Clinical trials: Environmental Exposure, open to volunteers
Environmental Exposure; Dietary Patterns; Nutritional Epidemiology; Human Biomonitoring
Assessing Toxic Metal Exposure From Vegetarian/Vegan, Omnivorous, and Low-carb Diets in Israel.
Different dietary intake may pose various health risks as as these have different potential exposure to heavy metals, which may originate from soils, irrigation systems, infrastructure, packaging, and other environmental…
- Trial name
- NCT07235332
- Testing
- Screening
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Environment, Sleep
Hospital Environmental Exposure
There is an increasing body of evidence that human health is affected by environmental factors such as air quality, noise and light. This applies to both indoor and outdoor environments.
- Conditions
- Environment, Sleep, Noise Exposure, Air Quality
- Trial name
- NCT06802367
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Leicester
D001305, Auditory Fatigue
Fatigue and Hearing Performance of Healthy Volunteers Acutely Exposed to Occupational Noise ( FATIGAUDIT)
Occupational noise exposure is regulated by law, and protective measures are applied if the noise level exceeds 90 dB(A). The inferior exposure levels can cause an auditory fatigue which is defined as temporary and reversible…
- Conditions
- D001305, Auditory Fatigue, Noise Exposure, Environmental Noise
- Trial name
- FATIGAUDIT (NCT07604077)
- Testing
- 2h30 of noise exposure at 85 dB(A), 2 noise exposures of 66 minutes, 10 noise exposure cycles
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Acute Aortic Syndrome
The EnvScore-Aorte Diagnostic Study Protocol for the Identification of Acute Aortic Syndrome
The goal of this retrospective observational study is to evaluate the diagnostic performance of the AORTAs score integrated with environmental exposure data (AORTAs-E) for the identification of Acute Aortic Syndrome (AAS) during…
- Trial name
- EnvScore Aorte (NCT07467486)
- Volunteers
- 580 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Lead Poisoning, Environmental Exposure
A Study to Assess the Efficacy of Public Health Campaigns in Reducing Lead Exposure
This clinical trial aims to evaluate the effectiveness of targeted public health campaigns in reducing lead exposure among adults living in urban communities with known environmental lead hazards.
- Trial name
- NCT07632937
- Testing
- Intensive Public Health Campaign, Standard Information Dissemination
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- International Health Strategies LLC
Anxiety, Suicidal Ideation
Climate Anxiety in a Young Population at Risk of Suicide
Climate change has become a major source of concern, particularly among younger generations who are facing the progressive degradation of ecosystems, loss of biodiversity, and alarming environmental information disseminated…
- Conditions
- Anxiety, Suicidal Ideation, Mental Health Issue, Environmental Exposure
- Trial name
- Anx-RS (NCT07305688)
- Testing
- Columbia Suicide Severity Rating Scale, Climate Change Anxiety Scale - French version, State-Trait Anxiety Inventory, French version
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Centre Hospitalier Esquirol
Prostate Cancer, Leukemia
Natural History Study of Early Life Exposures in Agriculture (ELEA)
Study Description: ELEA is an observational cohort study that will collect exposure information and biospecimens from the adult children of the Agricultural Health Study (AHS) cohort (https://aghealth.nih.gov/about; Protocol…
- Conditions
- Prostate Cancer, Leukemia, Breast Cancer, Melanoma
- Trial name
- NCT07328516
- Where
- United States
- Volunteers
- 64,277 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Exposure, Environmental, Genetic Predisposition
Precure Targeted Accrual and Rapid Growth in Enrollment Trial Study
The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and environmental contributors to disease, 3) identify ways to stop disease…
- Trial name
- TARGET (NCT07756320)
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Environmental Exposure, Asthma
Effects of Environmental Fungal Exposure on Bronchial Asthma, ABPA and Bronchiectasis
This study is a prospective, observational study of patients aged 18-80 years with clinical diagnosis of bronchial asthma, allergic bronchopulmonary aspergillosis (ABPA), bronchiectasis and healthy subjects.
- Conditions
- Environmental Exposure, Asthma, Bronchiectasis, ABPA
- Trial name
- NCT07313904
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Toxicant Exposure, Firefighter
Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)
This randomized, placebo-controlled crossover trial will test the feasibility and acceptability of using colesevelam in male firefighters with high per- and polyfluoroalkyl substances (PFAS) exposure.
- Conditions
- Toxicant Exposure, Firefighter, Occupational Exposure to Chemicals
- Trial name
- ENGINE (NCT07226440)
- Testing
- Colesevelam
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Cancer, Mental Health
Healthspan Connect Programme of Research
Healthspan Connect is a new research programme designed to understand what helps people stay healthy as they age. The programme will explore how lifestyle, environment, genetics, and social factors influence healthy ageing and…
- Conditions
- Cancer, Mental Health, Ageing Well, Resilience
- Trial name
- NCT07209774
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- King's College London
Asthma Childhood, Asthma
Advancing Diagnosis and Treatment of Pediatric Asthma
Asthma is one of the most common chronic diseases in children, and treatment success often depends on proper inhaler use and consistent medication adherence.
- Conditions
- Asthma Childhood, Asthma, Inhalation Spacers
- Trial name
- Care4Asthma (NCT07500246)
- Testing
- Whizz spacer system, AeroChamber Plus® Flow-Vu®
- Where
- Luxembourg
- Volunteers
- 208 people
- Sponsor
- Luxembourg Institute of Health
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Environmental Exposure, Pregnancy Related
Prenatal Education on Environmental Exposures During Pregnancy Study (PEEPS)
The purpose of this project is to reduce maternal environmental exposures to toxicants through a patient education program designed to help pregnant women learn about exposure through consumption of contaminated seafood and to be…
- Conditions
- Environmental Exposure, Pregnancy Related, Preterm Birth, Chronic Respiratory Disease
- Trial name
- PEEPS (NCT07758114)
- Testing
- Educational Intervention
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Heathly Subjects, Primary Health Care
Assessing the Effectiveness of Heat Adaptation Digital Messages From Primary Care Providers to Their Patients on the Change in Behaviour for Heatwave-related Preparedness
Extreme heat events pose a significant health threat in Canada, as demonstrated by the 2021 heat wave that claimed over 600 lives in Western Canada. Most heat-related deaths occur indoors and are preventable.
- Conditions
- Heathly Subjects, Primary Health Care, Climate Change, Public Health
- Trial name
- HeatSmart (NCT07024628)
- Testing
- Heat adaptation digital messaging, Non-heat-related digital messaging
- Where
- Canada
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Hopital Montfort
Stress (Psychology), Environment
Stress Through Audition: Uptake, Recovery, Oscillations During Nature Exposure
The protocol the investigators propose aims to address certain gaps by developing a multimodal paradigm, based on: Induction of acute stress via the Maastricht Acute Stress Test (MAST), a standardised protocol recognised for its…
- Trial name
- SAURON (NCT07857239)
- Testing
- Natural soundscape auditory exposure, Urban soundscape auditory exposure
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Allergic, Inflammatory
THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial Toxins
Background: Allergic and inflammatory conditions have been increasing over the years. Many factors may play a role in this. Every day, people are exposed to pollution and chemicals in our foods, clothing, and all of the cleaning…
- Trial name
- NCT07271381
- Testing
- Environmental Exposures, Control Exposures
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Myopia
Multicenter Evaluation of Near Vision and Outdoor Time in Kids Study
Currently, optical and pharmacological interventions have been developed to prevent the progression of childhood myopia. However, no myopia control strategy has been shown to have complete efficacy in controlling myopia…
- Trial name
- MENOK (NCT06119243)
- Testing
- Vivior
- Where
- 5 sites in United States, Australia
- Volunteers
- 230 people
- Sponsor
- The University of New South Wales
Breast Carcinoma
Environmental Exposure Assessment in High-Risk and Early-Onset Breast Cancer Care
This study evaluates patient and provider attitudes about environmental exposure risk assessments into clinical care for female patients at average or high risk for breast cancer and/or diagnosed with early onset breast cancer.
- Trial name
- NCT07690852
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Tooth Extraction Site Healing, Alveolar Ridge Preservation
Biomaterials Exposed to Oral Environment: Which One is the Appropriate Option?
After tooth extraction, bone loss can compromise future dental implant treatment. Dentists often use biomaterials to preserve bone, but in many cases these materials are left exposed to the oral environment, where saliva and…
- Trial name
- NCT07589751
- Testing
- Alveolar Ridge Reconstruction
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul