Clinical trials: Epidural/Anesthesia
Effects of Anesthesia Spinal and Epidural in Pregnancy
Air Versus Saline Solution for the Localization of the Epidural Space in Labour Analgesia
Epidural space localization using loss of resistance technique with air (ALOR) is controversial in obstetric analgesia due to a minor efficacy and risk of complications, compared with loss of resistance technique with saline…
- Trial name
- NCT02792933
- Testing
- air in epidural space, saline in epidural space
- Volunteers
- 400 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Pain, Postoperative
PIEB-PCEA vs CEI-PCEA for Abdominal Oncological Surgery. A Randomized Prospective Clinical Trial
The aim of the study is to compare programmed intermittent bolus application and continuous epidural infusion with regard to additionally applied patient-controlled volume of local anesthesia and quality of analgesia.
- Trial name
- PIEB (NCT03378804)
- Testing
- Programmed intermittent epidural bolus application (PIEB), Continous epidural analgesia
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- Philipps University Marburg
Epidural Catheter, Post Operative Pain
Is Tunneling Effective in Preventing Failure of Epidural Analgesia? A Randomized Trial
This is a prospective randomized single blinded study in patients planned to undergo general anesthesia and epidural catheter insertion for pain control after abdominal, thoracic and orthopedic surgery.
- Trial name
- NCT03706352
- Testing
- tunneling epidural catheter
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- King Hussein Cancer Center
Labor
Effect of Epidural Dexamethasone on Labor Analgesia
The purpose of this study is to detect whether the addition of epidural dexamethasone will prolong labor analgesia.
- Trial name
- NCT02665936
- Testing
- Levobupivacaine, Dexamethasone and levobupivacaine, Levobupivacaine and Dexamethasone
- Volunteers
- 90 people
- Sponsor
- Kasr El Aini Hospital
Hypotension After Neuraxial Anesthesia, Cesarean Section
Comparing Spinal, Epidural, and Dural Puncture Epidural Anesthesia for Cesarean Delivery: Hemodynamics and Block Quality
The goal of this clinical trial is to compare three regional anesthesia techniques (spinal, epidural, and dural puncture epidural anesthesia) in healthy pregnant women undergoing planned (elective) cesarean delivery.
- Conditions
- Hypotension After Neuraxial Anesthesia, Cesarean Section, Anesthesia, Obstetrical, Post-Dural Puncture Headache
- Trial name
- NCT07883733
- Testing
- Spinal Anesthesia, Epidural Anesthesia, Dural Puncture Epidural Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Labor Pain, Nociceptive Pain
Nociception Level Index (NOL Index) for Obstetrical Pain Assessment Under Epidural Analgesia.
Pain has been defined by the International Association for the Study of Pain (IASP) as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage".
- Conditions
- Labor Pain, Nociceptive Pain, Epidural Analgesia, NOL Index
- Trial name
- NCT05898737
- Testing
- NOL-Index
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Cesarean Section, Epidural; Anesthesia
Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor
The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia.
- Trial name
- NCT04074005
- Where
- Thailand
- Volunteers
- 188 people
- Sponsor
- Mahidol University
Hypospadias, Postoperative Pain
Comparison of Sacral ESP Block and Caudal Block in Pediatric Hypospadias Surgery
Hypospadias surgery in pediatric patients requires effective postoperative analgesia to ensure patient comfort and reduce perioperative stress.
- Trial name
- NCT07619651
- Testing
- Sacral ESP Block, Caudal Epidural Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Anesthesia; Adverse Effect, Spinal and Epidural, Headache, Complications; Anesthesia, Spinal and Epidural, in Pregnancy
Comparison of Two Spinal Needles Regarding Postdural Puncture Headache
The aim of the study is to observe the rate of postdural puncture headache observed after spinal anesthesia in cesarean section patients. Two kind of spinal anesthesia needles will be used: 1.
- Trial name
- NCT01821807
- Where
- Turkey (Türkiye)
- Volunteers
- 256 people
- Sponsor
- Adiyaman University Research Hospital
Cesarean Section
Fluid Management for Cesarean Section
Cesarean section-associated hypotension is one of the pivotal factors to influence the Apgar Score of children and related with the stable hemostasis during the whole process of labor.
- Trial name
- FMCS (NCT00488111)
- Testing
- Ringer's Lactate, 6% Starch
- Where
- China
- Volunteers
- 850 people
- Sponsor
- Nanjing Medical University
Surgical Complications From General Anesthesia, Cerebral Ischemia
Measurement of the Cerebral Saturation for Assessment of Safety of Epidural Anaesthesia During Abdominal Surgery
Subsequent and non-randomised patients, adult patients qualified for major abdominal surgeries were enrolled
- Conditions
- Surgical Complications From General Anesthesia, Cerebral Ischemia, Anesthesia; Reaction
- Trial name
- NCT03161275
- Where
- Poland
- Volunteers
- 101 people
- Sponsor
- Jagiellonian University
Free Tissue Flaps
Effect of Epidural Anesthesia on Blood Flow in Arterial Anastomosis of Free Flap
Comparing the changes of arterial anastomotic blood flow between general anesthesia alone and general anesthesia with epidural anesthesia in patients who undergoing free flap transposition using Duplex ultrasound.
- Trial name
- NCT03330808
- Testing
- Epidural anesthesia
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Postoperative Pain
Association of Different Doses of Clonidine in Caudal Epidural Anesthesia for Hypospadias Surgery
The use of increasing doses of clonidine ssociated to bupivacaine in caudal epidural block provides better postoperative analgesia compared whit analgesia provide by bupivacaine alone It is a randomized, double blind study…
- Trial name
- clonidine (NCT02769390)
- Testing
- Clonidine 1 mcg/Kg, Clonidine 2 mcg/ Kg, Clonidine 3 mcg/ Kg
- Volunteers
- 80 people
- Sponsor
- Federal University of Minas Gerais
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women in spontaneous labor with whom analgesia is maintained with a combined spinal epidural (CSE)…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982838
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Labor Pain
Identification of the Sensory Level Block to Cold During Epidural Analgesia for Labor: A Cohort Study to Determine the Influence of the Direction of Testing
Assessment of the upper sensory block level during neuraxial analgesia for labor and delivery is an essential component of clinical management and patient safety.
- Trial name
- NCT03572439
- Testing
- Sensory block level check using ice
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Urinary Retention
Urinary Retention After Vaginal Delivery With Epidural Anesthesia.
The investigators intend to compare the rate of urinary retention among female patients after vaginal delivery under epidural anesthesia, depending on bladder catheterization type, either by a foley catheter inserted adjacent to…
- Trial name
- NCT02865551
- Testing
- Foley catheter, Short term catheter, Epidural anesthesia
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Rambam Health Care Campus
Pain, Postoperative, Adverse Reaction to Epidural Anesthesia
Pediatric Caudal Anesthesia Block. And Pain Control
Caudal epidural block CEB is the most commonly performed neuraxial block to provide effective pain relief and analgesia in patients undergoing infra-umbilical pediatric surgery.
- Conditions
- Pain, Postoperative, Adverse Reaction to Epidural Anesthesia, Anesthesia, Caudal
- Trial name
- CEB (NCT05581940)
- Testing
- Group A Caudal Epidural Anesthesia with bupivacaine 0.25% and group B with opioid intervenors
- Where
- Bahrain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Acute Postoperative Pain
Ultrasound Guided Bilateral Erector Spinae Block Versus Caudal in Lumbar Spine Surgeries
Major lumbar spine surgeries are associated with severe postoperative pain that usually lasts for at least 3 days.Caudal epidural analgesia has a crucial role in providing effective pain relief post lumbar spine surgeries by…
- Trial name
- NCT05351203
- Testing
- caudal block, Erector spinae block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative
Erector Spinae Plane Block (ESP) Versus Thoracic Epidural Anesthesia in Video-Assisted Thoracoscopic Surgery (VATS) in Pediatric Population; a Randomized, Controlled Study
Aim of the study is to investigate the efficacy and safety of continuous ESP block in children under the age of 10 yrs undergoing video-assisted thoracoscopic procedures, compared to Thoracic Epidural Anesthesia (TEA).
- Trial name
- ESP (NCT04878341)
- Testing
- Erector Spinae Plane Block
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- Vittore Buzzi Children's Hospital
Pregnancy Related, Epidural; Anesthesia, Headache
Inertial Sensors for Obstetrical Walking Epidural Tracking
Freedom of movement and the ability to walk are crucial during the first stage of labor, potentially reducing labor duration, cesarean section risk, epidural analgesia use, and bladder catheterization.
- Conditions
- Pregnancy Related, Epidural; Anesthesia, Headache, Labor Complication
- Trial name
- MOTION-EASE (NCT06471790)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon