Clinical trials: Epidemic Disease
HIV Infections
ETE Interventions in the Dental Setting
The purpose of this study is to use information technology (IT) to support the delivery of HIV prevention and care best practices in the dental care setting to meet the Department of Health and Human Services (DHHS) Ending the…
- Trial name
- NCT05584501
- Testing
- Care Navigator, Health Information Supported Ending the HIV Epidemic (ETE) Activities in Dental Setting
- Where
- 2 sites in United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Columbia University
Meningitis, Meningococcal
Ciprofloxacin for the Prevention of Meningococcal Meningitis
This study evaluates the effect of antibiotic prophylaxis with ciprofloxacin, given to the contacts of meningitis cases, on the overall attack rate of meningitis during an epidemic.
- Trial name
- NCT02724046
- Testing
- Ciprofloxacin
- Where
- Niger
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Epicentre
Kawasaki Disease
Kawasaki Disease During the COVID-19 Epidemic
Northern Italy is the second region hit by the SARS-COV2 infection worldwide. Data on COVID-19 clinical presentation in children is still scarce, but fewer rate of infection and milder disease seem typical of this age group.
- Trial name
- KAWACOVID (NCT06309303)
- Testing
- Clinical evaluation
- Where
- 4 sites in Italy
- Volunteers
- 25 people
- Sponsor
- IRCCS Burlo Garofolo
Cryotherapy Effect, Compression
Combined Cryotherapy With Compression Versus Cryotherapy Alone After Orthopaedic Surgery
Cryotherapy has been used to enhance recovery after orthopaedic surgery. Many devices are available but few can guarantee a temperature regulation during a prolonged time and therefore have been criticized.
- Conditions
- Cryotherapy Effect, Compression, Postoperative Pain Management
- Trial name
- NCT05011084
- Testing
- Game Ready Cryotherapy with Compression Group, Control Cryotherapy Group
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- Walter Reed National Military Medical Center
Allergy to Peanut
Predictors of Persistent Peanut Allergy at Age 5 Years
The purpose of this study is to determine if avoidance of peanut by children with positive allergy testing to peanut in the first 5 years of life increases the likelihood of developing a persistent peanut allergy by age 5 years.
- Trial name
- NCT02497261
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Emergency Medicine
Healthcare Renunciation During the Confinement Period in Connection With the COVID-19 Epidemic in Adult Emergency Departments
Healthcare renunciation is defined as: "Individuals give up care when they do not seek services and health care professionals when they experience a disorder, experience a physical or mental disorder, or when they do not access…
- Trial name
- NCT04460196
- Testing
- survey
- Where
- 2 sites in France
- Volunteers
- 900 people
- Sponsor
- University Hospital, Angers
Adenoviral Keratoconjunctivitis
Adenovirus Keratoconjunctivitis and Ophtalmology
Adenovirus conjunctivitis is an epidemic disease registered as a common occupational disease for ophthalmologists and orthoptists. It can leave corneal sequelae even several years after infection.
- Trial name
- ADV-OPH (NCT04417244)
- Where
- France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Naloxone
Nalox-Comm: Naloxone Communication Training for Pharmacists
This is a pilot Randomized Controlled Trial (RCT) in which 120 pharmacists will be randomized to an experimental or control group and data on naloxone dispensing and secondary outcomes will be collected over the course of the RCT.
- Trial name
- Nalox-Comm (NCT04677387)
- Testing
- Nalox-comm Training Module, Prescribe to Prevent: Overdose Prevention and Naloxone Rescue Kits for Prescribers and Pharmacists
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Childhood Obesity
Wellness Action Plan Trial Addressing Childhood Obesity
The objective of this study was to determine the effectiveness of a novel Wellness Action Plan aimed at 1) improving parent recall of diet and activity plans 2) increasing follow-through with plans and 3) aiding parents in…
- Trial name
- NCT02185248
- Testing
- Wellness Action Plan
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Roohi Kharofa, MD, MPH
Covid19, SARS-CoV Infection
Assessment of the Prevalence and the Impact of the COVID-19 Epidemic in the French Flight Crew in 2020
The aeronautical community was also affected and greatly impacted economically and socially by the Covid-19 pandemic. Away from the acute phase, the epidemiological impact and the consequences of this disease within the French…
- Trial name
- Covaé (NCT04514874)
- Testing
- Questionnaire
- Where
- 2 sites in France
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
HIV Infections
Getting to Zero Among HHI MSM in the American South
This study will evaluate a status-neutral integrated strategy to improve access to and uptake of HIV prevention and treatment services for the highest HIV incidence (HHI) men who have sex with men (MSM) in participating…
- Trial name
- NCT05075967
- Testing
- Health Access Coalitions, Social Media, Peer Support
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- HIV Prevention Trials Network
Viral Conjunctivitis
Therapeutic Efficacy of APD-209 Eye Drops in Treatment of Epidemic Keratoconjunctivitis (EKC)
A randomized, double-masked, placebo-controlled, multi-centre phase IIa proof-of-concept study to evaluate efficacy and safety of APD-209 Eye drops for treatment of acute phase adenovirus-induced EKC.
- Trial name
- NCT01977443
- Testing
- APD-209 Eye drops
- Where
- 10 sites in Germany, Poland and 1 more
- Volunteers
- 47 people
- Sponsor
- Adenovir Pharma AB
Viral Conjunctivitis
Treatment of Epidemic Keratoconjunctivitis With 2% Povidone-iodine
The purpose of this study is to determine the outcomes of treating epidemic keratoconjunctivitis with 2% povidone-iodine.
- Trial name
- NCT01179412
- Testing
- 2% povidone-iodine
- Where
- Thailand
- Volunteers
- 172 people
- Sponsor
- Mahidol University
Human Immunodeficiency Virus (HIV)
e-HERO: Ending the HIV Epidemic in Rural Oklahoma
The goal of this study is to increase HIV and syphilis testing and linkage to care, increase condom use, and promote PrEP uptake among sexual minority men (SMM) and American Indian (AI) men in rural Oklahoma, a state that is an…
- Trial name
- e-HERO (NCT05664802)
- Testing
- e-HERO: Ending the HIV Epidemic in Rural Oklahoma
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Epidemic Kaposi's Sarcoma, Recurrent Kaposi's Sarcoma
Interleukin-12 in Treating Patients With AIDS-Related Kaposi's Sarcoma
RATIONALE: Interleukin-12 may kill tumor cells by stopping blood flow to the tumor and by stimulating a person's white blood cells to kill their tumor cells.
- Trial name
- NCT00019188
- Testing
- interleukin-12
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
BPPV, Benign Paroxysmal Positional Vertigo
Clinical Trial of Vit D and Calcium for Recurrent BPPV
Randomized double blind placebo controlled trial of vitamin D supplements, with or without calcium supplementation, versus placebo in reduction of recurrences in BPPV.
- Conditions
- BPPV, Benign Paroxysmal Positional Vertigo, Vertigo, Vertigo, Peripheral
- Trial name
- NCT05863949
- Testing
- vitamin D +/- calcium
- Volunteers
- 860 people
- Sponsor
- Ottawa Hospital Research Institute
RSV Infection
Impact of the Covid-19 on Respiratory Syncytial Virus (RSV) Epidemic
The magnitude of seasonal Respiratory Syncytial Virus (RSV) epidemics brings each year new logistical challenges for the hospitalization of young infants with bronchiolitis that overwhelm hospital capacities and lead to specific…
- Trial name
- IPCoVRS (NCT04944160)
- Testing
- Medical records analysis, Comparison of cohorts
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
HIV
SEARCH SAPPHIRE Phase B
This study will evaluate the effects of optimized dynamic prevention and treatment packages delivered in a precision community health model on HIV incidence, as well as other health outcomes, in a community randomized trial…
- Trial name
- NCT05768763
- Testing
- Community-enhanced reach activities, Person-centered care delivery, Data system enhancement to improve reach and person-centered delivery
- Where
- 2 sites in Kenya, Uganda
- Volunteers
- 81,952 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Rhinovirus, RSV Infection in Children Less Than 5 Years of Age
Impact of the Covid-19 on RSV Epidemic in the Metropolis of Lyon
The magnitude of seasonal RSV epidemics brings each year new logistical challenges for the hospitalization of young infants with bronchiolitis that overwhelm hospital capacities and lead to specific winter plans with…
- Trial name
- IPCoVRS-2 (NCT05348655)
- Testing
- epidemiology
- Where
- 2 sites in France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
Cutaneous Leishmaniasis
Frequency of Parasite Infection in Hyraxes and Sandflies During Outbreak of Leishmania Tropica Epidemic in The West Bank
The objective of the project is to study the pathogenesis of Leishmania tropica infection in a focus of infection, to learn about relationship of infection in humans with ecological factors such as infection in hyraxes reservoir…
- Trial name
- NCT00737386
- Where
- Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization