Clinical trials: Environmental Contamination
Second Hand Smoke, Exposure to Environmental Pollution
The Effect of a Zero Tolerance Program (SToP) on Child's Urine Cotinine Level According to Exposure Feedback
Although the ban on indoor smoking has greatly reduced secondhand smoke (SHS) exposure in public spaces, the home environment is still the primary source of exposure to SHS, particularly in children under the age of five.
- Conditions
- Second Hand Smoke, Exposure to Environmental Pollution, Child, Urine
- Trial name
- SToP (NCT05545748)
- Testing
- Zero (0) Tolerance Program (SToP), Exposure Feedback Group
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Pollution; Exposure
Scalability of a Home Health Navigator Program to Reduce Arsenic, Nitrate, and Lead in Private Well Water
Approximately 34 million Americans rely on private wells to supply their drinking water. Private wells are excluded from the Safe Drinking Water Act.
- Trial name
- NCT05395663
- Testing
- Community health worker
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Oregon State University
C. Difficile, Diarrhea
Impact of Oral Antibiotic Treatment on C. Difficile
The overall aim is to characterize and to compare the extent and quantity of C. difficile stool shedding, perianal colonization and environmental contamination in patients who received oral fidaxomicin, oral metronidazole, or…
- Conditions
- C. Difficile, Diarrhea, Enterocolitis
- Trial name
- C-Diff (NCT02057198)
- Testing
- Fidaxomicin, Metronidazole, Vancomycin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Duke University
Healthy 70 Street Market Vendors Working in Highly-polluted Areas of Turin
Biotics Intervention Oriented to Rescue From Environmental Pollution Inflammatory Responses
Improving air quality in urban areas represents a major public health challenge. In regions such as the Po Valley, airborne particulate matter (PM₁₀ and PM₂.₅) concentrations frequently exceed World Health Organization limits…
- Trial name
- BIOREPAIR (NCT07418489)
- Testing
- pro-postbiotic
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Environmental Contamination, Environment
The Effect of an Environmentally Based Education Program on Environmentally Friendly Behaviors
This study was conducted to determine the effects of an environmentally-based education program implemented for adolescents on their environmentally friendly behaviors and ecological footprint awareness.
- Trial name
- NCT07230678
- Testing
- Environmentally Based Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Cardiovascular Diseases
Environment and Cardiovascular Disease: The Corinthia Study
Environmental factors constitute an important but underappreciated risk factor towards the development and progression of cardiovascular disease (CVD).
- Trial name
- NCT03385122
- Where
- 2 sites in Greece
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Athens
Contaminated Medical or Biological Substances, Environmental-Pollution-Related Condition
Potential Risk for Bacterial Contamination in Ventilator Systems
Background: Few studies have investigated the difference of bacterial contamination between conventional reused ventilator systems and disposable closed ventilator-suction systems.
- Trial name
- NCT03359148
- Testing
- Disposable ventilator system, Conventional reused ventilator system
- Volunteers
- 27 people
- Sponsor
- Chang Gung University
Exposure to Environmental Pollution, Non-occupational
Interaction Effects of Temperature and Ozone
Purpose: The purpose of this protocol is to understand how individuals respond to the air pollutant ozone at elevated temperatures.
- Trial name
- TROPICOZ (NCT01981135)
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Urinary Tract Infection, Infection Due to ESBL Bacteria
Extended Spectrum Betalactamase Producing Bacteria; Epidemiology and Treatment in Non-hospitalized Patients
This project aims at investigating the duration of human fecal carriage of bacteria harboring plasmid-borne resistance genes expressing Extended Spectrum beta-lactamases (ESBL), risk factors for infections with such bacteria and…
- Conditions
- Urinary Tract Infection, Infection Due to ESBL Bacteria, Environmental Contamination of ESBL
- Trial name
- ESCAPE (NCT01838213)
- Volunteers
- 760 people
- Sponsor
- Vestre Viken Hospital Trust
Interstitial Lung Disease Due to Systemic Disease (Disorder), Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder)
Occupational and Environmental Exposures Analysis in Interstitial Lung Diseases.
The OCEAN-ILD study is designed to prospectively evaluate the prevalence and clinical relevance of environmental and occupational exposures in a large Italian cohort of patients affected by any ILD, using a standardised exposure…
- Conditions
- Interstitial Lung Disease Due to Systemic Disease (Disorder), Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder), Exposure Occupational, Occupational Exposure
- Trial name
- OCEAN-ILD (NCT07577115)
- Testing
- standard interview
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Clinico Humanitas
Nosocomial Infections
Potential Nosocomial Infection Prevention Via Modification of Anesthesia Intraoperative Aseptic Practice
We hypothesized that by improving hand hygiene compliance in the operative environment, we would reduce horizontal transmission of pathogenic bacteria to surgical patients.
- Trial name
- NCT00617006
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Exposure to Environmental Pollution
Characterization of Persistent Organic Pollutants Exposure During Preconception and Preimplantation Development.
In order to evaluate if gametes and preimplantation embryos are in vivo exposed to environmental chemicals, the detection of 6 molecules representative of 3 persistent organic pollutants families will be performed in the mucosa…
- Trial name
- TUBPOP (NCT04628091)
- Testing
- Sampling on surgery day
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Obesity and Overweight
A Clinical Study of the Effects of Environmental Pollution on Obesity
This study aims to assess the effects of environmental pollution (including environmental indicators such as PM2.5, PM5, PM10, SO2, NOX, O3, and greening index) on obese patients and to explore the possible mechanisms by which…
- Trial name
- NCT06670703
- Testing
- Obesity
- Where
- 3 sites in China
- Volunteers
- 800 people
- Sponsor
- Dong Peng
Fertility Disorders
Effects of Lifestyle Changes on Semen Quality in Healthy Young Men Living in Highly Polluted Areas (FAST)
We planned a randomized controlled trial (RCT) with the main aim to evaluate the effects of lifestyle changes on semen quality in healthy young men living in polluted areas in Italy.
- Trial name
- FAST (NCT04012385)
- Testing
- lifestyle counseling
- Where
- 4 sites in Italy
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale Salerno