Clinical trials: Eosinophilic Rhinitis
Eosinophilic Asthma, Chronic Sinusitis
Eosinophils Endotypes in Chronic Airway Inflammatory Diseases
Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) are frequently described as unified airway inflammatory diseases. Both heavily impacts quality of life with substantial productivity loss.
- Conditions
- Eosinophilic Asthma, Chronic Sinusitis, Eosinophilic Rhinitis
- Trial name
- PLEIAD (NCT04187976)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Lille
Food Allergy, Asthma
Assessing Risk of Food Insecurity Within Households of Children With Food Allergy
Our central hypothesis is that dietary limitations introduced by food allergy will contribute to increased food insecurity in households with food allergic children when compared to food insecure households without food allergic…
- Conditions
- Food Allergy, Asthma, Allergic Rhinitis, Atopic Dermatitis
- Trial name
- NCT01897506
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Type 2 Inflammatory Disorders
Compassionate Use or Expanded Access of Dupilumab
Provide Compassionate Use or Expanded Access of Dupilumab
- Trial name
- NCT04776694
- Testing
- Dupilumab
- Sponsor
- Regeneron Pharmaceuticals
Eosinophilic Esophagitis
The Role of HRM and Specific Biomarkers of Inflammation in the Diagnosis of Patients With Dysphagia and Suspected EoE
The aim of the project is to assess the correlation between the results of high-resolution oesophageal manometry and specific biomarkers of inflammation (eotaxin 3, major basic protein, IL-5, IL-13, TGF-beta1) with symptoms of…
- Trial name
- NCT04803162
- Testing
- High-resolution manometry, Serum biomarkers, Gastrointestinal Quality of Life index
- Where
- Poland
- Volunteers
- 58 people
- Sponsor
- Wroclaw Medical University
Allergy, Asthma
Evaluation and Long-Term Follow-Up of Patients With Allergic and Inflammatory Disorders
This study will evaluate and follow patients with various allergic, hypersensitivity and inflammatory disorders. The protocol is not designed to test new treatments; patients will be managed with standard of care therapies.
- Conditions
- Allergy, Asthma, Allergic Rhinitis, Mastocytosis
- Trial name
- NCT00557895
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Eosinophilic Esophagitis
Allergy Immunotherapy in the Management of Eosinophilic Esophagitis
Eosinophilic esophagitis (EoE) is a disease that has increased in incidence over the past decade that affects males predominantly, and in adults, is characterized by heartburn, dysphagia, strictures and food impactions.
- Trial name
- AIMEE (NCT01685034)
- Testing
- Allergy immunotherapy ("allergy shots")
- Sponsor
- United States Naval Medical Center, San Diego
Eosinophilic Esophagitis, Respiratory Allergy
Survey About the Relationship Beetween Allergic Rhinitis and Seasonal EOE Exacerbations
Eosinophilic esophagitis (EoE) is a chronic inflammatory esophagus disease that is presented in patients with a history of recurrent dysphagia.
- Trial name
- NCT05755477
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Nucera Eleonora
Chronic Rhinosinusitis (Diagnosis), Allergic Rhinosinusitis
Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis
Chronic rhinosinusitis (CRS) affects up to 12.5% of the US population and has a significant disease burden. The recommended medical management of CRS includes large-volume, low-pressure saline lavage, systemic antibiotics, and…
- Conditions
- Chronic Rhinosinusitis (Diagnosis), Allergic Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis
- Trial name
- NCT03705793
- Testing
- Mometasone Furoate Nasal Irrigation, Mometasone Nasal Spray
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis
The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis
The goal of this research project is to explore the impact of the addition of budesonide to high-volume, low-pressure nasal sinus saline irrigation (aka "Neti-Pot"-type systems) for patients with chronic rhinosinusitis with or…
- Conditions
- Rhinosinusitis, Chronic Eosinophilic Rhinosinusitis, Allergic Rhinosinusitis
- Trial name
- NCT02696850
- Testing
- Budesonide, Saline alone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Washington University School of Medicine