Clinical trials: Epidural/Anesthesia
Thoracic Surgery
Comparison of Different Methods for Intra- and Postoperative Pain Therapy in Thoracic Surgery
The aim of the study is to determine which regional anaesthesiological technique (thoracic epidural analgesia or paravertebral block) is more suitable for thoracic surgery
- Trial name
- VERITAS (NCT05208619)
- Testing
- Regional anaesthesia
- Where
- 2 sites in Germany
- Volunteers
- 118 people
- Sponsor
- University Hospital, Bonn
Labor Pain
Use of Standardized Algorithm for the Management of Epidural Analgesia for Labor and Delivery
Programmed Intermittent Epidural Bolus (PIEB) has become a standard technique for labour analgesia in many departments of anesthesia.
- Trial name
- NCT04814199
- Testing
- Algorithm
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Abdominal Hernia, Abdominal Wall Defect
To Investigate the Use of a New Syringe "Visual Pressure Control (VPC)" for Epidural Anesthesia in Children Surgery
Pediatric epidural anesthesia has emerged as a safe and effective regional anesthesia technique for providing intraoperative and postoperative analgesia in thoracic and abdominal surgery.
- Conditions
- Abdominal Hernia, Abdominal Wall Defect, Abdominal Neoplasm, Urogenital Disease
- Trial name
- NCT05308771
- Testing
- VPC syringe
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Centre Hospitalier Universitaire de Tivoli
Hepatectomy
Effect of Epidural Anesthesia and Analgesia on Patients' Outcomes After Liver Resection
The purpose of this study is to analyze the effects of epidural anesthesia and analgesia on intraoperative clinical outcome, postoperative recovery, metabolic changes, and immune functions of the patients receiving open liver…
- Trial name
- NCT01617811
- Testing
- epidural anesthesia and analgesia
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Sir Run Run Shaw Hospital
Labor Onset and Length Abnormalities
Goal-directed Labor Epidural Analgesia Maintenance
The GLEAM trial is a multicenter, pragmatic, cluster-randomized trial to assess the effects of programmed intermittent epidural bolus versus continuous epidural infusion on the rate of spontaneous vaginal delivery and several…
- Trial name
- GLEAM (NCT05255263)
- Testing
- PIEB, CEI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Abdominal Neoplasms
Continuous Pre-peritoneal Wound Infiltration Versus Epidural Analgesia in Cancer Surgery
the investigators aim is to investigate the effect of continuous preperitoneal bupivacaine wound infiltration versus epidural analgesia on the inflammatory cytokines response following radical cytectomy
- Trial name
- NCT03002909
- Testing
- epidural catheter, preperitoneal catheter
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Pregnancy, Labor Pain
Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients?
The investigators are interested in determining the utility of ultrasound of the spine for labor epidurals or spinal anesthesia for women in labor or having a cesarean delivery.
- Trial name
- NCT01243216
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Labour Analgesia, Epidural Anaesthesia
An Observational Study Investigating the Positioning of Epidural Catheters and Their Function During Labour Analgesia
This is a small observational study investigating the physical changes that occur to epidural catheters after insertion for obstetric anaesthesia.
- Trial name
- NCT02924779
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rotkreuzklinikum München gGmbH
Hypospadias
Comparison of Analgesic Efficacy of Sacral Erector Spinae Plane Block and Caudal Epidural Block in Pediatric Patients Undergoing Hypospadias Surgery
The goal of this observational study is to learn about effects of block strategies (sacral erector spinae plane block - ESP, caudal block) on perioperative pain in pediatric patients undergoing hypospadias surgery.
- Trial name
- NCT07286786
- Testing
- Caudal Block Anesthesia, Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Labor Pain
Changes in Sensory Block Level During a Programmed Intermittent Epidural Bolus Regimen for Labor Analgesia: an Observational Cohort Study
Epidural analgesia is widely used for managing pain during labor. The programmed intermittent epidural bolus (PIEB) technique has been shown to produce less consumption of local anesthetics, better sensory block, less motor…
- Trial name
- NCT04716660
- Testing
- Sensory block level check
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Unplanned Caesarean Section
Chloroprocaine 3% - Epidural Anesthesia in Unplanned Caesarean Section
The study evaluate the quality of epidural anaesthesia and the safety of Chloroprocaine HCl 3% compared with Ropivacaine HCl 0.75% in patients with an epidural catheter in situ undergoing unplanned Caesarean section.
- Trial name
- NCT02919072
- Testing
- Chloroprocaine, Ropivacaine
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Sintetica SA
Spinal Anesthesia
Application of Unilateral Epidural Anesthesia in Older Patients With Hip Fracture
Because of population ageing, fragility fractures have become a huge burden on healthcare systems and wider society. Fractures result in a sharp drop in both short-term and long-term quality of life, they have a strong influence…
- Trial name
- NCT06093412
- Testing
- unilateral epidural anesthesia, combined lumbar and epidural anesthesia
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Sichuan Provincial People's Hospital
Cesarean Section, Anesthesia, Obstetrical
Dural Puncture Epidural With 27G vs 26G Needles Versus Standard Epidural for Elective Cesarean Delivery
The goal of this clinical trial is to learn whether the dural puncture epidural (DPE) technique shortens the onset time of surgical anesthesia compared with the standard epidural technique in healthy women undergoing elective…
- Conditions
- Cesarean Section, Anesthesia, Obstetrical, Anesthesia, Epidural
- Trial name
- NCT07897045
- Testing
- Standard Epidural Anesthesia, Dural Puncture Epidural With 27G Spinal Needle, Dural Puncture Epidural With 26G Spinal Needle
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ankara City Hospital Bilkent
Skin Bacteria
Comparing Skin Disinfectants Before Labour Epidural Analgesia
The purpose of this study is to compare the current standard skin disinfectant solution for labour epidurals used at BC Women's Hospital to another common skin disinfectant and to the skin disinfectant solution recommended by the…
- Trial name
- NCT00247897
- Testing
- Skin antisepsis
- Where
- Canada
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain, Postoperative
The Effect of Gabapentin on Thoracic Epidural Analgesia Following Thoracotomy
The purpose of this trial is to investigate the effect of gabapentin on thoracic epidural analgesia following thoracotomy, including assessment of both analgesia, pain intensity, pain quality and whether or not gabapentin…
- Trial name
- GABATEA (NCT01116583)
- Testing
- Gabapentin
- Where
- Denmark
- Volunteers
- 104 people
- Sponsor
- University of Aarhus
Hysterectomy
Effect of Enhanced Recovery After Surgery (ERAS) on Inflammatory Response After Planned Abdominal Hysterectomy
The aim of study is to determine effect of enhanced recovery after surgery (ERAS) on inflammatory response after abdominal hysterectomy.
- Trial name
- GERAS (NCT01747005)
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Antypin Eduard Eduardovich
Epidural Anesthesia, Laparoscopic Cholecystectomy
Comparison Epidural Anesthesia and General Anesthesia in Laparoscopic Cholecystectomy
Comparison of epidural anesthesia and general anesthesia for laparoscopic cholecystectomy, patients in the surgery and the effectiveness of anesthesia after surgery, the incidence of side effects or complications, and…
- Trial name
- NCT01398683
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Gestational Diabetes Mellitus in Pregnancy, Diet- Controlled
Maternal Glucose, Cortisol, and Neonatal Outcomes With and Without GDM
This study will compare maternal blood glucose and cortisol responses and neonatal outcomes between women with gestational diabetes mellitus and women without gestational diabetes mellitus who receive epidural analgesia during…
- Trial name
- NCT07870629
- Where
- 3 sites in Vietnam
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
Laparotomy
Influence of Analgesic Technique on Post Operative Rehabilitation After Median Laparotomy
Randomized controlled trial (1:1) in two parallel groups, multicentric, open-label, comparing two locoregional anesthesia (LRA) techniques as integral parts of multimodal analgesia: the control group will benefit from epidural…
- Trial name
- QORRECTCATH (NCT04985695)
- Testing
- Epidural analgesia, Bilateral rectus sheath block, Laparotomy
- Where
- 2 sites in France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Epidural Anesthesia, Labor Pain
Epidural Dexmedetomidine vs Nalbuphine for Labor Analgesia
The aim of this study is to compare epidural dexmedetomidine vs nalbuphine added to bupivacaine in labor analgesia and determine the privilege of one over the other and to compare the effect of both analgesics after delivery.
- Trial name
- NCT05327088
- Testing
- Dexmedetomidine, Nalbuphine
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University