Clinical trials: Enhanced Care
Psychotic Disorders, Schizophrenia
A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness
This is a prospective study using a concierge model of customized adherence enhancement and long-acting injectable antipsychotic (CAL-Concierge) in 30 individuals with schizophrenia or schizoaffective disorder at risk for…
- Conditions
- Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Medication Adherence
- Trial name
- CAL-C (NCT02085447)
- Testing
- CAE-L
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University Hospitals Cleveland Medical Center
HIV, Pregnancy
Kenya Enhanced Mentor Mother ProgrAm (EMMA)
Kenya recently adopted new treatment guidelines for pregnant women with HIV, which calls for all women to initiate triple-drug antiretroviral therapy (ART) at or soon after their first visit for antenatal care.
- Trial name
- NCT02848235
- Testing
- Standard of Care + EMMA
- Where
- 12 sites in Kenya
- Volunteers
- 363 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Coronary Disease, Cardiovascular Diseases
Evaluating a Web-Based Educational Program for Adults at Risk for Coronary Heart Disease (The Heart to Heart Feasibility Study)
Coronary heart disease (CHD) is the leading cause of death in the United States, but fewer than half of all individuals at risk for CHD take advantage of proven strategies to lower their chances of developing this disease.
- Trial name
- NCT00494052
- Testing
- Heart to Heart (Web-Based Decision Aid), Physician Education Session
- Where
- 2 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Knee Injuries, Shoulder Injuries
Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial
The investigators have previously reported on patient utilization of an eRehab patient education web portal that utilizes streaming, clinician prescribed video instruction to motivate and inform patients in self-care of their…
- Conditions
- Knee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus Tear
- Trial name
- NCT02025400
- Testing
- eRehab, Formal Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charlotte Sports Medicine Institute, PA
Brain Metastases, Brain Metastasis
Feasibility of a Cognitive Stepped Care Program for Adults With Brain Metastases
Background: Cognitive symptoms are common and often severe in patients with brain metastases, significantly impacting their quality of life and ability to manage cancer care.
- Trial name
- NCT07355348
- Testing
- Cognitive Stepped Care Program (CSCP)
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University Health Network, Toronto
Colorectal Cancer, Colorectal Neoplasms
Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery
The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications
- Trial name
- NCT07896174
- Testing
- Resistance Training Prehabilitation, Aerobic Training Prehabilitation, Standard Trimodal Care
- Where
- Hungary
- Volunteers
- 480 people
- Sponsor
- Semmelweis University
Diabetes Insipidus
Shared Health Appointments and Reciprocal Enhanced Support
The purpose of this study is to evaluate the effectiveness of a peer-to-peer program (P2P) in addition to Shared Medical Appointments (SMAs) compared to SMAs alone for the treatment of diabetes in five VA health systems, and to…
- Trial name
- SHARES (NCT02132676)
- Where
- 5 sites in United States
- Volunteers
- 1,536 people
- Sponsor
- VA Office of Research and Development
HIV Infections
A Waiting Room-Delivered Video to Enhance Clinical Outcomes Among Persons Living With HIV
The purpose of this project is to beta-test a brief waiting room video intervention that promotes early initiation of antiretroviral treatment among treatment-naïve HIV-positive patients, adherence to antiretroviral treatment and…
- Trial name
- TCOM (NCT03508310)
- Testing
- Taking Care of Me Video
- Volunteers
- 4,003 people
- Sponsor
- Centers for Disease Control and Prevention
PTSD, Physical Injury
IT Enhanced Peer Integrated Collaborative Care for US Trauma Care Systems
This study evaluates two readily implementable approaches to the delivery of transitional care for injured patients treated emergently in US trauma care systems.
- Trial name
- TSOS 7 Peer (NCT03569878)
- Testing
- Peer-Integrated Multidisciplinary Collaborative Care, Trauma surgery team notification
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- University of Washington
Colorectal Cancer
RCT on Elderly Patients Undergoing Colorectal Cancer Surgery With Enhanced Geriatric Care
This study evaluates the effects of enhanced geriatric input on elderly patients undergoing colorectal cancer surgery. Half of the participants will received additional pre, peri and post-operative care from the geriatric team…
- Trial name
- NCT02352688
- Testing
- Enhanced Colorectal Geriatric Care
- Where
- Hong Kong
- Volunteers
- 74 people
- Sponsor
- Chinese University of Hong Kong
Hyperkalaemia
Study of SZC and Enhanced Nutrition Advice Compared to SoC in Dialysis Patients With Hyperkalaemia
Prescribing Sodium zirconium cyclosilicate (SZC) with enhanced nutritional advice to participants with hyperkalaemia on haemodialysis will reduce serum K+ (S-K+ ) and enable the consumption of more fruit and vegetables and more…
- Trial name
- GRAZE (NCT04997161)
- Testing
- Sodium Zirconium Cyclosilicate (SZC), Enhanced dietary advice, Standard dietary advice including K+ restriction.
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- AstraZeneca
HIV/AIDS, Mental Health Issue
LinkPositively+ A Mobile Health App Delivered Intervention to Improve HIV Care Outcomes Among Black Women Affected by Mental Health and Violence
The investigative team will conduct a 2-arm randomized control trial to examine the preliminary effect of LinkPositively+ (LPP) an enhanced version of LinkPositively (LP) mobile app on improved HIV care outcomes including…
- Trial name
- LPP Plus (NCT06458660)
- Testing
- LPP+: Mindfulness Meditation Delivered, LP
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Guiding Right, Inc.
Behavioral Assessment of Children, Early Intervention
PaREnting ProgrAm to Enhance PREterm Infants' Health and Development (PREPARE Trial)
Preterm infants are at high risk of developmental delay or disabilities and they do benefit from early intervention programs. Many programs aiming at improving preterm infants' developmental outcome have been proposed with mixed…
- Trial name
- PREPARE (NCT04783220)
- Testing
- Comprehensive structured parent intervention
- Where
- Lebanon
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
ERAS, Enhanced Recovery
Impact Of The Nurse Enhanced Recovery After Surgery Coordinator On The Compliance In Colorectal Surgery (nursERAS-BCN)
Purpose. The aim of this study is to evaluate the impact of the implementation of the Nurse Enhanced Recovery After Surgery Coordinator (NEC), within the Enhanced Recovery After Surgery (ERAS) program, in relation to the…
- Conditions
- ERAS, Enhanced Recovery, Compliance, Treatment, Compliance, Patient
- Trial name
- nursERAS-BCN (NCT05231473)
- Testing
- Nurse Enhanced Recovery After Surgery participation
- Where
- Spain
- Volunteers
- 206 people
- Sponsor
- Hospital Universitari de Bellvitge
Hepatitis C, Opioid Use Disorder
Rural New England Health Study (Phase 2)
This study will integrate mobile hepatitis C virus (HCV) testing and treatment with expanded syringe access in order to improve uptake of HCV testing and treatment, and reduce syringe sharing behavior in rural northern New…
- Conditions
- Hepatitis C, Opioid Use Disorder, IV Drug Usage
- Trial name
- DISCERNNE (NCT05466331)
- Testing
- Mobile Tele-HCV Care, Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
COPD, Physical Activity
Effects of Adapted Snacktivity™ Intervention on Cognition and Self-Care in COPD Patients
This clinical trial aims to evaluate whether a culturally adapted Snacktivity™ program can improve cognitive function and self-care abilities in patients with Chronic Obstructive Pulmonary Disease (COPD) in Hong Kong.
- Conditions
- COPD, Physical Activity, Cognition, Self Care
- Trial name
- Snacktivity™ (NCT07702994)
- Testing
- Snacktivity™ Intervention, attention control
- Volunteers
- 210 people
- Sponsor
- The University of Hong Kong
Mental Health, Self Care
Impact of Psychosocial Support Web-Based Toolkit
At times of crisis, early childhood development (ECD) workers, and schools/centers play an important role in the lives of children in the early childhood stage (less than 8 years old) and their parents; they are intended to act…
- Conditions
- Mental Health, Self Care, Performance Enhancement
- Trial name
- NCT07289594
- Testing
- MHPSS Web-Based Toolkit
- Where
- Lebanon
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Arab Resource Collective
Psychosis
EPI-MINN: Targeting Cognition and Motivation
The purpose of this study is to perform a practice-based research project designed to assess whether cognition and motivated behavior in early psychosis can be addressed as key treatment goals within real-world settings by using…
- Trial name
- NCT05112432
- Testing
- Cognitive and Social Cognitive Training, Personalized Real-Time Intervention for Motivational Enhancement (PRIME) App, Early Psychosis Coordinated Specialty Care
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Minnesota
Hepatitis C
ETHOS ENGAGE: Enhancing Treatment of Hepatitis C in Opioid Substitution Settings
The overall goals of the ETHOS II Project are to enhance hepatitis C virus (HCV) care in drug treatment clinics and needle and syringe programs (NSPs) in New South Wales and Australia, and to develop a translational framework for…
- Trial name
- ETHOS II (NCT03685045)
- Testing
- Campaign days
- Where
- 32 sites in Australia
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Depression
Training and Supervision Program for Depression Management
According to the literature the management of depressive disorders at primary care level is not always consistent with guidelines.
- Trial name
- NCT02232854
- Testing
- Depression training/supervision program
- Where
- 4 sites in Chile
- Volunteers
- 256 people
- Sponsor
- University of Chile