Clinical trials: Enteral Feeds
Critically Ill
Hypocaloric Enteral Nutrition in the Critically Ill Patient
The aim of this study is to compare two nutritional regimes in critically ill patients. Patients will be randomized to standard care (25 kcal per kg) or to hypocaloric nutrition (15 kcal per kg).
- Trial name
- hipoentnut (NCT02577211)
- Testing
- Hipocaloric enteral nutrition, Normocaloric enteral nutrition
- Where
- Colombia
- Volunteers
- 120 people
- Sponsor
- Lafrancol S.A.
Feeding Tube, Dysphagia
Safety and Usability Evaluation of the Fidmi Low-Profile Enteral Feeding Device
A First In Human Usability Open Label trial will be performed using the Fidmi Feeding device on 20 adult patients with a need for enteral feeding.
- Trial name
- Fidmi (NCT03007511)
- Testing
- Fidmi enhanced enteral feeding device
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Fidmi Medical
Enteral Feeding
Nutritional Tolerance and Safety of a Tube Feeding Formula in Children
To assess the efficacy, tolerance, and safety of a pediatric enteral formula in children.
- Trial name
- NCT05838495
- Testing
- formulated liquid diet
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Société des Produits Nestlé (SPN)
Sepsis
Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis
The rapidity and the quality of fluid resuscitation in patients with severe sepsis are important factors for the prevention of secondary multi-organ failure.
- Trial name
- CRYSTMAS (NCT00464204)
- Testing
- 6 % Hydroxyethylstarch 130/0.4 = "Voluven®", 0.9 % NaCl
- Where
- 24 sites in France, Germany
- Volunteers
- 196 people
- Sponsor
- Fresenius Kabi
Enteral Nutrition
Safety and Efficacy of an Amino Acid Blend on Muscle and Gut Functionality in ICU Patients
Assessment of the Safety and efficacy of an amino acid blend on muscle and gut functionality in Intensive Care Unit (ICU) patients.
- Trial name
- NCT02968836
- Testing
- Blend of amino acids, Maltodextrin only
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Société des Produits Nestlé (SPN)
Enteral Feeding Intolerance (EFI)
Efficacy, Safety, and Pharmacokinetics (PK) Study of Ulimorelin in Patients With Enteral Feeding Intolerance (EFI): The PROMOTE Trial
The purpose of this study is to evaluate the effect Ulimorelin in patients with enteral feeding intolerance.
- Trial name
- PROMOTE (NCT02784392)
- Testing
- Ulimorelin, Metoclopramide
- Where
- 5 sites in United States, Netherlands and 1 more
- Volunteers
- 120 people
- Sponsor
- Lyric Pharmaceuticals
Enteral Feeding
Tolerance of a Calorically Dense Enteral Nutrition Formula
This prospective observational study seeks to demonstrate the ability to meet nutritional needs of a calorically dense enteral formula in critically ill patients.
- Trial name
- NCT02806427
- Testing
- Enteral Formula
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Société des Produits Nestlé (SPN)
Malnutrition, Malabsorption
High Energy High Protein Peptide Feed Study
Oral nutritional supplements and enteral tube feeds are commonly used to meet the nutritional requirements of patients with disease-related malnutrition, or who require medical nutrition support for other reasons.
- Trial name
- NCT03140371
- Testing
- High energy high protein peptide feed study
- Where
- 10 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Nutricia UK Ltd
Jejunostomy; Complications, Enteral and Supplement Feeds Adverse Reaction
Clinical Pilot Study of the Percutaneous Ultrasound Jejunostomy Procedure
The purpose of this study is to evaluate the feasibility and performance of the Percutaneous Ultrasound Jejunostomy (PUJ) procedure that utilizes a novel device (PUMA-J System) in conjunction with widely available ultrasound…
- Conditions
- Jejunostomy; Complications, Enteral and Supplement Feeds Adverse Reaction, Safety Issues
- Trial name
- NCT06095804
- Testing
- Percutaneous Ultrasound Jejunostomy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CoapTech
Critical Illness
Observational Cohort Study on the Use of Parenteral Nutrition and Clinical Outcomes in Adult Critically Ill Patients
The aim of this study is to characterise the use of clinical nutrition support, especially of parenteral nutrition that is administered directly into a vein, in adult patients with critical illness.
- Trial name
- NCT04143503
- Where
- 76 sites in Austria, Belgium and 9 more
- Volunteers
- 1,208 people
- Sponsor
- Fresenius Kabi
Critical Illness, Enteral Nutrition
TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)
The purpose of this study is to assess the treatment effect of intravenous TAK-954 in improving the average daily protein adequacy received through enteral nutrition in critically-ill participants developing EFI.
- Conditions
- Critical Illness, Enteral Nutrition, Enteral Feeding Intolerance
- Trial name
- NCT03477903
- Testing
- TAK-954, Metoclopramide, Normal Saline
- Where
- 44 sites in United States, Australia and 2 more
- Volunteers
- 1 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Developmental Disabilities
Feeding Trial in Pediatric Patients
This is a single center, prospective, non-randomized, uncontrolled, observational study of the use of an enteral nutrition product in pediatric patients with developmental disabilities.
- Trial name
- NCT01469117
- Testing
- enteral formula
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Société des Produits Nestlé (SPN)
Eosinophilic Esophagitis (EoE)
Trial of Partial Enteral Nutrition With Dairy Free Diet in Eosinophilic Esophagitis
This study aims to introduce a new dietary therapy for Eosinophilic Esophagitis (EoE) patients by using partial enteral nutrition (PEN) to enhance remission rates and explore how this approach affects immune function, gut…
- Trial name
- NCT07234825
- Testing
- Partial enteral nutrition (PEN) with dairy elimination, Dairy elimination alone
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kate Farms Inc
Prematurity
Dietary Protein in the Very-low-birth-weight Infant
In this randomized study The investigators aim to compare the growth of very-low-birth-weight (VLBW) infants fed either a high protein or a standard protein preterm infant formula.
- Trial name
- NCT01208493
- Testing
- preterm infant formula with high protein levels, preterm standard infant formula
- Where
- 4 sites in United States, Belgium and 2 more
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Crohn's Disease(CD)
Partial-enteral Nutrition Protocol for Crohn's Disease
A novel dietary intervention combining a standardized IBD diet (IBD-AID) with supplementation from a pea protein plant-based oral nutrition supplement (ONS) (Kate Farms Peptide 1.5) to improve protein, calorie, and nutrient…
- Trial name
- NCT07113431
- Testing
- IBD-AID diet combined with Kate Farms Peptide 1.5, IBD-AID diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kate Farms Inc
Enteral Feeding
Enteral Formula Tolerance of Standard Tube Feedings
This prospective observational study seeks to assess ability to achieve enteral feeding goals with standard tube feeding formulas.
- Trial name
- NCT02312271
- Testing
- enteral formula
- Where
- 3 sites in United States, Canada
- Volunteers
- 102 people
- Sponsor
- Société des Produits Nestlé (SPN)
Critically Ill
Pilot Study on Gastro-intestinal (GI) Enteral Nutrition (EN) Tolerance in Intensive Care Unit Patients
Specifically designed enteral formulations may improve the gastrointestinal tolerance during early enteral nutrition in the critically ill patient.
- Trial name
- SPIRIT (NCT01581957)
- Testing
- Specific Enteral Nutrition, Standard Enteral Nutrition
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- Société des Produits Nestlé (SPN)
Enteral Nutrition, Feeding Tube Placement
Case Series to Evaluate the Identification of Anatomical Markers Using the KANGAROO™ Feeding Tube
This is a prospective, single-center, open label, within-subject clinical trial to evaluate the identification of anatomical markers in the gastrointestinal tract using the IRIS feeding tube.
- Trial name
- NCT02430571
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Medtronic - MITG
Critical Illness, Enteral Nutrition
Optimizing Enteral Nutrition Regimen for Critically Ill Patients
Clinical Trial The goal of this clinical trial is to learn whether different enteral feeding cycles (18-hour, 20-hour, or standard 24-hour continuous feeding) improve outcomes for critically ill ICU patients who need tube…
- Conditions
- Critical Illness, Enteral Nutrition, Ventilator Associated Pneumonia, Hyperglycemia
- Trial name
- NCT07270939
- Testing
- 20-Hour Cycled Enteral Nutrition with a 4-Hour Fasting Window, 18-Hour Cycled Enteral Nutrition with a 6-Hour Fasting Window
- Volunteers
- 150 people
- Sponsor
- Hamad Medical Corporation
Cystic Fibrosis
Absorption and Safety With Sustained Use of RELiZORB Evaluation (ASSURE) Study
Protocol 0000498: Multicenter, open label study to evaluate the effect of sustained RELiZORB (immobilized lipase) cartridge use during enteral feeding on fat absorption, as well as safety and tolerability of sustained RELiZORB…
- Trial name
- ASSURE (NCT02750501)
- Testing
- RELiZORB (immobilized lipase) cartridge, Impact Peptide 1.5
- Where
- 10 sites in United States
- Volunteers
- 49 people
- Sponsor
- Alcresta Therapeutics, Inc.