Clinical trials: Epidural/Anesthesia
Pulmonary Function
Post-operative Pulmonary Function After Kidney Surgery Under Two Different Techniques
To assess the respiratory and analgesic effects of continuous thoracic paravertebral block versus thoracic epidural in patients undergoing kidney surgery
- Trial name
- NCT03885583
- Testing
- thoracic epidural block, paravertebral block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Labor Epidural Analgesia
Comparative Study of the Combination of Different Modes of Administration of Local Anesthetics in Labor Analgesia
The investigators have design an observational study to know the anesthetic consumption in terms of rescue analgesia (Patient Controlled Epidural Analgesia (PCEA) and manual boluses) of the combination of different modes of…
- Trial name
- NCT03839056
- Testing
- IC+PIEB+PCEA high flow, PIEB+PCEA high flow, PIEB+PCEA standar flow
- Where
- Spain
- Volunteers
- 151 people
- Sponsor
- Marian Daras
Cesarean Section, Affecting Fetus or Newborn
Dexmedetomidine for Cesarean Section
Current cesarean section often chooses spinal anesthesia. And in order to avoid the impact of drugs on the fetus, before the delivery, anesthesiologist generally don't use sedative or analgesic drugs.
- Trial name
- NCT02715154
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Inguinal Hernia, Circumcision
Analgesia in Children Using Caudal Epidural Ropivacaine
Caudal epidural analgesia (caudal block)is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et al…
- Trial name
- NCT01494272
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Labor, Second Stage
Urinary Catheterization and Second Stage of Labor
Labor is divided into three stages: the first stage is from labor onset until full dilation, second stage is from full dilation until delivery of the baby, and the third stage from the delivery of the baby until the delivery of…
- Trial name
- cath2stage (NCT02198157)
- Testing
- urinary catheterization
- Where
- Israel
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Raed Salim
Ketamine Adverse Reaction, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Does a Single Intravenous Dose of Ketamine Reduce the Need for Supplemental Opioids in Post-Cesarean Section Patients?
Pain control after cesarean delivery is associated with improved breastfeeding and infant rooming-in times. In addition, inadequate analgesia leads to elevated plasma catecholamine concentrations, which negatively affect every…
- Conditions
- Ketamine Adverse Reaction, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy, Complication of Labor and/or Delivery
- Trial name
- NCT00486902
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- Northwestern University
Anesthesia; Adverse Effect, Spinal and Epidural, Anaesthetic Complication Neurological
Neurotoxicity of Spinal Anesthesia With Ropivacaine and Bupivacaine
Consenting patients, scheduled for orthopaedic surgery under spinal anesthesia will be randomly assigned (1:1) to receive ropivacaine or bupivacaine as a single shot before the start of surgery, followed by bolus doses of the…
- Trial name
- BuRoNe (NCT03293472)
- Testing
- Ropivacaine, Bupivacaine
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- University of Rzeszow
Anesthesia,Obstetrical
Palpation and ACCURO for Placing Spinal in C-section
The Accuro is a three dimensional handheld ultrasound device. This device uses sound waves to create pictures of the spine in three dimensions.
- Trial name
- NCT03090295
- Testing
- Palpation and Accuro
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Virginia
Labor Pain
CSE for Labour Analgesia: A Comparison of Two Intrathecal Regimens
Analgesia in labour is not readily available in many parts of Sub-Saharan Africa. The overall cost of Epidural services in terms of human personnel and financial implication makes this inaccessible to many women in labour.
- Trial name
- SSS (NCT03117595)
- Testing
- Bupivacaine-fentanyl, Bupivacaine-fentanyl morphine
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Beckley
Cesarean Section Complications
Effect of Three Weight-adjusted Vasopressors for Elective Cesarean Delivery
This study compared the effects of prophylactic infusion of metaraminol, phenylephrine and norepinephrine adjusted according to body weight on fetal acid-base balance and maternal hemodynamics.
- Trial name
- NCT04991662
- Testing
- metaraminol, Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Epidural; Anesthesia
Does Ultrasound Increase the First-pass Success of Epidural Space Identification in Obese Parturients
Obesity is associated with difficulties in epidural space catheterization. The investigators want to prove that a pre-procedural ultrasound exam of lumbar spine increase the first-pass success rate of the epidural space…
- Trial name
- NCT04352283
- Testing
- Preprocedural ultrasound exam of lumbar spine
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Caen
Spinal Stenosis Lumbar, Disk Herniated Lumbar
A Comparison of Intravascular Injection With Chiba Needle and Whitacre Needle
Caudal epidural injection (CEI) is effective for spinal pain. However, intravascular injection may occur during CEI, which can lead to hematoma, neurologic deficit and local anesthetics systemic toxicity.
- Trial name
- NCT04204720
- Testing
- needle (Chiba), needle (Whitacre)
- Where
- South Korea
- Volunteers
- 164 people
- Sponsor
- Kyungpook National University Hospital
Postoperative Pain, Inflammatory Response
Bilateral Ultrasound Guided Quadratus Lumborum Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response in Abdominal Surgery
This study aims at comparing the effects of bilateral ultrasound-guided quadratus lumborum block versus lumbar epidural block on postoperative analgesia and inflammatory response following major lower abdominal cancer surgery.
- Trial name
- NCT03958942
- Testing
- Ultrasound quadratus lumborum block with bupivacaine 25%, lumbar epideural block with bupivacaine 25%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Epidural Analgesia, Hospital Follow-up
Obstetrical Analgesia in the Estaing Hospital Maternity. A Prospective Database to Study the Determinants of Labor Pain and the Resulting Maternal Non Satisfaction.
There is a trend to offer personalized care in many medical domains. In the field of labor pain, it appears that maternal satisfaction about care is multifactorial, and that labor pain is only one of its determinants, competing…
- Trial name
- AOMHE (NCT03314571)
- Testing
- analgesia for labor
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Clermont-Ferrand
Bolus Versus Infusion Ketamine, Anesthesia Gas Consumption
Comparison of BIS Index Variations: Bolus Versus Infusion Ketamine, and Impact on the Anesthesia Gas Consumption
The aim of the present study is to show that i.v. ketamine boluses might lead to significant and clinically relevant BIS index increase that might lead to an increase in anesthesia dosing (halogenous gas) when compared to an i.v.
- Trial name
- KETABIS (NCT03781635)
- Testing
- bolus of intravenous ketamine, continuous infusion of intravenous ketamine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Lung Diseases, Pain, Acute
TEA, ESB and Paravertebral Block During Single-lung Ventilation for Lung Resection
Thoracotomy operations are known to be painful surgical procedures, so providing effective intraoperative and postoperative analgesia is so important for all anaesthesiologists.
- Trial name
- NCT05211791
- Testing
- erector spinae block, paravertebral block anesthesia, Thoracic epidural anesthesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- South Egypt Cancer Institute
Parturient
Ultrasound Evaluation of Labor Epidural
To compare the labor epidural analgesic (EA) profiles between landmark insertion EA levels which are congruent and ingruent to ultrasound confirmation in lateral decubitus position.
- Trial name
- NCT04056403
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Hospital
Labor Pain, Pregnancy
Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
The purpose of this study in nulliparous women undergoing induction of labor is to determine whether initiation of neuraxial analgesia compared to systemic opioid analgesia early in labor (< 4 cm cervical dilation)affects the…
- Trial name
- NCT00380978
- Testing
- combined spinal epidural analgesia, late analgesia (systemic)
- Where
- United States
- Volunteers
- 1,026 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Coronary Artery Occlusion
Neuroaxial Prophylaxis for CABG
Investigators plan to study the effect of thoracic epidural analgesia on postoperative parameters (complication rate, duration of hospitalization, mortality, etc.) of coronary artery bypass grafting.
- Trial name
- NCT04244435
- Testing
- CABG, thoracic epidural analgesia, analgesia of opioids
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- Volgograd State Medical University
Colon Cancer, Anesthesia
General Anesthesia or Combined Spinal-epidural Anesthesia With Ketofol Sedation in Colon Cancer Surgery?
Anesthesia management in colon cancer surgery affects the postoperative mobilization, discharge and oral intake times of the patients.
- Trial name
- NCT05334251
- Testing
- combined spinal-epidural anesthesia
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent