Clinical trials: Environmental Toxins
Autism
The Effects of a Clean Room Sleeping Environment on Elemental and Chemical Concentrations in Children With Autism
A child and their parent were asked to participate in a research project that sought to study whether sleeping in a very clean environment for 14 days improved the elimination of chemicals and metals from the child's body.
- Trial name
- NCT02195401
- Testing
- Cleanroom
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Children's Institute
Inflammation
hsCRP Clinical Inflammation Marker for Human Bisphenol A Food Contamination
Dietary intervention studies thus far have failed to be replicable or causal.This is particularly relevant regarding plastic-derived chemicals (PDCs),This first-of-a-kind dietary intervention study explores a potential causal…
- Trial name
- NCT04600765
- Testing
- hsCRP serum measurement of inflammation
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Center for Research on Environmental Chemicals in Humans
Allergic, Inflammatory
THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial Toxins
Background: Allergic and inflammatory conditions have been increasing over the years. Many factors may play a role in this. Every day, people are exposed to pollution and chemicals in our foods, clothing, and all of the cleaning…
- Trial name
- NCT07271381
- Testing
- Environmental Exposures, Control Exposures
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Varicocele, Male Infertility
Role of the Toxic Metal Cadmium in the Mechanism Producing Infertility With a Varicocele
Varicose veins in the scrotum (varicocele) are responsible for >20% of male infertility in the US. Varicocele are associated with decreased sperm number and markedly reduced sperm fertilizing ability.
- Conditions
- Varicocele, Male Infertility, Hypospermatogenesis, Non-Obstructive Azoospermia
- Trial name
- NCT00044369
- Testing
- Varicocele repair
- Where
- 2 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Crohns Disease, Pregnancy
Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation
The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of developing inflammatory bowel disease (IBD) as well as…
- Conditions
- Crohns Disease, Pregnancy, Inflammatory Bowel Disease
- Trial name
- PLANET (NCT06001450)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Type 1 Diabetes Mellitus
TEDDY - The Environmental Determinants of Diabetes in the Young
The long-term goal of the TEDDY study is the identification of infectious agents, dietary factors, or other environmental agents, including psychosocial factors which trigger T1DM in genetically susceptible individuals or which…
- Trial name
- NCT00279318
- Where
- 7 sites in United States, Finland and 2 more
- Volunteers
- 8,667 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
C535854, D004786
Investigating the Effects of Probiotic Yogurt on Reducing the Levels of Environmental Toxins Among School Children in Mwanza, Tanzania
The primary objective of this pilot study is to determine if consumption of a probiotic yogurt causes reduced levels of environmental toxins in a group of school-aged Tanzanian children.
- Trial name
- PDTX (NCT01904513)
- Testing
- Pasteurized Whole Milk, Lactobacillus rhamnosus GR-1
- Where
- Tanzania
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Malnutrition Pregnancy, Malnutrition in Children
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories
Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it.
- Conditions
- Malnutrition Pregnancy, Malnutrition in Children, Malnutrition (Calorie), Environmental Enteric Dysfunction
- Trial name
- UZBCS-2 (NCT07195006)
- Testing
- Malnutrition in pregnancy as exposure, Poor WASH living conditions as exposure
- Where
- Zimbabwe
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Healthy Adult Participants, Toxic Chemicals
Turkish Validity and Reliability Study of PRevention of Toxic Chemicals in the Environment for Children Tool
The aim of this study is to conduct a Turkish validity and reliability study of the "Prevention of Toxic Chemicals in the Environment for Children Tool," developed to examine the knowledge and attitudes of parents and prospective…
- Conditions
- Healthy Adult Participants, Toxic Chemicals, Environmental Toxins
- Trial name
- NCT07483606
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people
- Sponsor
- Istanbul University - Cerrahpasa
Environmental Toxins, General Health
Prospective Human Study Evaluating Changes in Markers of Detoxification, Overall Physical and Mental Health, and Fatigue Following Supplementation With CellCore Protocols
The primary purpose of this study is to evaluate the effects of CellCore protocols on environmental toxicant biomarkers among adult patients with high baseline toxicant levels.
- Trial name
- NCT07753798
- Testing
- CellCore Foundational Protocol, CellCore - BioToxin Binder & Drainage Activator
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- OvationLab
Vulvovaginal Candidiasis, Bacterial Vaginosis
Study of the Microbiota, Metabolome, and Environmental Toxins in Relation to Reproductive Health in Rwandan Women
The overall objective of this clinical pilot study is to determine at a random sampling time, the vaginal microbiome and metabolome of pregnant women, and to see if infection (bacterial vaginosis, vulvovaginal candidiasis…
- Trial name
- RVMM (NCT02150655)
- Testing
- Lactobacillus GR-1 and Lactobacillus RC-14 oral capsules
- Where
- Rwanda
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Gastrointestinal Diseases
Correlation of Toxins With Gastrointestinal (GI) and Overall Health
The goal of this observational study is to evaluate the levels of urinary environmental toxins, heavy metals, PFAS and mycotoxins with gastrointestinal (GI) and overall health.
- Trial name
- NCT06278311
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vibrant America Clinical Lab
Anxiety, Pain
Relaxing Environment to Lower Anxiety During Onabotulinum Toxin Chemodenervation of the Bladder
Chemodenervation of the bladder with onabotulinum toxin A is an effective treatment option for patients with refractory urgency urinary incontinence (UUI).
- Conditions
- Anxiety, Pain, Burnout, Professional
- Trial name
- RELAX (NCT06319898)
- Testing
- Lavender aromatherapy sticker
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Wake Forest University Health Sciences
Environmental Exposure to Harmful Algae and Toxins, Female Subfertility
Analysis of Toxins in Follicle Fluid
Environmental pollutants might be jointly responsible for increase of infertility among women. Especially endocrin active substances seem to be of particular importance.
- Trial name
- NCT01385605
- Where
- Germany
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund