Clinical trials: Environmental Conditions
Respiratory Tract Infections, Transmission
Transmission Of Respiratory Tract microOrganisms In a School Environment
Through contact with peers in daycare and (primary)school young children play a large role in spreading respiratory pathogens. In this study the investigators will investigate this transmission, the subsequent colonization and…
- Conditions
- Respiratory Tract Infections, Transmission, Microbial Colonization, Viral Respiratory Tract Infection
- Trial name
- TORTOISE (NCT06248983)
- Where
- 2 sites in Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Overweight, Obesity
The Effect of PD01 on Cardiovascular Health and Microbial Environment
This randomized, placebo-controlled trial aims to determine the effects of daily administration of a carotenoid-producing Bacillus strain PD01 over a 6-week period on cardiovascular health biomarkers, microbiota composition and…
- Trial name
- NCT02622425
- Testing
- PD01
- Where
- Netherlands
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection
Optimizing Antibiotic Prescription in STI Clinics Using Rapid POCT
Sexually transmitted infections (STIs) caused by Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are increasing in France, with a significant proportion of asymptomatic infections.
- Conditions
- Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Sexually Transmitted Infections, Antimicrobial Resistance / Antibiotic Overuse
- Trial name
- OPTIMISE (NCT07884656)
- Testing
- cobas® Liat® CT/NG Point-of-Care Test
- Where
- 2 sites in France
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Hydration, Dehydration
The Effect of Proprietary Water on Physiological and Perceptual Responses
The purpose of this study is to determine if drinking proprietary water (PW) during a standardized daily plan as compared to distilled water (control) and carbohydrate-electrolyte (CE) drink can improve hydration status over…
- Trial name
- NCT05451446
- Testing
- proprietary water, Active comparator
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Atopic Dermatitis, Food Allergy in Children
Preventing Atopic Dermatitis and ALLergies in Children
The primary objective is of the PreventADALL study is to test if primary prevention of allergic diseases is possible by simple and low cost strategies, and secondary to asses the impact of xenobiotic exposure and microbiota in…
- Conditions
- Atopic Dermatitis, Food Allergy in Children, Asthma, Rhinitis, Allergic
- Trial name
- PreventADALL (NCT02449850)
- Testing
- Food intervention, Skin care
- Where
- Norway
- Volunteers
- 2,701 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Eating Behavior, Chronic Disease
JITAIs: Optimization of Effectiveness
The goal of this feasibility study is to get insight into the receptivity of a JITAI aimed at healthy dietary intake in inhabitants of a small city in the Netherlands.
- Trial name
- NCT05773625
- Testing
- Just-In-Time Adaptive Intervention
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Physical Activity, Adiposity
Effectiveness of a Physical Activity Intervention on Preventing Obesity During the Adiposity Rebound Period.
Coordinated project whose objectives are: a) to assess the effectiveness of a physical activity intervention (MOVI-KIDS) on preventing obesity and improving fitness during the adiposity rebound period; and b) to examine the…
- Conditions
- Physical Activity, Adiposity, Children, Obesity
- Trial name
- MOVI-KIDS (NCT01971840)
- Testing
- MOVI-KIDS
- Where
- Spain
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Meningioma
Androcur® (Cyproterone Acetate) and Meningioma Development: a Genotype-environment Association Study
The primary objective of the study is to create a biobank of oral smears permitting to identify the genetic locus/loci associated with an increased risk to develop meningiomas after cyproterone acetate (CPA) (Androcur®)…
- Trial name
- ANDROMEDE-F (NCT04372095)
- Testing
- oral smears
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06570993)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Heat Stress Disorders, Wounds and Injuries
Effects of Environmental Heat Exposure on Human Multiple Organ Function
This is a randomized controlled human exposure crossover study. Investigators aims to assess the acute effects of high temperature exposure and the underlying mechanisms.
- Conditions
- Heat Stress Disorders, Wounds and Injuries, Body Temperature Changes, Multiple Organ Dysfunction
- Trial name
- NCT06938932
- Testing
- High temperature exposure, Moderate temperature exposure
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Yinan Qu
Urinary Tract Infections, Malnutrition
Effect of Hygiene and Menstrual Hygiene Interventions on Learning and Psychosocial Wellbeing in Madagascar
A previous study in schools in rural Madagascar found that a bundle of hygiene-focused interventions substantially improved girls' learning outcomes.
- Conditions
- Urinary Tract Infections, Malnutrition, Inflammation, Stress
- Trial name
- KILONGA2 (NCT07702916)
- Testing
- Peer leadership/sensitization + sanitary pads, School infrastructure
- Where
- Madagascar
- Volunteers
- 3,080 people, healthy volunteers welcome
- Sponsor
- University of California Santa Cruz
Full Term Infants, Environmental Exposures
Epigenetic and Developmental Effects of In Utero Exposure to Environmental Toxicants
Metabolic diseases such as obesity and diabetes are modern day epidemics. Early life exposure to an adverse developmental environment, including environmental toxins, are linked to increased susceptibility to obesity, metabolic…
- Conditions
- Full Term Infants, Environmental Exposures, Adiposity
- Trial name
- NCT01815385
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
to Aid in Sperm Selection for ICSI
User Site Testing Study to Evaluate Usability of the Q300™ Device Under "Real-life Conditions" in a Reproductive Laboratory Environment Use
User Site Testing Study to evaluate usability of the Q300™ device under "real-life conditions" in a reproductive laboratory environment use.
- Trial name
- NCT06232720
- Testing
- Q300 QART Medical
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- QART Medical
Cerebral Palsy, Dyspraxia
Immersive Virtual Environments and Wearable Haptic Devices in Rehabilitation of Children With Neuromotor Impairments
The investigators proposed a controlled, single-blind, unicentric, crossover, randomized, clinical trial to test the effects of immersive virtual environments and wearable haptic devices in the rehabilitation of children with…
- Trial name
- SERIOUSGAME (NCT03353623)
- Testing
- Serious Game, Conventional Therapy
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Age-related Hearing Loss, Presbycusis
Genetic Study of Age Related Hearing Loss
Age-related hearing loss, or presbyacusis, is one of the most common chronically handicapped conditions for the elderly. Many factors including genetics, diet, diseases, drugs, socioeconomic factors and environmental variables…
- Trial name
- ARHL (NCT01732289)
- Testing
- genes
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Asthma (Diagnosis), Airway Inflammation
Can Astaxanthin Help Manage Asthma in POlluted Areas?
This study will test whether astaxanthin, a naturally occurring antioxidant supplement, can improve lung function, reduce airway inflammation, and improve asthma control in adults with mild-to-moderate asthma.
- Conditions
- Asthma (Diagnosis), Airway Inflammation, Airway Hyperresponsiveness
- Trial name
- NCT07507682
- Testing
- Astaxanthin Oral Capsule
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Middlesex University
Obesity, Childhood, Malnutrition
Physical Activity and the Home Environment in Preschool-aged Children in Urban Bangladesh
The overall goal of this study is to generate new knowledge regarding the nutritional and environmental determinants of physical activity in young children living in a densely populated urban community in Bangladesh.
- Conditions
- Obesity, Childhood, Malnutrition, Anemia
- Trial name
- NCT04628897
- Testing
- Exposures
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Diabetes Mellitus, Type 2, Overweight
Getting in Balance: A Workplace Diabetes Prevention Intervention Trial
This study evaluates two group-based Diabetes Prevention Program (DPP) lifestyle interventions delivered in the workplace to individuals at risk for pre-diabetes: 1) an in-person group-based lifestyle intervention; and 2) an…
- Conditions
- Diabetes Mellitus, Type 2, Overweight, Obesity
- Trial name
- GIBW (NCT02589873)
- Testing
- In-Person Diabetes Prevention Program, Online Diabetes Prevention Program
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Hyperthermia
Physiological and Thermoregulatory Responses of Body Cooling During Cycling in a Hot Environment
BHSAI is developing a computational system that provides early alerts of a rise in core body temperature to help reduce the risk of heat injury in the field and during training.
- Trial name
- PYTHON (NCT04715711)
- Testing
- Forearm coolng, Wet-towel cooling, mist-fan
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Asthma in Children, Allergy in Children
Project 500 CHILD Study
This proposal relates to the testing of several specific hypotheses in a subset of 500 participants in the Canadian Healthy Infant Longitudinal Development (CHILD) Study.
- Conditions
- Asthma in Children, Allergy in Children, Environmental Exposure, Genetic Predisposition
- Trial name
- NCT03225534
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- McMaster University