Clinical trials: Enhanced Care
Cardiovascular Diseases
Southwest Health Extension Partnership to Enhance Research Dissemination
Heart disease and strokes cause one in three deaths reported each year in the United States. Primary care practices need to implement new research findings that help decrease patients' risk for heart disease and stroke.
- Trial name
- NCT02515578
- Testing
- Enhanced practice transformation support, Standard practice transformation support
- Where
- United States
- Volunteers
- 5,508 people
- Sponsor
- University of Colorado, Denver
Alzheimer Disease, Dementia
Utilizing Senior Companions to Enhance Dementia Care
The inability of healthcare systems to effectively manage Alzheimer's disease and related dementias (ADRD) often results in families remaining unaware of important community-based, long-term services and supports (LTSS) that…
- Trial name
- NCT03667924
- Testing
- PorchLight Project
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Premature Birth, Pregnancy Preterm
Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study
This is a randomized comparative effectiveness study of two forms of enhanced prenatal care among 674 Medi-Cal eligible pregnant individuals in Fresno, California.
- Conditions
- Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety
- Trial name
- EMBRACE (NCT04154423)
- Testing
- Glow! Group Prenatal Care, Individual Prenatal Care with CPSP
- Where
- 2 sites in United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Disinfection
Impact of Enhanced Daily Disinfection on Environmental Contamination in Hospital Rooms
The purpose of this study is to determine if enhanced daily application of disinfectant with persistent 24-hour activity decreases the environmental bioburden compared to standard practice.
- Trial name
- NCT05739955
- Testing
- Sani24, Standard EPA-registered disinfectant, Routine Disinfection
- Where
- United States
- Volunteers
- 475 people
- Sponsor
- Duke University
Stroke
Getting on With the Rest of Your Life After a Stroke
The primary objective is to determine the extent to which participation in life's roles can be optimized through the provision of a community-based structured program providing the opportunity for physical activity, leisure, and…
- Trial name
- NCT01085240
- Testing
- Mission Possible
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- McGill University
Dementia
Compassion Pilot Intervention Study to Enhanced Integrated Care for People With Severe Memory Problems
The investigators developed the theory-driven 'Compassion Intervention', an integrated, interdisciplinary approach to address existing gaps in end-of-life care for people with advanced dementia.
- Trial name
- NCT02840318
- Testing
- Compassion Intervention
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- University College, London
Alcohol Abuse, Alcohol Dependence
Enhanced Motivational Interviewing With Alcohol Positive Trauma Patients
The primary goal of this study is to test the efficacy of a brief intervention that includes the patient and a significant other, relative to an intervention including the patient only, for reducing alcohol use and…
- Trial name
- NCT00280488
- Testing
- Motivational Interview, Assessment
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Brown University
Melanoma (Skin Cancer)
CARE-Melanoma Trial
Melanoma, a serious skin cancer, is increasingly prevalent in Canada. Surgical intervention is essential but poses significant physical and emotional challenges.
- Trial name
- CARE-Melanoma (NCT07320222)
- Testing
- Rehabilitation
- Volunteers
- 30 people
- Sponsor
- McMaster University
Alcohol Use Disorder
Brief Motivational Therapy Versus Usual Care for Alcohol Use Disorders in Primary Care.
Harmful alcohol use is a leading cause of global disability and death. However increased detection and brief intervention capacity of more severe alcohol use disorders (AUD) has not been accompanied by increased availability of…
- Trial name
- NCT04345302
- Testing
- Brief motivational treatment, Enhanced Usual Care
- Where
- 3 sites in Chile
- Volunteers
- 182 people
- Sponsor
- Nicolás Barticevic
Suicide Prevention
Practice Facilitation to Enhance Implementation of a Pediatric Suicide Prevention Pathway
Suicide in youth is rapidly growing to where it is the second leading cause of death across the United States. Use of available tools have shown the potential to boost primary care providers' (PCPs) detection of suicide risk and…
- Trial name
- NCT06619782
- Testing
- Practice Facilitation, Training in National Institute of Mental Health Youth Suicide Prevention Pathway
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Colorado, Denver
Total Hip Replacement, Total Knee Replacement
Dressing-related Experiences and Surgical Site Self-care in Hip and Knee Replacement: an Observational Cohort Study
The goal of this prospective observational cohort study is to investigate dressing-related experiences and surgical site self-care in patients who are undergoing a total hip or knee replacement.
- Trial name
- DRESS-X (NCT07471243)
- Testing
- Wound Dressing Material
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Bournemouth University
Health Workforce, Burnout
Relational Playbook Pilot Study
Background: The Veterans Health Administration (VA) is prioritizing employee well-being due to crisis levels of clinician burnout and turnover.
- Trial name
- NCT06456021
- Testing
- The Relational Playbook, Leadership Coaching
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder (PTSD), Depression
Stepped Enhancement of PTSD Services Using Primary Care (STEPS UP): A Randomized Effectiveness Trial
The overall objective of this study is to test the effectiveness of a systems-level approach to primary care recognition and management of PTSD and depression in the military health system.
- Trial name
- STEPS UP (NCT01492348)
- Testing
- STEPS UP, OUC
- Where
- 6 sites in United States
- Volunteers
- 666 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Chemotherapy-Induced Change
The Benefit of Enhanced Day Care of Traditional Chinese Medicine: A Retrospective Study of Medical Records
We collected medical records since June 2017 to November 2019., used pair-T test for questionnaire of CTCAE, BFT-I, WHOQOL to evaluate the benefit of enhanced day care of TCM for cancer patients.
- Trial name
- NCT04606121
- Testing
- enhanced day care of TCM include acupuncture, massage, tai ji quan, TCM herbal medicine
- Where
- Taiwan
- Volunteers
- 401 people
- Sponsor
- Taipei City Hospital
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Asthma
Asthma in Families Facing Out-of-pocket Requirements Due to COVID-19
In addition to its impact on health, the COVID-19 pandemic led to increased unemployment and loss of employer-sponsored insurance coverage.
- Trial name
- AFFORD COVID (NCT04613739)
- Testing
- insurance navigation
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Harvard Pilgrim Health Care
Colorectal Cancer, Enhanced Recovery After Surgery
CHASE : aCcelerated 23-Hour erAS Care for Colorectal Surgery
Rationale: Throughout the years, there has been a rapid change in the perioperative protocols and procedures surrounding colorectal surgery.
- Trial name
- CHASE (NCT04461275)
- Testing
- ERAS 2.0
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- Zuyderland Medisch Centrum
Sickle Cell Disease
Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease
The goal of this observational study is to help us understand more about the best ways to help individuals living with Sickle Cell Disease (SCD) get the best care.
- Trial name
- RECIPE (NCT06385886)
- Testing
- Linkage Coordinator
- Where
- 9 sites in United States
- Volunteers
- 500 people
- Sponsor
- RTI International
Insurance, Health
A Partnership Approach to Enhance Health Care Literacy
With the help of local focus groups, the investigators are designing and testing a website to help urban people have better access to health care through understanding their insurance options better.
- Trial name
- NCT02915003
- Testing
- E-health website
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Opioid Cessation
Motivational Interviewing and Guided Opioid Tapering Support to Promote Postoperative Opioid Cessation
The purpose of this study is to evaluate the relative efficacy of enhanced usual care versus motivational interviewing and guided opioid tapering support to promote opioid cessation after total hip or knee replacement surgery.
- Trial name
- NCT03659734
- Testing
- Motivational Interviewing and Guided Opioid Tapering Support, Enhanced Usual Care
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Stanford University