Clinical trials: Enteral Feeding Intolerance
Placental Insufficiency, NEC - Necrotizing Enterocolitis
Splanchnic Oxygenation Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler.
Antenatal absent or reversed end-diastolic flow (AREDF) velocity through the umbilical arteries places preterm infants at significant risk for developing gastrointestinal complications, such as feeding intolerance, necrotizing…
- Conditions
- Placental Insufficiency, NEC - Necrotizing Enterocolitis, Newborn, Premature, Feeding Disorder Neonatal
- Trial name
- AREDF-SO (NCT02971566)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Enteral Feeding Intolerance
The Effects of Bolus, Intermittent and Continuous Enteral Feeding on Blood Glucose and Feeding Intolerance in ICU Patients With Sepsis
Comparison of the effects of bolus, intermittent and continuous enteral feeding techniques on plasma glucose level and enteral feeding intolerance in adult intensive care unit patients with sepsis.
- Trial name
- NCT05812664
- Testing
- enteral feeding, blood glucose measurements, Evaluation of feeding intolerance with gastric residue
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Umraniye Education and Research Hospital
Feeding Intolerance, Necrotizing Enterocolitis
Enteral Granulocyte Colony Stimulating Factor and Erythropoietin Early in Life Increases Feeding Tolerance in Preterm Infants: A Randomized Controlled Trial
With preterm birth, the ingestion of amniotic fluid containing enterocyte trophic factors ceases abruptly. This likely predisposes them to villous atrophy feeding intolerance and necrotizing enterocolitis(NEC) once feedings are…
- Trial name
- NCT01441427
- Testing
- recombinant human G-CSF, and rhEPO, rh G-CSF, rh EPO
- Volunteers
- 93 people
- Sponsor
- Ain Shams University
Critical Illness, Nutritional and Metabolic Disease
Diarrhea and Stipsis in Critically Ill Patients (NUTRITI)
This study prospectively observed the complications intended as diarrhea or sti-sis that critically ill patients developed within 7 days after ICU admission.
- Conditions
- Critical Illness, Nutritional and Metabolic Disease, Nutritional Deficiency, ICU Acquired Weakness
- Trial name
- NUTRITI (NCT05473546)
- Testing
- ARTIFICIAL NUTRITION
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Gastrointestinal Dysfunction-induced Enteral Nutrition Intolerance
Efficacy of Fecal Microbiota Transplantation in ICU Patients With Gastrointestinal Dysfunction-induced Enteral Nutrition Intolerance
Considering that intestinal microbiota plays a crucial role in intestinal function, fecal microbiota transplantation (FMT) may provide a new therapeutic strategy for the treatment of intestinal nutrition intolerance in critically…
- Trial name
- NCT06603883
- Testing
- Fecal microbiota transplantation (FMT) by nasal jejunal tube
- Where
- 2 sites in China
- Volunteers
- 19 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Enteral Feeding Intolerance
Comparision of Two Different Feeding Method in Preterms
achievement of optimal postnatal growth by adequate enteral nutrition in critically ill preterm infants is a challenge of NICU. signs like abdominal distension, reflux, vomiting, nec is a factors of discontinuing fedding in…
- Trial name
- NCT05265143
- Testing
- bolus/intermittant feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Metabolism, Trauma
ImpACt of Very High Protein Content Enteral nUtrition Formulas on Critically Ill MUltipLe trAuma paTiEnts
This prospective observational randomized study aims to determine energy, protein intake and gastrointestinal tolerance while using enteral nutrition formulas with very high protein content and enteral nutrition formulas with…
- Conditions
- Metabolism, Trauma, Nutritional Deficiency, Protein Malnutrition
- Trial name
- ACCUMULATE (NCT05647135)
- Testing
- Medical food
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition
Gastroparesis
Evaluation of Single Doses of GSK962040 in Critically Ill Patients With Enteral Feed Intolerance
The aims of MOT112571 are to assess the pharmacodynamic effects, safety, tolerability, pharmacokinetics, and potential therapeutic benefit of single doses of GSK962040 in critically ill patients with delayed gastric emptying and…
- Trial name
- NCT01039805
- Testing
- GSK962040 (50 mg), GSK962040 (75 mg)
- Where
- Australia
- Volunteers
- 34 people
- Sponsor
- GlaxoSmithKline
Digestive System Neoplasms
Early Versus Delayed Parenteral Nutrition in Abdominal Surgical Patients
Patients will be randomized to early PN group or late PN group at day 3 after abdominal surgery. Patients will receive supplemental parenteral nutrition or not within 7 days after abdominal surgery.
- Trial name
- PNASIT (NCT03115957)
- Testing
- Parenteral Nutrition
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Jinling Hospital, China
Critical Illness, Enteral Feeding Intolerance
Evaluation of Enteral Nutrition in Critically Ill Children
The aim of this study was to evaluate the effect of calorie and enteral feeding timing on survival in critically ill children receiving inotropic, vasopressor and inodilatory supplements.
- Trial name
- NCT04013893
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Cukurova University
Feeding Intolerance, Abdominal Distension
Abdominal Binders to Minimize Enteral Nutrition Disruptions for Preterm Infants On Non-Invasive Respiratory Support
The goal of this study is to learn if a foam belly strap, called "NeoBellyBand," can help with belly bloating, pauses in feedings, feeding success, and earlier discharge home for preterm infants who are requiring pressurized…
- Trial name
- ABMENDPIONIR (NCT07219784)
- Testing
- An abdominal binder
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Albany Medical College
Intestinal Disease, Feeding Disorder Neonatal
Lactated Ringer's Solution in Neonates With Feeding Intolerance
The objective of this study is determining if enteral administration of Lactated Ringer's solution (LR) in preterm infants with feeding intolerance enables for faster advancement of milk feeding than fasting.
- Trial name
- LR (NCT01236833)
- Testing
- Lactated Ringer's Solution
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Critically-ill Patients
Itopride in Feeding Intolerance of Critically-ill Patients Receiving Enteral Nutrition
The current study will compare the effectiveness as well as the safety of Itopride against metoclopramide as the first line treatment for feeding intolerance in critically ill patients.
- Trial name
- NCT03698292
- Testing
- Itopride, Metoclopramide 10mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Enteral Feeding Intolerance, Critical Illness
Continuous Versus Intermittent Enteral Feeding and Gastric Residual Volume in Critically Ill Patients
This study will compare two commonly used methods of enteral feeding in critically ill adults: continuous feeding and intermittent feeding.
- Trial name
- NCT07876141
- Testing
- Continuous Enteral Feeding, Intermittent Enteral Feeding
- Where
- Vietnam
- Volunteers
- 76 people
- Sponsor
- Viet Duc University Hospital
Enteral Feeding Intolerance
A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance
This study is being conducted to evaluate the safety, tolerability and early efficacy of IV TD 8954 compared to metoclopramide in critically ill subjects, aged 18 to 85 years, who are admitted to the intensive care require…
- Trial name
- NCT01953081
- Testing
- TD-8954, Metoclopramide
- Where
- Australia
- Volunteers
- 13 people
- Sponsor
- Takeda
Enteral Feeding Intolerance, ICU
Transcutaneous Auricular Stimulation Targeting Enteral Feeding Intolerance
This study will test whether electrical stimulation applied to the outer ear can improve tolerance of tube feeding in critically ill adults in the intensive care unit (ICU).
- Trial name
- TASTE-FI (NCT07854236)
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Intra-Abdominal Hypertension
Application of Enteral Nutrition Program in Patients With Intra-abdominal Hypertension Oriented by Intra-abdominal Pressure
In this study, relevant contents of the enteral nutrition nursing programs for severe patients with abdominal pressure were systematically searched, and quality evaluation was carried out based on existing evidence.
- Trial name
- NCT05732545
- Testing
- enteral nutrition program for patients with abdominal hypertension guided by abdominal pressure
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Septic Shock
Splanchnic Perfusion Monitoring in Septic Shock Using Doppler Ultrasound
evaluation whether splanchnic Doppler ultrasound indices (SMA resistive index, portal vein pulsatility fraction, hepatic artery resistive index/flow parameters) can: 1.
- Trial name
- NCT07698834
- Volunteers
- 80 people
- Sponsor
- Assiut University
Critical Illness, Surgery
Diluted and Undiluted Enteral Nutrition
Adult patients after elective major abdominal surgeries who are planned to be admitted to the Intensive Care Unit (ICU) can be included in the trial. Each patient will be fed via the gastrointestinal tract.
- Conditions
- Critical Illness, Surgery, Enteral Feeding Intolerance, Gastro-Intestinal Disorder
- Trial name
- NCT06516835
- Testing
- Enteral fluid, Intravenous fluid
- Where
- 5 sites in Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Lublin
Aortic Aneurysm, Gastrointestinal Dysfunction
Gastrointestinal Dysfunction in Aortic Surgery Patients
The goal of this observational study is to determine the association of gastrointestinal dysfunction through the Gastrointestinal Dysfunction Scale (GIDS) tool and serum concentrations of citrulline and Intestinal fatty-acid…
- Conditions
- Aortic Aneurysm, Gastrointestinal Dysfunction, Aortic Diseases, Enteral Feeding Intolerance
- Trial name
- NCT06514170
- Testing
- No intervention
- Where
- Mexico
- Volunteers
- 114 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez