Clinical trials: Environmental Exposures
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Environmental Exposure
Assessing and Addressing Community Exposures to Environmental Contaminants
The purpose of this study is to build on our equitable, eight-year Tribal-academic partnership with the Ramapough Nation of northern NJ to advance tradition-centered farming practices and management strategies supporting…
- Trial name
- NCT06315140
- Testing
- Nutrition
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Behavioral Shift (Researcher Willingness to Report-back)
Impacts of a Report-back Training Program
Researchers participate in a hands-on training program on returning personal exposure results, and pre- and post-tests assess outcomes shifts in knowledge and perspectives on its value, and willingness to implement report-back in…
- Trial name
- NCT06046872
- Testing
- Report-back training
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Silent Spring Institute
Autonomous Subjects, Aged 65 and Afraid of Falling
Psychological and Postural Effects of Exposure to Both Types of Virtual Environments
The main aim of this study is to compare the fear of falling induced by each type of virtual scene (rocking and translation). Fear of falling will be assessed by a numerical fear of falling scale.
- Trial name
- PREUV (NCT04717895)
- Testing
- Rocking environment forward (B) followed by a translation environment, Translation environment followed by a rocking environment
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Gérond'if
Environmental Exposure, Physical Activity
Neurophysiological Mechanisms of Physical Activity Interventions in Unique Environments
This randomized intervention is designed to compare the influence of physical activity in natural and urban environments on cognitive and physical health.
- Trial name
- NCT03501953
- Testing
- Physical Activity
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northeastern University
Health Knowledge, Attitudes, Practice
Impacts of Clinician-Mediated Report-Back
The study trains clinicians to return personal exposure results to study participants in pregnancy cohorts, and measures outcomes for environmental health literacy for both clinicians and study participants.
- Trial name
- NCT06074159
- Testing
- In-clinic report-back
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Silent Spring Institute
Tobacco Smoke Pollution
Reduction of Environmental Tobacco Smoke (ETS) Exposure at Home: the BIBE Study
Main objective: to determine the effectiveness of a brief opportunist educational performance directed to the parents who smoke -- inside the context of programmed visits of paediatrics in primary care -- to reduce the exposure…
- Trial name
- BIBE (NCT00788996)
- Testing
- Brief intervention based in clinical practice guide
- Where
- Spain
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Sleep, Environmental Exposure
Sleep Improvement Via Environmental Smart Temperature Adjustments
Nearly 50% of older adults complain of poor habitual sleep, and in many cases the underlying reason remains undiagnosed or unknown.
- Conditions
- Sleep, Environmental Exposure, Environmental Sleep Disorder
- Trial name
- SIESTA (NCT06770400)
- Testing
- Temperature Optimized for Sleep, Participant's Preferred Temperature
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Environmental Exposure
Minority-focused Environmental Health Education and Tracking Pilot Study
The goal of this study is identify educational material related to EDC exposures that is culturally appropriate for the black community and test the usability of the material. The main questions this study aims to answer are: 1.
- Trial name
- MEET (NCT07461857)
- Testing
- Education curriculum
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Million Marker Wellness, Inc.
Environmental Exposure, Asthma
Effects of Environmental Fungal Exposure on Bronchial Asthma, ABPA and Bronchiectasis
This study is a prospective, observational study of patients aged 18-80 years with clinical diagnosis of bronchial asthma, allergic bronchopulmonary aspergillosis (ABPA), bronchiectasis and healthy subjects.
- Conditions
- Environmental Exposure, Asthma, Bronchiectasis, ABPA
- Trial name
- NCT07313904
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Air Pollution Exposure, Oxidative Stress
Savannah Environmental Nutrition Study (SENS): Nutrition Intervention to Reduce Air Pollution-Related Airway Inflammation and Oxidative Stress
This pilot clinical trial will evaluate the feasibility and potential health effects of a nutrition-based intervention among adults living in communities affected by air pollution near the Port of Savannah, Georgia.
- Conditions
- Air Pollution Exposure, Oxidative Stress, Airway Inflammation
- Trial name
- NCT07797413
- Testing
- Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Environmental Exposure
Behavioural Intervention to Decrease Exposure to Emerging Chemical Pollutants
The purpose of this study is to evaluate the effectiveness of a behavioural intervention designed to reduce exposure to environmental chemical pollutants among adults in Spain.
- Trial name
- INPOL (NCT07465315)
- Testing
- Guidelines from the public healthcare system, INPOL healthy lifestyle informative guidelines
- Where
- 5 sites in Spain
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Tobacco Prevention, Environmental Tobacco Smoke Exposure
The Impact of a Tobacco Control Intervention in African-American Families
The purpose of this randomized control trial is to evaluate the effects of a multi-component intervention aimed at: 1. preventing tobacco initiation in youth 2. promoting anti-tobacco socialization in the home 3.
- Conditions
- Tobacco Prevention, Environmental Tobacco Smoke Exposure, Tobacco Cessation
- Trial name
- NCT01164306
- Testing
- LifeSkills Training, Healthy Lifestyle Behavior Choices, NRT and Motivational Interviewing (MI)
- Where
- United States
- Volunteers
- 688 people, healthy volunteers welcome
- Sponsor
- Augusta University
Allergic Contact Dermatitis, Metal Allergy
Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases
The goal of this clinical trial is to collect environmental, bio-humoral, and clinical data derived from patients with allergic contact dermatitis (ACD) and systemic metal allergic syndromes related to the exposure to heavy…
- Conditions
- Allergic Contact Dermatitis, Metal Allergy, Food Allergy, Nickel Sensitivity
- Trial name
- MATRIOSKA (NCT06529913)
- Testing
- Collection of environmental, biological, and clinical data
- Where
- 2 sites in Italy
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Parkinson Disease, Secondary
Study on the Relationship Between Environmental and Occupational Exposure to Metals and Parkinson's Disease
The Department of Experimental Medicine - Section of Hygiene, Occupational Medicine, Forensic Medicine of the Second University of Naples, the Section of Neurology of the Second University of Naples and the Mediterranean…
- Trial name
- NCT02588924
- Testing
- Second University of Naples, Neuromed IRCCS
- Where
- 2 sites in Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Lead Poisoning, Environmental Exposure
A Study to Assess the Efficacy of Public Health Campaigns in Reducing Lead Exposure
This clinical trial aims to evaluate the effectiveness of targeted public health campaigns in reducing lead exposure among adults living in urban communities with known environmental lead hazards.
- Trial name
- NCT07632937
- Testing
- Intensive Public Health Campaign, Standard Information Dissemination
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- International Health Strategies LLC
Metabolic Disease, Neurological and Mental Health Conditions
Singapore PREconception Study of Long-Term Maternal and Child Outcomes
We aim to test the following primary hypothesis that nutrition, lifestyle, and maternal emotional health prior to pregnancy and/or during the first trimester alter the expression of metabolic or neurodevelopmental endophenotypes…
- Conditions
- Metabolic Disease, Neurological and Mental Health Conditions, Genetics Predisposition, Skin Condition
- Trial name
- S-PRESTO (NCT03531658)
- Where
- Singapore
- Volunteers
- 1,054 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Healthy Volunteer
Following of Atmospheric Pollution Exposure During Pregnancy and Effects on Health
The SEPAGES couple-child cohort is coordinated by an Inserm (French National Institute of Health and Medical Research) team of environmental epidemiology.
- Trial name
- SEPAGES-1337 (NCT02852499)
- Testing
- Urine sampling, Carry a GPS and BET, Carry pollution sensor
- Where
- France
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Exposure to Environmental Pollution, Non-occupational
Epigenetic Effect Modifications With Ozone Exposure on Healthy Volunteers
The purpose of this protocol is to assess whether epigenetic factors in healthy individuals make a person more or less responsive to lung inflammation following ozone exposures.
- Trial name
- Geminoz (NCT02469428)
- Testing
- Clean air, Ozone
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Heat Stress, Heat Exposure
Validity of Humidity Ramp Protocols for Identifying Limits of Survivability in Heat-exposed Persons
The global populace is at growing risk of heat-related illness due to climate change and accompanying increases in the intensity and regularity of extremely hot temperatures.
- Conditions
- Heat Stress, Heat Exposure, Temperature Change, Body, Temperature; Extreme, Exposure
- Trial name
- NCT05963529
- Testing
- Humidity-ramp protocol, Above-inflection fixed-condition exposure, Below-inflection fixed-condition exposure
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa