Clinical trials: Enhanced Care
Smoking
Behaviorally Enhanced Counseling on Nicotine Dependence (BEACON) Trial.
The major purpose of this exploratory developmental study will be to develop a patient-centered and feasible protocol for communicating genetic data as it relates to drug efficacy for smoking cessation inpatients receiving…
- Trial name
- NCT00991081
- Testing
- Counseling, Self-help guide, Pharmacotherapy
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Stanford University
Substance-Related Disorders
Telephone Enhancement Procedure for Continuing Care - 1
The purpose of this study is to test a feasibility study of a telephone enhancement procedure (TELE) to improve participation in continuing care activities.
- Trial name
- NCT00067171
- Testing
- Behavior Therapy
- Where
- 4 sites in United States
- Volunteers
- 339 people
- Sponsor
- Duke University
Knee Injuries, Shoulder Injuries
Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial
The investigators have previously reported on patient utilization of an eRehab patient education web portal that utilizes streaming, clinician prescribed video instruction to motivate and inform patients in self-care of their…
- Conditions
- Knee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus Tear
- Trial name
- NCT02025400
- Testing
- eRehab, Formal Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charlotte Sports Medicine Institute, PA
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)
A Phase II Trial for MOR Antagonism With Axelopran to Enhance Immunotherapy in Head and Neck Cancer
This Phase 2, open-label, multicenter study will evaluate the safety and preliminary efficacy of axelopran in combination with pembrolizumab in patients with PD-L1 positive recurrent or metastatic head and neck squamous cell…
- Trial name
- MORALE-HN01 (NCT07662720)
- Testing
- axelopran, Pembolizumab
- Volunteers
- 18 people
- Sponsor
- Glycyx Therapeutics
HIV Infection, Drug Use
Linking Infectious and Narcology Care in Russia
The purpose of this study is to implement and assess a behavioral and structural intervention in Russia designed to support and motivate HIV-infected narcology heroin dependent patients (i.e., IDUs) to engage (i.e., initiate and…
- Trial name
- LINC (NCT01612455)
- Testing
- LINC Case Management
- Where
- 3 sites in Russia
- Volunteers
- 349 people
- Sponsor
- Boston Medical Center
Urinary Retention
The Effect of Tamsulosin on Postoperative Urinary Retention
This is a double-blinded randomized controlled trial of perioperative use of tamsulosin to prevent postoperative urinary retention in female pelvic reconstructive surgery undergoing same-day discharge with an enhanced recovery…
- Trial name
- NCT04682366
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Wake Forest University Health Sciences
Medication Adherence, Mobile Application
Mobile Application to Enhance Medication Management
Adverse drug events (ADEs) are a leading cause of death in North America, with over 2 million ADEs causing 100,000 deaths every year and millions in economic costs.
- Trial name
- SAM (NCT04676165)
- Testing
- Smart About Meds (SAM)
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- McGill University
Nurse Training
Integrating AI-Assisted Design Thinking Into Nursing Education
The goal of this randomized controlled trial is to test whether an AI-assisted design thinking workshop can improve empathetic communication in undergraduate nursing students at The Chinese University of Hong Kong.
- Trial name
- NCT07767292
- Testing
- AI-assisted design thinking workshop
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Opiate Dependence, HIV Seropositivity
Comparison of HIV Clinic-based Treatment With Buprenorphine Versus Referred Care in Heroin-dependent Participants
The purpose of this study is to compare the effectiveness of two approaches to treating HIV-infected patients who are addicted to opioid drugs (e.g., heroin) in an inner-city HIV clinic.
- Conditions
- Opiate Dependence, HIV Seropositivity, HIV Infections
- Trial name
- NCT00130819
- Testing
- Clinic-based substance abuse treatment with buprenorphine, Case management and referred substance abuse treatment
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Johns Hopkins University
Intimate Partner Violence
Domestic Violence Enhanced Perinatal Care Program in China
The proposed project addresses intimate partner violence (IPV) against pregnant women, which is a serious social and health issue.
- Trial name
- NCT05388565
- Testing
- Domestic Violence Enhanced Perinatal Care Program, Standard of Care
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Hepatitis C
ETHOS ENGAGE: Enhancing Treatment of Hepatitis C in Opioid Substitution Settings
The overall goals of the ETHOS II Project are to enhance hepatitis C virus (HCV) care in drug treatment clinics and needle and syringe programs (NSPs) in New South Wales and Australia, and to develop a translational framework for…
- Trial name
- ETHOS II (NCT03685045)
- Testing
- Campaign days
- Where
- 32 sites in Australia
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Geriatrics, Drug Therapy
Randomized Controlled Trial of Enhanced Pharmacy Care in Older Veteran Outpatients
Complications resulting from medications, or adverse drug events (ADEs), are prevalent and are a major source of excess morbidity and costs.
- Conditions
- Geriatrics, Drug Therapy, Poly Pharmacy
- Trial name
- NCT00122122
- Testing
- Enhanced Pharmacy Care
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- US Department of Veterans Affairs
Acute Kidney Injury
PRevention of Acute Kidney Injury Initiated With Electronic Surveillance Enhancement
Introduction: Acute kidney injury (AKI) increases mortality, hospital cost, and rate of progression toward end stage kidney disease 1-4. Early diagnosis and management of AKI is known to improve the above mentioned outcomes.
- Trial name
- PRAISE (NCT01621152)
- Testing
- Conventional management arm, AKI sniffer instigated AKI management
- Where
- United States
- Volunteers
- 2,266 people
- Sponsor
- Mayo Clinic
Community-acquired Pneumonia
Trial of Respiratory Infections in Children for Enhanced Diagnostics
The overall aim of the TREND study is to improve the differential diagnosis of bacterial and viral etiology in children below 5 years of age with clinical community acquired pneumonia.
- Trial name
- TREND (NCT03233516)
- Where
- Sweden
- Volunteers
- 376 people
- Sponsor
- Karolinska Institutet
Neonatal Patients Undergoing Major Non-cardiac Surgery, Congenital Anomaly
Neonatal Enhanced Recovery After Surgery (ERAS) Outcomes Study
The goal of this observational study is to improve the way newborn babies are cared for before, during, and after major surgery. Surgery can be very stressful on a baby's body.
- Trial name
- NEO (NCT07771478)
- Testing
- Pre-nERAS Guideline Implementation Intervention, Multifaceted Implementation of nERAS Guideline Intervention
- Where
- 3 sites in Canada, United Kingdom
- Volunteers
- 400 people
- Sponsor
- The Hospital for Sick Children
Critically Ill Patients, Mechanical Ventilation
Tight Glycemic Control by eMPC Algorithm in Medical ICU Patients.
This is an open mono-centre randomised controlled trial performed at the Medical University Graz including a treatment visit (V1).
- Conditions
- Critically Ill Patients, Mechanical Ventilation, Hyperglycemia
- Trial name
- NCT00460252
- Testing
- insulin titration applying a computer algorithm
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
Weight Loss, Obesity
A Trial to Test an Acceptance-based Therapy Program Among Adolescent Girls With Overweight/Obesity
The purpose of this study is to investigate the effects of an acceptance-based therapy weight loss intervention compared with enhanced care for adolescents.
- Conditions
- Weight Loss, Obesity, Overweight
- Trial name
- NCT04484831
- Testing
- ABT Weight Loss Intervention, Enhanced Care
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Florida
Maternal Care
Holistic Care Partner Program Feasibility and Acceptability
The study aims to build on the knowledge of the United States' ongoing maternal health crisis for Black birthing people. The study team will take a holistic focused approach to build on the experiences of Black women perinatal…
- Trial name
- NCT06520566
- Testing
- Holistic care partner perinatal nurse navigation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Abdominal Surgery, Postoperative Recovery
Effect of AI-Personalized Virtual Reality on Postoperative Recovery After Major Abdominal Surgery
Major abdominal surgery is frequently associated with postoperative pain, anxiety, delayed recovery, and prolonged hospitalization.
- Conditions
- Abdominal Surgery, Postoperative Recovery, Postoperative Pain, Length of Hospital Stay
- Trial name
- VR-RECOVER (NCT07493499)
- Testing
- Immersive Virtual Reality (VR), Standard Perioperative Care and Enhanced Recovery Protocol
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Alexandria University
Hypertension,Essential
Engaging Home-monitored Assessment to Navigate Clinical Decision-making
This study is testing a new app called ENHANCe, which is designed to help family doctors manage patients with high blood pressure using readings taken at home.
- Trial name
- ENHANCe (NCT07399912)
- Testing
- ENHANCe app, Teaching and training, Usual care
- Where
- Singapore
- Volunteers
- 116 people
- Sponsor
- SingHealth Polyclinics