Clinical trials: Epidural/Anesthesia
Pregnancy
Three-Dimensional Ultrasound (3D US) in Parturients
The purpose of this study is to compare accuracy of a new three-dimensional ultrasound (3D US) technique with the traditional palpation method for identification of the needle insertion site on patients' skin before epidural…
- Trial name
- NCT01523249
- Testing
- Lumbar 3D ultrasound scanning and palpation (Ultrasonix )
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Pain
Breakthrough Pain Computer Integrated Patient Controlled Epidural Analgesia
The computer-integrated patient controlled epidural analgesia (CIPCEA) system can automatically adjust the background infusion rate during combined spinal-epidural (CSE) analgesia based on the parturient's need as labour…
- Trial name
- BTP (NCT02313571)
- Where
- Singapore
- Volunteers
- 350 people
- Sponsor
- KK Women's and Children's Hospital
Amputation Stumps
The Value of Adding Either Meperdine or Fentanyl to Clonidine-bupivacaine
The use of clonidine as an alternative to epidural opioids offers several potential benefits. Clonidine does not have respiratory depressant effects, and the incidence of vomiting and pruritus is less frequent compared with that…
- Trial name
- NCT02128451
- Testing
- Meperdine, Fentanyl
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Caudal Epidural Block
Estimation of Injection Volume for Caudal Epidural Block Using Dynamic US Imaging in Children
Caudal epidural block is the most commonly used technique for analgesia in pediatric patients. Although there are clinically used doses of local anesthetics for caudal epidural block, we do not know exactly how much levels are…
- Trial name
- NCT04039295
- Testing
- ultrasound guided caudal epidural block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Asan Medical Center
Pregnant Women>37SA
EpiConCES - Epidural Lidocaine for Conversion to CaEsarean Section
The need to resort to a midwifery course work in cesarean is a common practice. Epidural analgesia for labor analgesia is practiced in 90% of women in obstetric work, as when the cesarean decision is taken course work in practice…
- Trial name
- EpiConCES (NCT02895022)
- Testing
- Lidocaine 2% adrénalinée, Epidural catheter, Caesarean section
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Respiratory Physiology
Alternative Measurements of Cough Pressure and Effects of Epidural Anaesthesia on Cough Pressure
Pressure generated by cough is an expression of expiratory muscle strength. Cough pressure (Pcough) is usually measured with gastric and/or esophageal catheters, but these are often either inconvenient or uncomfortable for the…
- Trial name
- ESPIRATOS (NCT02957045)
- Testing
- Cough pressure measurement, Pcough
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Parc de Salut Mar
Caudal Epidural Block
Perfusion Index in Caudal Epidural Anasthesia
A caudal epidural block is among the most widely administered techniques of regional anesthesia in pediatric patients. It helps in reducing the intraoperative dose of inhalational anesthetic agent used for maintenance of…
- Trial name
- NCT06695520
- Testing
- Caudal epidural block
- Volunteers
- 54 people
- Sponsor
- Assiut University
Anesthesia, Epidural, Paraesthesia
Safety of Two Epidural Catheters in Thoracic Epidural Anaesthesia (TEA)
Primary Objective: The primary objective is to demonstrate that the safety of Perifix New is non-inferior to using Perifix Standard when applied for thoracic epidural anaesthesia.
- Trial name
- NCT00394459
- Testing
- Perifix Epidural Anaesthesia Catheter, Perifix Standard, Perifix New
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- Maastricht University Medical Center
Cholelithiasis
Comparing Epidural Versus General Anesthesia for LESS Cholecystectomies
This study is a prospective, comparative, controlled, blinded study that will enroll a total of 70 adults that will undergo elective laparoendoscopic single-site incision gallbladder removal.
- Trial name
- NCT03247257
- Testing
- General Anesthesia, Epidural Anesthesia
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Florida Hospital Tampa Bay Division
Postoperative Pain, Delirium - Postoperative
Analgesia Methods and Early Mobilization in Geriatric ICU Patients After Major Surgery
This study looks at how different pain-control methods affect how quickly older adults get out of bed and start moving again after major surgery.
- Conditions
- Postoperative Pain, Delirium - Postoperative, Frailty, Postoperative Care in Geriatric Intensive Care Patients
- Trial name
- NCT07709975
- Testing
- Systemic Opioid Analgesia (± Multimodal), Epidural Analgesia, Peripheral Nerve Block (± Multimodal)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Epidural Analgesia, Labor Pain
Dexmedetomidine-esketamine-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia
Sufentanil-ropivacaine combination is commonly used for epidural labor anesthesia, but is associated with some adverse events. Dexmedetomidine and esketamine, each has been effectively used for neuraxial anesthesia in combination…
- Conditions
- Epidural Analgesia, Labor Pain, Sufentanil, Dexmedetomidine
- Trial name
- NCT07145775
- Testing
- sufentanil-ropivacaine combination, dexmedetomidine-esketamine-ropivacaine combination 1, dexmedetomidine-esketamine-ropivacaine combination 2
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Postdural Puncture Headache
Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache
PDPH is a common problem after either intentional or unintentional Dural puncture. It is especially common in young female patients and in patients undergoing Lumbar Puncture using the typical kit containing large 20 gauge…
- Trial name
- PDPH (NCT02394457)
- Testing
- Cosyntropin, Epidural Blood Patch
- Volunteers
- 29 people
- Sponsor
- United States Naval Medical Center, San Diego
Anesthesia, Epidural
Using the CompuFlo® CathCheck™ System to Check Epidural Catheter Function Before Tubal Ligation: A Pilot Study
This pilot study evaluates the use of the CompuFlo® CathCheck™ System to assess labor epidural catheter function before reactivation for postpartum tubal ligation.
- Trial name
- NCT07720908
- Testing
- CompuFlo® CathCheck™ System Assessment
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Ohio State University
Anesthesia
The Effects of Combined Spinal-epidural Anesthetics During Labor
Women who fulfil the inclusion criteria and who intended to regional anesthesia will be randomized into the epidural anesthesia arm or to the spinal-epidural anesthesia arm.
- Trial name
- NCT04012450
- Testing
- Epidural anesthesia, spina-epidural anesthesia
- Volunteers
- 40 people
- Sponsor
- Rambam Health Care Campus
Low Back Pain Requiring Epidural Injection
Fluoroscopically-guided Epidural Block in the Midthoracic Region: A Comparison of Anterioposterior Versus Oblique View Approach
A comparison of anterioposterior versus oblique view approach method for fluoroscopically-guided epidural block in the midthoracic region.
- Trial name
- NCT02300714
- Testing
- oblique view approach
- Where
- South Korea
- Volunteers
- 2 people
- Sponsor
- Yonsei University
Anesthesia
Magnesium for Shivering in Epidural Lidocaine Deliveries
Magnesium has been shown to decrease the shivering experienced from neuraxial anesthesia. This study aims to investigate whether magnesium decreases the shivering experienced in parturients undergoing labor epidural anesthesia…
- Trial name
- Mag-SHIELD (NCT03439358)
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Educational Problems
The Efficacy of Biplane Versus Single Plane Ultrasound in Facilitating Caudal Epidural Anesthesia in Pediatric Patients.
Ultrasound guidance plays a pivotal role in caudal epidural block in pediatric patients. In comparison to conventional single-plane ultrasound, biplane ultrasound offers the advantage of providing simultaneous transverse and…
- Trial name
- NCT06319989
- Testing
- Biplane Ultrasound, Single plane ultrasound
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Analgesia
Comparison of Standard Epidural and Dural Puncture Epidural Analgesia in Open Gynecological Surgery Techniques
The aim of this study is to compare the effectiveness of standard epidural and dural puncture epidural analgesia techniques used under NOL guidance.
- Trial name
- NCT05408052
- Testing
- Dural Puncture Epidural (DPE), Standart Epidural
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis
Prospective Observation of the Fluoroscopy-guided Cervical Epidural Approach Using the Contralateral Oblique View
The aim of the present study is to investigate the safety and clinical utility of contralateral oblique view for fluoroscopic guided cervical epidural access.
- Conditions
- Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis, Cervical Radicular Pain, Herpes Zoster
- Trial name
- NCT04774458
- Testing
- Fluoroscopic-guided cervical epidural access
- Where
- South Korea
- Volunteers
- 439 people
- Sponsor
- Asan Medical Center
Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS)
Analgesic Effectiveness of SPSIPB Versus Thoracic Epidural and Systemic Opioid Analgesia After VATS (SPSIPB-VATS)
This prospective observational study aims to compare the postoperative analgesic effectiveness of three commonly used pain management strategies in video-assisted thoracoscopic surgery (VATS): Serratus Posterior Superior…
- Conditions
- Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS), Thoracic Epidural Analgesia, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- SPSIPB-VATS (NCT07238348)
- Volunteers
- 120 people
- Sponsor
- Karadeniz Technical University