Clinical trials: Enteral Nutrition Therapy
Allogeneic Stem Cell Transplant, Graft Versus Host Disease
Nutrition and Outcomes of Hematopoietic Cell Transplantation (HCT)
Retrospective case-note review to determine if nutrition via the enteral compared to the parenteral route results in better outcomes after haematopoietic cell transplantation.
- Conditions
- Allogeneic Stem Cell Transplant, Graft Versus Host Disease, Hematologic Malignancy, Stem Cell Transplant Complications
- Trial name
- NCT03419078
- Volunteers
- 484 people
- Sponsor
- Imperial College Healthcare NHS Trust
Malnutrition
Early Enteral Nutritional Supplementation on Patients With Oral and Oropharyngeal Cancer Undergoing Radio(Chemo)Therapy After Surgical
The target population in the present study is Chinese patients with oral and oropharyngeal cancer who plan to receive radio(chemo)therapy after surgical resection in the outpatient department.
- Trial name
- NCT03545490
- Testing
- Early nutritional intervention
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Critically Ill
Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients
Critically ill patients are consistently underfed. Feeding protocols are standardized system tools used to guide nutrition practices, but to date have failed to improve delivery of nutrition.
- Trial name
- PEPuP (NCT01167595)
- Testing
- PEP uP Protocol
- Where
- 18 sites in United States, Canada
- Volunteers
- 1,059 people
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital
Low Birth Weight Infant, Enteral Nutrition
Oral Versus Intravenous Rehydration for Prevention of Dehydration in Premature Babies, During the First Days of Life.
This prospective randomised study comparing administration of a hypo-osmolar oral hydration solution with the classical hydration via IV (intravenous) infusion in premature infants of more than 32 weeks GA (gestational age) aims…
- Trial name
- SROPREMA (NCT00715000)
- Testing
- Oral rehydration therapy, classical hydration via intravenous infusion
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Feeding Patterns, Sleep
The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU
The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadian rhythms, and improves overall inflammation and cardiometabolic…
- Conditions
- Feeding Patterns, Sleep, Glucose Intolerance
- Trial name
- NCT04737200
- Testing
- Time-of-day of enteral nutrition provision (daytime first), Time-of-day of enteral nutrition provision (nighttime first)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Acute Lymphoblastic Leukemia, Malnutrition
Effect of Enteral Docosahexaenoic Acid Administration in Children With Acute Lymphoblastic Leukemia
The purpose of this study is to evaluate if enteral docosahexaenoic acid (DHA) administration during the first three months of treatment reduces the deterioration of nutritional status, treatment toxicity and early mortality in…
- Trial name
- DHA-ALL (NCT01051154)
- Testing
- Docosahexaenoic acid (DHA)
- Where
- Mexico
- Volunteers
- 72 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Crohn's Disease, Active
Partial Enteral Nutrition as Therapeutic Augmentation of Advanced Pharmacological Therapy in Patients With Active Crohn's Disease
This is a multicenter non-randomized prospective open label trial of partial enteral nutrition (PEN) among patients with active Crohn's disease (CD) starting standard of care advanced therapy.
- Trial name
- PANDORA (NCT07356232)
- Testing
- Partial enteral nutrition - orally consumed formula
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- James Lewis
Lymphoma, Myeloma
Evaluation of the Success of Prophylactic Enteral Nutrition in Therapeutic Intensification With Autograft of Autologous Hematopoietic Cells in Hematology
When the digestive tract is functional, learned societies recommend the use of a nutritional support by enteral feeding. Indeed, it has many advantages (maintenance of gut trophicity, reduction of the risk of infection by…
- Trial name
- GAGNE (NCT04703985)
- Testing
- Enteral Nutrition
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bordeaux
Patent Ductus Arteriosus
Feeding During Ibuprofen or Indomethacin Treatment of Preterm Infants
We hypothesize that feeding preterm infants while they receive indomethacin or ibuprofen therapy for treatment of a patent ductus arteriosus will decrease the incidence of feeding intolerance and shorten the time period that…
- Trial name
- NCT00728117
- Testing
- feeding, fasting
- Where
- 14 sites in United States
- Volunteers
- 177 people
- Sponsor
- University of California, San Francisco
Alcoholic Hepatitis
N-Acetylcysteine in Severe Acute Alcoholic Hepatitis
Acute alcoholic hepatitis (AAH) is the most severe form of alcoholic liver disease (ALD) and is associated with a high risk of dying in the short term.
- Trial name
- NCT00962442
- Testing
- N-Acetylcysteine
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- Erasme University Hospital
Environmental Enteric Dysfunction
PTM202 for the Treatment of Environmental Enteric Dysfunction (EED)
The purpose of this study is to assess the effectiveness of PTM202 in treating environmental enteric dysfunction.
- Trial name
- NCT03263871
- Testing
- PTM202, micro-nutrient sprinkles
- Where
- Bangladesh
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Critical Illness, Enteral Nutrition
Optimizing Enteral Nutrition Regimen for Critically Ill Patients
Clinical Trial The goal of this clinical trial is to learn whether different enteral feeding cycles (18-hour, 20-hour, or standard 24-hour continuous feeding) improve outcomes for critically ill ICU patients who need tube…
- Conditions
- Critical Illness, Enteral Nutrition, Ventilator Associated Pneumonia, Hyperglycemia
- Trial name
- NCT07270939
- Testing
- 20-Hour Cycled Enteral Nutrition with a 4-Hour Fasting Window, 18-Hour Cycled Enteral Nutrition with a 6-Hour Fasting Window
- Volunteers
- 150 people
- Sponsor
- Hamad Medical Corporation
Allogeneic Hematopoietic Stem Cell Transplant (Allo-HSCT)
Enteral Nutrition Versus Standard of Care in Allogeneic Hematopoietic Stem Cell Transplantation
This is a randomized controlled phase II trial which will enroll 112 patients with a diagnosis of a blood cancer or a serious blood disorder who plan to undergo an allogenic hematopoietic stem cell transplant using any…
- Trial name
- NCT07315165
- Testing
- Enteral Nutrition
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Nebraska
Crohn's Disease
Partial Enteral Nutrition With a Unique Diet vs. Exclusive Enteral Nutrition for the Treatment of Pediatric Crohn's Disease
The purpose of this study is to assess the efficacy and tolerability of a novel dietary intervention for early CD based on partial enteral nutrition, and to compare it to the gold standard but difficult to implement dietary…
- Trial name
- NCT01728870
- Testing
- Unique Diet+Partial Enteral Nutrition, Exclusive Enteral Nutrition (Modulen)
- Where
- 3 sites in Canada, Israel
- Volunteers
- 74 people
- Sponsor
- Prof. Arie Levine
Urinary Bladder Neoplasms, Cystectomy
Radical Cystectomy, Nutrition and Convalescence
The purpose of this study is to determine whether a goal directed nutritional intervention can reduce the convalescence period for patients undergoing radical cystectomy (RC).
- Conditions
- Urinary Bladder Neoplasms, Cystectomy, Bladder Cancer
- Trial name
- NCT02238886
- Testing
- Parenteral nutrition. SMOFKABIVEN infusion in central vene. Fresenius Kabi
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Protein Feeding in Post-traumatic Injury Patients
Early and Adequate Protein Feeding Post-Traumatic Injury
A randomized, parallel-group, pilot study comparing the effect of the early addition of intravenous protein to enteral feeding as tolerated versus enteral feedings as tolerated alone immediately post traumatic injury.
- Trial name
- EMS (NCT02837861)
- Testing
- Routine Nutritional Support plus supplemental IV amino acids, Routine Nutritional Support
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston Medical Center
Crohn Disease
The Crohn's Disease Exclusion Diet With Early Dairy Introduction vs Partial Enteral Nutrition for Crohn's Disease
This study aims to evaluate a novel diet for adult Crohn's disease patients (The Crohn's Disease Exclusion Diet - CDED). Some of the patients in this study will receive the CDED combined with partial enteral nutrition (PEN)…
- Trial name
- CD-EDEN (NCT05606419)
- Testing
- CDED+PEN, CDED+dairy
- Where
- Greece
- Volunteers
- 44 people
- Sponsor
- Evangelismos Hospital
Trauma, Critical Illness
Enteral Glutamine Supplementation for the Patient With Major Torso Trauma
Glutamine is considered a conditionally essential amino acid during critical illness. After severe trauma, glutamine supplementation into the gastrointestinal tract may help maintain bowel function.
- Conditions
- Trauma, Critical Illness, Shock
- Trial name
- NCT00178581
- Testing
- Glutamine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Critical Illness
Nutrient Uptake During Continuous Enteral Feeding
Continuous enteral nutrition is used to feed patients in intensive care who are unable to eat normally. The goal of this observational study is to learn about the uptake of nutrients from feeding formula.
- Trial name
- NCT05628844
- Testing
- Continuous enteral feeding
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Felix Liebau
Head and Neck Cancer
Optimal Tube Feeding Method in Head and Neck Cancer Patients
The purpose of this study is to assess the optimal tube feeding method (bolus, gravity or pump) by analyzing percent weight loss, tolerance of enteral feeds, and percent of estimated calorie and protein needs in 60 patients with…
- Trial name
- NCT01536782
- Testing
- Bolus, Gravity, Pump
- Where
- United States
- Sponsor
- Baylor Research Institute