Clinical trials: Enhanced Care
Solid Tumor, Adult
A Pilot Study of Genetic Testing Uptake Through Enhanced Oncology Nurse-Led Intervention
Genetic factors are a significant determinant of the likelihood of developing various types of cancers. Identification of germline risk can have important implications for both patients and their families.
- Trial name
- GENESIS (NCT06436157)
- Testing
- Enhanced education, Usual care education
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of California, Davis
Melanoma
Feasibility of an Enhanced Symptom Monitoring and Expedited Subspecialty Care Referral Intervention to Improve Side Effect Management for Patients With Melanoma Receiving an Immune Checkpoint Inhibitor
This clinical trial tests the feasibility of patient reported outcomes monitoring with early, rapid immunotherapy toxicity subspecialty care to improve side effect management for patients with melanoma receiving an immune…
- Trial name
- NCT07660666
- Testing
- Electronic Health Record Review, Internet-Based Intervention, Patient Navigation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Diabetes
Diabetes Interprofessional Team to Enhance Adherence to Medical Care
The overall goal of this randomized controlled trial is to test the efficacy of DM I-TEAM (Diabetes Interprofessional Team to Enhance Adherence to Medical Care) to reduce emergency department (ED) visits and hospitalizations over…
- Trial name
- DM I-TEAM (NCT03393338)
- Testing
- DM I-TEAM
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Thomas Jefferson University
Medication Therapy Management, Pharmacogenomics
Implementation Study of Enhanced Medication Therapy Management in Primary Care Practice
The purpose of this study is to identify challenges and successes associated with implementing an enhanced medication therapy management service in primary care practice.
- Trial name
- EMTM (NCT02748148)
- Testing
- Medication therapy management
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Tabula Rasa HealthCare
Tuberculosis
Using SMS Reminders, Phone Calls and Money Incentives to Enhance Linkage to Care of Presumptive TB Patients in Uganda
The major challenge in meeting the WHO's End TB Strategy- reducing tuberculosis (TB) deaths by 90% and incidence by 80% is the cascading patient loss-to-follow-up (LTFU) along the continuum of TB care.
- Trial name
- MILEAGE4TB (NCT05964842)
- Testing
- SMS, Phone call, Mobile money incentive
- Where
- 5 sites in Uganda
- Volunteers
- 2,355 people
- Sponsor
- Makerere University
Multimorbidity, Cognitive Impairments
Video-Enhanced Care Management for Medically Complex Veterans
The purpose of this study is to examine the feasibility and acceptability of a 12-week care management program for medically complex Veterans with cognitive impairment, delivered via telephone or videoconferencing.
- Trial name
- NCT02962687
- Testing
- Care management via videoconference, Care management via telephone calls
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
Osteoarthritis
Tranexamic Acid in Knee Joint Surgery
Total knee joint replacement surgery can lead to significant blood loss, which can affect recovery after surgery. Tranexamic acid (TXA) is a medication which stops the breakdown of blood clots and therefore prevents blood loss.
- Trial name
- TRACKS (NCT02278263)
- Testing
- Tranexamic Acid, Normal saline (0.9% NaCl)
- Where
- 5 sites in New Zealand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Andrew G Hill, MBChB, MD (Thesis), EdD, FACS, FRACS
Hearing Loss
New Algorithms to Signal Processing for Speech Enhancement in Adult Cochlear Implant Recipients.
The purpose of this clinical investigation is to develop pre-processing strategies to enhance speech and reduce noise for CI listeners.
- Trial name
- PRESENCE-MU (NCT06100393)
- Testing
- Investigational Pre-Processing Algorithm (Sub A), Cochlear Limited standard-of-care pre-processing algorithms, Investigational Pre-Processing Algorithm (Sub B)
- Where
- 2 sites in Australia
- Volunteers
- 150 people
- Sponsor
- Cochlear
Oral Health
Involving Parents to Improve Tooth Brushing for Autistic Children.
Parents of autistic children have reported a lack of understanding by oral health care staff around delivery of oral health preventive habits for their children.
- Trial name
- NCT06855693
- Testing
- Delivering better oral health: an evidence-based toolkit for prevention, Mini Mouth Care Matters guide for special Education Settings
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- Sussex Community NHS Foundation Trust
Medication Adherence, Self Management
Medication Adherence Enhancement in Heart Transplant Recipients
Medication-related non-adherence increases the risk of rejections and associated graft loss after solid organ transplantation. A randomized controlled intervention will use adherence enhancing strategies out of a larger sample of…
- Conditions
- Medication Adherence, Self Management, Rejection
- Trial name
- NCT00843960
- Testing
- behavioral adaptation and symptom management
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Hannover Medical School
Obstructive Sleep Apnea Syndrome
Trained Patient Involvement to Promote the Resumption of CPAP in Patients Who Have Discontinued Its Use
The primary objective of this randomized clinical trial is to evaluate the role of patient researchers in promoting the resumption of CPAP therapy in apneic patients who had previously stopped CPAP
- Trial name
- NCT04538274
- Testing
- peer-driven intervention
- Volunteers
- 208 people
- Sponsor
- AGIR à Dom
Gout
Using Gout Buddy to Enhance Gout Management
Background: Dietary management is crucial for gout, but patients often lack adequate dietary literacy. However, patients often lack adequate dietary literacy and struggle to navigate complex dietary recommendations.
- Trial name
- GOUTBuddy (NCT07004231)
- Testing
- GOUT Buddy, an AI chatbot
- Where
- Singapore
- Volunteers
- 110 people
- Sponsor
- SingHealth Polyclinics
Peptic Ulcer Perforation, Perforated Bowel
ERAS vs Conventional Approach in Peptic Perforation-RCT
This study compares 2 different ways of perioperative management in patients of peptic perforation. Experimental arm is the ERAS arm( Enhanced recovery after surgery) and the comparative arm is Conventional arm.
- Conditions
- Peptic Ulcer Perforation, Perforated Bowel, Post-Op Complication, Emergencies
- Trial name
- ERASE (NCT04194060)
- Testing
- Enhanced Recovery after Surgery group, Conventional
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Dementia
The Effect of Wearable Technology-Enhanced Intervention on Family Caregivers
This study aimed to evaluate the effect of a smartwatch-supported intervention on the self-efficacy and quality of life of informal caregivers providing care to individuals with dementia.
- Trial name
- dementia care (NCT06967688)
- Testing
- Smartwatch-Supported Caregiver Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Izmir University of Economics
Neurocritical Care, Traumatic Brain Injury
Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care
Enhanced recovery after surgery (ERAS) is a strategy of perioperative management aimed to accelerate the rehabilitation of patients through various optimized perioperative managements as well as ongoing adherence to a…
- Conditions
- Neurocritical Care, Traumatic Brain Injury, Cerebrovascular Disease, Moderate or Severe Coma
- Trial name
- NCT06241482
- Testing
- Enhanced recovery after surgery, Conventional therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai 6th People's Hospital
Polypharmacy
Evaluation of the Impact of a Collaboration Between Hospital and Community Pharmacists at Hospital Discharge
The aim of this study is to evaluate the impact of an enhanced collaboration between a hospital pharmacist and a community pharmacist during hospital discharge.
- Trial name
- NCT06902779
- Testing
- Support of the hospital pharmacist for the medication management at hospital discharge
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- Pharmacie des Hopitaux de l'Est Lemanique
Anemia, Hemolytic
Ferumoxytol Enhanced Hyperfine Low Field Strength MRI
The purpose of this pilot study is to evaluate the feasibility of using Ferumoxytol as a contrast agent on a low field strength, portable magnetic resonance imaging (MRI) system.
- Trial name
- NCT04721262
- Testing
- Hyperfine Portable MRI
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Prediabetes / Type 2 Diabetes, Diabetes Mellitus, Type 2
Pilot RCT of PIPE-AI for Prediabetes and Diabetes Self-Management
This pilot randomized controlled trial evaluates the feasibility, effectiveness, and acceptance of the Personalized Interactive Patient Empowerment Artificial Intelligence Platform (PIPE-AI) enhanced by DiabetesGPT among adults…
- Conditions
- Prediabetes / Type 2 Diabetes, Diabetes Mellitus, Type 2, Prediabetes
- Trial name
- PIPE-AI (NCT07787403)
- Testing
- PIPE-AI digital patient empowerment intervention, Waitlist usual care control
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Substance Use Disorders (SUDs)
Supportive Treatment With Enhanced Post-Incarceration Services
This study aims to improve health outcomes for people who use drugs after release from incarceration, a period of high risk for overdose and other adverse outcomes.
- Trial name
- STEPS (NCT07744841)
- Testing
- Individually Tailored Behavioral Activation, Formerly Incarcerated Transitions Program
- Volunteers
- 120 people
- Sponsor
- Catherine E. Paquette, PhD
Dementia, Prisoners
Computer-Based Learning to Enhance Dementia Care in Prison
The mission of corrections is to provide care, custody, and control for incarcerated individuals. United States prisons are required by law to provide adequate care for growing numbers of older people who are incarcerated-a group…
- Trial name
- NCT05497882
- Testing
- E-Learning Prototype for Dementia Care
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.