virtual, single-arm clinical trial that will last 30 days. Participants will drink 1 bottle of the Vitamin Energy® shot daily and complete questionnaires at baseline, Day 7, Day 14, and Day 30.
- Conditions
- Energy, Fatigue, Mood, Weight Loss
- Trial name
- NCT06019858
- Testing
- Vitamin Energy Shot
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vitamin Energy®
Healthy
Effects of Supradyn® Energy 3RDA on Fatigue/Stress, Substrate Metabolism During Exercise and Demanding Cognitive Tasks
Investigation of the acute and chronic effects of Supradyn® Energy 3RDA on subjective ratings of 'fatigue/stress', substrate metabolism and blood biomarkers of recovery, as a consequence of exercise and metabolically demanding…
- Trial name
- NCT03003442
- Testing
- Supradyn® Energy 3RDA
- Where
- United Kingdom
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Substrate Oxidation, Energy Expenditure
Exercise-Induced Rates of Fat Oxidation with and Without Ingestion of a Caffeine-Based Energy Drink
The purpose of this study is to evaluate acute changes in rates of fat oxidation during exercise with and without the ingestion of a caffeine-based energy drink.
- Conditions
- Substrate Oxidation, Energy Expenditure, Reaction Time, Cognition
- Trial name
- EDX (NCT06308731)
- Testing
- Caffeine-Based Energy Drink
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Skin Ageing, Healthy Ageing
Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age
This study evaluated the effects of a daily oral supplement regimen (Advanced ID Brain, Heart and Eye Omega Gel Capsules taken with Advanced ID Longevity and Collagen Complex Powder) on measures of skin condition, hair, sleep…
- Conditions
- Skin Ageing, Healthy Ageing, Effect of Oral Nutritional Supplementation on Skin, Hair, Sleep, Energy, Cognition and Sexual Wellbeing in Healthy Adults, Longevity
- Trial name
- IDF-AID-1 (NCT07827651)
- Testing
- Advanced ID
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- IDI Skincare Limited