Clinical trials: Epidural/Anesthesia
Pregnancy, Neonatal Hearing Function
Comparison of Different Anesthetic Techniques on Hearing Outcomes in Neonates After Cesarean Delivery
This is a single-center, prospective, single-blind randomized controlled trial. The investigators plan to recruit 144 pregnant women scheduled for cesarean delivery.
- Trial name
- ATHNCD (NCT07852624)
- Testing
- Combined spinal-epidural anesthesia, General Anesthesia (GA)
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Pre-eclampsia
Investigating the Novel Observation of Right-left Difference in Uterine Artery Vascular Resistance in Pre-eclampsia
The investigators previously demonstrated that epidural ropivacaine reduces uterine artery vascular resistance in a dose dependent manner in pre-eclampsia.
- Trial name
- NCT00848679
- Testing
- Epidural lidocaine, Epidural lidocaine 2%
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Epidural Anesthesia
Effect of Intraoperative Fluid Management on Morbidity
The purpose of this study is to determine whether intraoperative fluid and sodium restriction decreases postoperative morbidity
- Trial name
- NCT00156338
- Testing
- fluid management
- Where
- 3 sites in Germany
- Volunteers
- 108 people
- Sponsor
- University Hospital Muenster
Natural Childbirth, Water Birth
Effectiveness and Safety in Maternal and Neonatal Outcomes in Water Birth.
Childbirth is a unique and non-transferable experience in the life of a woman, her partner and her family. It is a very intense process that requires accompaniment and, in the vast majority of cases, requires analgesic support in…
- Conditions
- Natural Childbirth, Water Birth, Neonatal Asphyxia, Outcome, Adverse Birth
- Trial name
- NCT06429111
- Testing
- Epidural analgesia, Immersion water
- Where
- Spain
- Volunteers
- 642 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Sinus; Dermal, Pilonidal
Epidural and Spinal Anesthesia Techniques in Pilonidal Dermoid Sinus Surgeries
Pilonidal dermoid cyst surgery under general anesthesia and regional anesthesia techniques is used.regional anesthesia techniques; spinal, epidural, spinal epidural (combined) and is the local anesthesia.In the investigators…
- Trial name
- NCT02580500
- Testing
- epidural catheter, spinal catheter
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Pain
Determination of the Effective Volume of 0.125% Bupivacaine-fentanyl 5mcg/mL in Labour Epidurals
Different medications can be used as analgesics in labor epidurals. Bupivacaine is one of the most commonly used drugs for that purpose. The efficacy of a certain medication injected epidurally depends on the dose that is given.
- Trial name
- NCT01972269
- Testing
- Bupivacaine-fentanyl, Lidocaine
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anesthesia; Adverse Effect, Spinal and Epidural
Paramedian Incidence Angles in Spinal Anaesthesia
The objective here is to quantify the number of punctures and redirections during routine practice in the anesthesiology department, verify the final angle of incidence and the sac-skin distance by ultrasound, and determine the…
- Trial name
- NCT07210892
- Testing
- Measurement of needle insertion angles
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Consorci Sanitari de Terrassa
ERAS, Colorectal Surgery
Epidural Analgesia and Intraoperative Fluid Management in Colorectal Surgery
The Enhanced Recovery After Surgery (ERAS) protocols have demonstrated their efficacy in expediting recovery and minimizing postoperative complications, especially in patients undergoing abdominal surgery.
- Conditions
- ERAS, Colorectal Surgery, Goal-directed Fluid Therapy, Conventional Fluid Therapy
- Trial name
- NCT06810648
- Testing
- GDFT, GDFT/ED, CFT
- Where
- 2 sites in Greece
- Volunteers
- 121 people
- Sponsor
- University of Ioannina
Lung Cancer, Postoperative Pain
Paravertebral Block Versus Thoracic Epidural Analgesia
Thoracic epidural analgesia (TEA) is the basic method of analgesia in patients undergoing pulmonary lobectomy. TEA is considered to be a safe and thoroughly investigated method of pain relief that rarely causes serious…
- Trial name
- NCT04025606
- Testing
- Thoracic epidural, Paravertebral block
- Where
- Norway
- Volunteers
- 94 people
- Sponsor
- St. Olavs Hospital
Postoperative Pain
Comparison of Continuous ESP Versus TEA After Thoracotomy
This prospective, randomized, assessor-blinded study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided continuous erector spinae plane (ESP) block in patients undergoing thoracotomy.
- Trial name
- NCT05008614
- Testing
- Erector spinae plane block group, Thoracic epidural analgesia group
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Seoul National University Hospital
Labor Pain, Epidural Analgesia for Labour and Delivery
Early Labor Pre-Marking for Epidural Analgesia: Ultrasound vs Manual Palpation
The goal of this clinical trial is to learn if finding and marking the best spot on the back early in labor helps doctors perform epidural pain relief more successfully in pregnant women.
- Conditions
- Labor Pain, Epidural Analgesia for Labour and Delivery, Neuraxial Ultrasound
- Trial name
- NCT07669441
- Testing
- Preprocedural Spinal Ultrasound, Conventional Landmark Palpation
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Urodynamics, Acute Urinary Retention
Effects of Thoracic Epidural Anesthesia on Lower Urinary Tract Function
Acute urinary retention is one of the most common complications after surgery and anesthesia. Overfilling the bladder can stretch and damage the detrusor muscle, leading to atony of the bladder.
- Trial name
- NCT00790231
- Testing
- urodynamic procedure
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Labor for Induction Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women scheduled for an induction of labor, with whom analgesia is maintained with a combined spinal…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982851
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pulmonary Surgery
Erector Spinae Block, Epidural Analgesia and Intrathecal Analgesia in Thoracic Surgery
Pulmonary thoracic surgery is often responsible for severe postoperative pain, which is associated with an increase in postoperative morbidity and mortality.
- Trial name
- SPIRIT (NCT04147754)
- Testing
- Epidural anesthesia, Intrathecal morphine, Erector spinae block
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Pancreatic Cancer, Biliary Tract Neoplasms
Analgesic Efficacy After Pancreatobiliary Surgery: Intravenous Versus Patient-controlled Epidural
Prospective, single institute based, open label, double arm, randomized controlled trial Hypothesis: Pain control after resection of hepatobiliary tumors in patients with PCEA is more effective than in patients with IV-PCA.
- Trial name
- NCT04352023
- Testing
- Patient-controlled analgesia
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- National Cancer Center, Korea
Adult Patients, Total Knee Arthroplasty
Epidural Morphine for Postoperative Analgesia After Total Knee Arthroplasty
Single femoral nerve blockade combined with patient-controlled intravenous analgesia are used for postoperative analgesia for patients after TKA in the hospital of the investigators.
- Conditions
- Adult Patients, Total Knee Arthroplasty, Epidural Analgesia, Femoral Nerve Block
- Trial name
- NCT03203967
- Testing
- Epidural morphine, Single femoral nerve block, Intravenous morphine analgesia
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Peking University First Hospital
Cerebral Palsy, Hip Dysplasia
Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT06189781
- Testing
- Ropivacaine injection, Bupivacaine, lidocaine, ropivacaine
- Where
- 4 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Pleural Effusion, Malignant, Pleural Mesothelioma
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia
Video-assisted thoracic surgery (VATS) is usually performed with general anesthesia and single lung ventilation. However, performing thoracic surgery under awake regional anesthesia has several potential advantages including…
- Conditions
- Pleural Effusion, Malignant, Pleural Mesothelioma, Pleural Empyema, Pulmonary Diseases or Conditions
- Trial name
- VATS (NCT05077111)
- Testing
- Thoracic Epidural Anesthesia, General Anesthesia with One Lung Ventilation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mohamed Reda Ashour
Anesthesia
A Pilot Study to Investigate Plasma Bupivacaine Concentrations in Children Receiving Total Intravenous Anaesthesia and Caudal Analgesia
The objective of this pilot study is to compare plasma [bupivacaine] between two groups of paediatric patients under general anaesthesia who will all receive regional caudal anaesthesia with bupivacaine: group 1 will receive TIVA…
- Trial name
- NCT01216007
- Testing
- propofol, sevoflurane
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Epidural Anesthesia, Ultrasound
Different Type Ultrasound Guided Epidural Block Methods
The nerve blocks applied with ultrasonography are used for pain and operation after many operations today. Applications with ultrasonography shorten the processing time, reduce the amount of local anesthetic used and lead to…
- Trial name
- NCT04222192
- Testing
- Epidural block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital