Clinical trials: Epicardial Adipose Tissue
Diabetes, Coronary Artery Disease
Epicardial Fat and Clinical Outcomes After Coronary Artery Bypass Grafting in Diabetics vs. Non Diabetics
Cardiovascular disease (CVD) is a group of diseases including both the heart and blood vessels, thereby including coronary heart disease (CHD). To date, diabetics have a higher incidence and prevalence of multivessels CHD.
- Trial name
- NCT03360981
- Testing
- Incretins
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Ischemic Stroke
Epicardial Adipose Tissue Volume and Attenuation in Acute Ischemic Stroke
Excessive accumulation or abnormal distribution of adipose tissue is a recognized risk factor for ischemic stroke. However, the impact of overweight or obesity on clinical outcomes of ischemic stroke is uncertain.
- Trial name
- EATVAS (NCT05631808)
- Testing
- Epicardial adipose tissue volume and attenuation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Subclinical Atherosclerosis
Adipose Visceral and Epicardial Risk Evaluation
The goal of this procedure-based interventional study without drugs or devices is to investigate the molecular mechanisms underlying metabolically unfavorable obesity and related clinical phenotypes, in order to identify…
- Trial name
- AVERE (NCT07504679)
- Testing
- Peripheral blood sampling
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Epicardial Fat, Obesity
CT Evaluation of Cardiovascular Risk Markers in Obese Patients
Obesity is a chronic metabolic disorder : it leads to coronary heart disease and early atherosclerosis. Coronary artery calcium measured by CT is known as a robust predictor to predict risk for cardiac events in symptomatic and…
- Conditions
- Epicardial Fat, Obesity, Cardiovascular Risks Markers, Metabolic Syndrome
- Trial name
- RisqOScan (NCT03111693)
- Testing
- Unenhanced Coro-CT
- Where
- France
- Volunteers
- 123 people
- Sponsor
- University Hospital, Clermont-Ferrand
Coronary Artery Disease
Characterization of Epicardial and Pericardial Adipose Tissue in Coronary Artery Disease
Human epicardial fat is the true visceral fat depot of the heart, and its regional distribution and physiology is of growing scientific and clinical interest.
- Trial name
- NCT02965625
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Atrial Fibrillation (AF), Arrhythmia
Computed Tomography of Pulse-Field Ablation
Radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) reduces left atrial (LA) volume post-ablation, a phenomenon termed reverse atrial remodeling, indicative of successful reversal of atrial cardiomyopathy…
- Trial name
- CT-PFA (NCT07395089)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabete Type 2, Unstable Angina
Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography
Calcification of the coronary arteries is a direct sign of atherosclerotic disease of the coronary arteries and has been shown to be a strong predictor of the risk of cardiovascular diseases, including myocardial infarction…
- Conditions
- Diabete Type 2, Unstable Angina, Myocardial Infarction, Diabetes Mellitus, Type 2
- Trial name
- NCT05998525
- Testing
- Dapagliflozin 10Mg Tab
- Where
- Mexico
- Volunteers
- 54 people
- Sponsor
- Hilda Elizabeth Macías Cervantes
Epicardial Fat, Visceral Fat
Epicardial Fat, Visceral Fat and Coronary Atherosclerosis
Background: Visceral fat is increasingly associated with metabolic syndrome and with fatty liver, a condition carrying a high risk of cardiovascular disease.
- Conditions
- Epicardial Fat, Visceral Fat, Atherosclerosis
- Trial name
- NCT01344694
- Testing
- patient with liver fat, pts. with excess of visceral fat, control
- Where
- Israel
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Metabolic Syndrome
Conjugated Linoleic Acid / Leucine Versus Metformin on Visceral Fat in Metabolic Syndrome
In Mexico, obesity is a major public health problem. In recent years he has presented a considerable increase in the population.
- Trial name
- NCT02629627
- Testing
- Conjugated linoleic acid/Leucine, Metformin
- Volunteers
- 104 people
- Sponsor
- Centro Universitario de Ciencias de la Salud, Mexico
Coronary Artery Disease
The Effect of SGLT-2 Inhibitors on Epicardial Adipose Tissue and Cardiac Function in T2DM Patients With CAD (EpiCAD)
Sodium-glucose contrasporter-2 (SGLT-2) inhibitors make up an antidiabetic medication that promotes glycosuria. They are known to have an indirect reduction in cardiovascular complications, based on a series of in-depth studies.
- Trial name
- EpiCAD (NCT06128096)
- Testing
- Sodium Glucose Co-transporter 2 (SGLT2) Inhibitor
- Where
- Malaysia
- Volunteers
- 360 people
- Sponsor
- Clinical Research Centre, Malaysia
Heart Failure With Preserved Ejection Fraction
Association of Epicardial Adipose Tissue Volume Axnd Radiodensity With Coronary Artery Calcification in Patients With HFpEF
Recruiting patients who were diagnosed with HFpEF. Using Non-contrast CT to measure the total Agatston coronary artery calcification score, epicardial adipose tissue volume and attenuation. Analysing the correlation between them.
- Trial name
- NCT05556785
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chongqing Medical University
Heart Failure With Preserved Ejection Fraction
The Relationship Between Epicardial Fat Tissue and Cardiac Function in HFpEF Patients
Heart failure with preserved ejection fraction (HFpEF) refers to a group of symptoms and signs of heart failure, normal or near-normal left ventricular systolic function (EF>50%), and ventricular muscle diastolic dysfunction and…
- Trial name
- NCT05068934
- Where
- China
- Volunteers
- 1,083 people
- Sponsor
- Dongying Zhang
Coronary Atherosclerosis, Adipokines
Adipokines of Epicardial Adipose Tissue and Atherosclerosis of Coronary Arteries
The aim of the study is to investigate whether the expression and production of adipokines secreted by the epicardial adipose tissue correlate with the degree of coronary atherosclerosis.
- Trial name
- NCT03322332
- Where
- Greece
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Monoclonal Gammopathies, Overweight
Antigen-Lipid-Driven Monoclonal Gammopathies Targeting Epicardial Fat
The purpose of this research study is to learn about the effect of Liraglutide (Victoza) on the fat of the heart and some fat cells in blood.
- Conditions
- Monoclonal Gammopathies, Overweight, Obesity
- Trial name
- NCT02920190
- Testing
- Liraglutide
- Sponsor
- University of Miami
Heart Failure, Metabolic Cardiovascular Syndrome
Cardiometabolic evalUation REgistry of Heart Failure
This is a combined retrospective-prospective observational cohort study investigating the role of systemic and local cardiometabolic risk factors in cardiac structural/functional remodeling and clinical outcomes among heart…
- Conditions
- Heart Failure, Metabolic Cardiovascular Syndrome, Metabolic Diseases
- Trial name
- CURE-HF (NCT06939985)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Ruijin Hospital
Myocardial Infarction
Prediction of Coronary Artery Disease Severity by Epicardial Adipose Tissue Thickness
is to test the hypotheses that epicardial adipose tissue can be a marker of severity of coronary artery disease in myocardial infarction patients
- Trial name
- NCT03308539
- Testing
- echocardiography and cardiac magnetic resonance
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Osama Fekry
Type2 Diabetes Mellitus
Relation of Epicardial Fat and Diabetic Nephropathy in Egyptian Patients
The heart and vessels are surrounded by layers of adipose tissue, which is a complex organ composed of adipocytes, stromal cells, macrophages, and a neuronal network, all nourished by a rich microcirculation.
- Trial name
- NCT03470415
- Volunteers
- 100 people
- Sponsor
- Assiut University
Ankylosing Spondylitis
Epicardial Adipose Tissue Thickness and the Related Factors in Patients With Ankylosing Spondylitis
The aim of this study was to assess the EATT and the related factors in patients with AS and to compare the results with that of the healthy controls'
- Trial name
- NCT06094686
- Testing
- epicardial adipose tissue thickness
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Heart Failure with Preserved Ejection Fraction
Dapagliflozin in Reducing Epicardial Adipose Tissue in Heart Failure with Preserved Ejection Fraction
Heart failure with preserved ejection fraction (HFpEF) is becoming the most common cause of heart failure worldwide, in part, driven by a rising prevalence of obesity.
- Trial name
- NCT06510270
- Testing
- Dapagliflozin 10 mg once daily, Loop diuretics, Treatments of associated co-morbidities (e.g Anti-hypertensive, oral hypoglycemic)
- Volunteers
- 70 people
- Sponsor
- Aswan University
Obesity
Bariatric Surgery and Epicardial Adipose Tissue: a MRI Study
The aim of this study is to measure the volume of the epicardial adispose tissue (EAT) and other morphological and functional cardiovascular parameters in subjects with severe obesity, using an open magnetic resonance unit…
- Trial name
- NCT03273621
- Testing
- Bariatic surgery
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- IRCCS Policlinico S. Donato