Clinical trials: Environmental Conditions
Meningioma
Androcur® (Cyproterone Acetate) and Meningioma Development: a Genotype-environment Association Study
The primary objective of the study is to create a biobank of oral smears permitting to identify the genetic locus/loci associated with an increased risk to develop meningiomas after cyproterone acetate (CPA) (Androcur®)…
- Trial name
- ANDROMEDE-F (NCT04372095)
- Testing
- oral smears
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypoxemia, Physiological Stress
"Facemask Use During High-intensity Interval Exercise in Temperate and Hot Environments"
To investigate surgical mask use and high-intensity interval exercise across different environmental conditions.
- Trial name
- NCT05143801
- Testing
- High-intensity interval exercise with surgical face mask in a temperate environment, High-intensity interval exercise with surgical face mask in a hot environment, High-intensity interval exercise without using a surgical face mask in a hot environment
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Autism Spectrum Disorder (ASD)
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study
The goal of this observational study is to investigate the genetic and epigenetic mechanisms that may contribute to the development of Autism Spectrum Disorder (ASD) in individuals of different age groups.
- Trial name
- ASD-Omics-TR (NCT06662591)
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Research and Treatment Society of Genetic Disorders
Environmental-Pollution-Related Condition
Microplastica Pollution Awareness Level of Students
This study aims to raise awareness among individuals about plastic and microplastica pollution, reduce plastic consumption, reduce the amount of plastic waste that grows cumulatively every year, and contribute to the development…
- Trial name
- NCT06127862
- Testing
- Education group, No training was given
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Firat University
Obesity, Childhood, Child Development
El Sendero: Pathways to Health Study
This project will continue to follow two birth cohorts of mother-infant Latino dyads through a series of new assessments at age 6y, with an emphasis on examining the the role early nutritional exposures, exposures to…
- Trial name
- NCT05551650
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cough
Accuracy of Cough Detection in Healthy Adults
Cough is part of the defense mechanism to protect the lung from foreign particles and remove secretions from the airways. However, at times it becomes a bothersome, annoying symptom that interferes with the quality of life, sleep…
- Trial name
- NCT00907491
- Testing
- pulmonary sounds analyzer
- Where
- Israel
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- KarmelSonix Ltd.
Kidney Calculi, Ureteral Calculi
Impact of Humid-Heat on Gut-Tryptophan-Stone Pathway
Investigating the differences in gut microbiota composition and tryptophan metabolite levels between kidney stone patients and healthy individuals, with special focus on: 1.
- Trial name
- NCT07043374
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Obesity and Overweight
The Effects of Environmental Factors on the Macro-genome and Metabolism of Obese Patients.
The present study was designed to include obese patients diagnosed with obesity in the First Affiliated Hospital of Chongqing Medical University and a healthy control population.
- Trial name
- NCT06673433
- Testing
- obesity, health
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Dong Peng
Chronic Obstructive Pulmonary Disease, Healthy
Biosensor and Environmental Sensor Development Within the REMEDIA Project
The aim of this proof-of-concept study is to obtain data that will contribute to the development of sensor devices (biosensor and environmental sensor) for patients with lung diseases (e.g. COPD).
- Trial name
- NCT06035276
- Testing
- Exposure to clean air, Exposure to urban air
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Snoring
Snoring Intervention Via Elevoplasty in a Non-surgical Clinical Environment
Single Group Compared to Baseline, Non-Randomized, Multi-Center, Prospective Safety \& Efficacy Study
- Trial name
- SILENCE (NCT03083106)
- Testing
- Elevoplasty
- Where
- 6 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zelegent, Inc.
Glaucoma
Adult Providing Access to the Visual Environment (PAVE) - Glaucoma Pilot
We wish to evaluate a potential training program for patients with glaucoma, to become more efficient users of prescribed low vision devices for distance and near vision tasks.
- Trial name
- PAVE (NCT00338208)
- Testing
- Training in the Use of Low Vision Devices
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Down Syndrome, Child Obesity
HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome
The goal of this project is to evaluate an adapted health promotion program, HomeGrown, designed to improve the health of young children with Down syndrome by supporting families in making healthy home environmental changes.
- Trial name
- HomeGrown (NCT07296861)
- Testing
- The HomeGrown, Waitlist
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Caesarean Section;Stillbirth, Microbial Colonization
Lactobacillus Kefiri LKF01 (DSM32079) in Newborns Born by Caesarian Section
The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life.
- Trial name
- NCT03154866
- Testing
- Lactobacillus kefiri LKF01 DSM32079
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Spina Bifida, Anencephaly
Study of Genetic Risk Factors for Spina Bifida and Anencephaly
The purpose of this study is to describe the genetic contribution to the neural tube defects spina bifida (SB) and anencephaly (A), which includes identifying patients, defining the roles of certain genes, and studying…
- Trial name
- SBRR (NCT00031122)
- Testing
- No Intervention
- Where
- 2 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
HIV-1 Seropositive, Inflammation
Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
Background: Research has shown that certain proteins in cells may be linked to higher risks of developing inflammations, tumors, and other medical problems.
- Conditions
- HIV-1 Seropositive, Inflammation, Cancer, Cardiomyopathy
- Trial name
- NCT01143519
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Unrecognized Condition
Interaction of Genetic and Environmental Factors for Body Fat Mass Control
Although the effect of interaction between genetic and environmental factors on body fat mass (BFM) has been proposed, how lifestyle changes affect body weight with regard to the genetic composition needs to be verified.
- Trial name
- NCT04299698
- Testing
- lifestyle
- Where
- South Korea
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Emergency Contraception
A Study of Use of Ella®, an Emergency Contraceptive, Under Simulated OTC Conditions
This study is designed to assess whether consumers select and use ella® (ulipristal acetate 30mg), an emergency contraceptive, in a manner consistent with the OTC package directions in an OTC-like setting.
- Trial name
- LIBRella (NCT03208985)
- Testing
- Use Phase (Ulipristal Acetate, 30 mg)
- Where
- 34 sites in United States
- Volunteers
- 1,270 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Mild Cognitive Impairment, Mild Dementia
Gait Analysis by Induced Disorientation in a VR Environment
The aim of the study is to investigate whether the effect of disorientation on physical motion and gait among dementia patients, can be reliably measured in a laboratory environment, by means of a virtual reality (VR)…
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Disorientation, Young Adults
- Trial name
- NCT04134806
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Medical Center Rostock
Hypoxia, Altitude, Cold Exposure
Effects of Physical Training in Altered Environmental Conditions on Exercise Performance
The main objective of the study is to evaluate the physiological-biochemical effects of physical training under artificially altered climatic conditions (using a hypoxic thermoclimatic chamber) in particular to determine the…
- Conditions
- Hypoxia, Altitude, Cold Exposure, Heat Exposure
- Trial name
- NCT06159374
- Testing
- exercise and environmental conditions
- Where
- Poland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Inflammation
hsCRP Clinical Inflammation Marker for Human Bisphenol A Food Contamination
Dietary intervention studies thus far have failed to be replicable or causal.This is particularly relevant regarding plastic-derived chemicals (PDCs),This first-of-a-kind dietary intervention study explores a potential causal…
- Trial name
- NCT04600765
- Testing
- hsCRP serum measurement of inflammation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Center for Research on Environmental Chemicals in Humans