Clinical trials: Epidural/Anesthesia
Hemodynamic Instability
Effect of Remazolam on Hemodynamics During Hepatectomy
There is high incidence of hemodynamic instability in patients undergoing hepatectomy with low central venous pressure, especially in general anesthesia combined with epidural anesthesia.
- Trial name
- NCT06565715
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Jun Zhang
Regional Anesthesia Morbidity, Ultrasonography
Ultrasound-guided Combined Spinal-epidural Anesthesia: Pre-procedure Versus Real-time Scan
The investigators will compare the success rate, the consumed time, the number of needle passing, the depth and angle of the needle, the anesthetic effect, complications, pain and patient's satisfaction between 'Real-time scan'…
- Trial name
- NCT03805958
- Testing
- realtime ultrasonography, prescan ultrasonography
- Volunteers
- 56 people
- Sponsor
- Seoul National University Hospital
Epidural Block in Axial Spondyloarthritis
Ultrasound Guided Epidural Block in Axial SPA
Study Design: A randomized, prospective, pilot, controlled trial. Setting: Rheumatology and rehabilitation department Minia University and Sohag University Objectives: To evaluate the effectiveness of caudal epidural injections…
- Trial name
- NCT04143165
- Testing
- Epidural block with lidocaine and triamcinilone
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Sohag University
Postoperative Pain, Analgesia
Intrathecal Morphine Versus Epidural Analgesia for Laparoscopic Colon Surgery
Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing…
- Conditions
- Postoperative Pain, Analgesia, Colorectal Cancer, Surgery
- Trial name
- NCT06881563
- Testing
- Intrathecal Morphine, Epidural Analgesia
- Where
- Croatia
- Volunteers
- 98 people
- Sponsor
- Meri Mirceta
Epidural Analgesia
Comparative Study Between Two Adjuvant Drugs to Bupivacaine for Post-operative Epidural Analgesia in Abdominal Surgeries
Epidural analgesia is associated with early postoperative mobilization and rehabilitation with minimally associated pain and discomfort.
- Trial name
- NCT05323214
- Testing
- Control Analgesic regimen, Fentanyl Analgesic regimen, Dexmedetomidine Analgesic regimen
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Low Back Pain, Mechanical
Impact of Epidural Anesthesia on Low Back Function
Back pain is a common complication after the use of epidural anesthesia in obstetric and non-obstetric surgeries and occurs in 30-45% of cases (Brown, 2005).
- Trial name
- NCT04759963
- Where
- 2 sites in Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- South Valley University
Awake, Thoracic Epidural Anesthesia
Awake Thoracic Epidural Anesthesia Versus General Anesthesia in Thoracotomy
This study aims to compare awake thoracic epidural anesthesia and general anesthesia in thoracotomy.
- Conditions
- Awake, Thoracic Epidural Anesthesia, General Anesthesia, Thoracotomy
- Trial name
- NCT06930183
- Testing
- Awake thoracic epidural anesthesia, General anesthesia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Cancer Debulking, Enlarged Uterus
Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy
To determine if opioid consumption postoperatively among patients undergoing non-emergent laparotomy by the gynecologic oncology service who receive intrathecal morphine with intraoperative lidocaine (IML) infusion are lower than…
- Conditions
- Cancer Debulking, Enlarged Uterus, Fibroid Uterus, Adnexal Mass
- Trial name
- NCT05017246
- Testing
- Bupivacaine, Morphine, Lidocaine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Washington University School of Medicine
Abdominal Pain, Abdominal Cancer
Analgesic Efficacy of Dexmedetomidine Added to Fentanyl in PCEA
Dexmedetomidine if add to patient controlled epidural analgesia for patients undergoing major abdominal cancer surgery may improve its effects.
- Trial name
- NCT03453424
- Testing
- TEA+DEX, TEA
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- South Egypt Cancer Institute
Epidural; Anesthesia, Epidural Analgesia
Pharmacokinetics of Sufentanil After Epidural Administration
Sufentanil is an opioid analgesics used in all groups of patients. It has one of the strongest effects among analgesic drugs. Sufentanil is widely-used because of its very quick onset, short duration of action, and better…
- Conditions
- Epidural; Anesthesia, Epidural Analgesia, Abdominal Surgery
- Trial name
- NCT06069219
- Testing
- Epidural administration of sufentanil
- Where
- 2 sites in Poland
- Volunteers
- 18 people
- Sponsor
- Poznan University of Medical Sciences
Postoperative Pain
Continuous Epidural Analgesia Versus Continuous Supra-Inguinal Fascia Iliaca Block in Total Hip Replacement Surgery
comparison of continuous epidural analgesia and ultrasound guided continuous supra-inguinal fascia iliaca compartment block after total hip replacement surgery
- Trial name
- S-FICB (NCT04196439)
- Testing
- continuous epidural analgesia, supra-inguinal fascia iliaca compartment block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Anesthesia, Epidural
Epidural Pressure Waveform Recordings by the CompuFlo® Cath-Checker System
The purpose of this single arm, open label study will be to evaluate whether the dwell time of the epidural catheter, patients' position, the presence of active labor contractions and the priming volume of the epidural catheter…
- Trial name
- NCT04240912
- Testing
- CompuFlo Epidural Computer Controlled System
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- European e-Learning School in Obstetric Anesthesia
Combined Spinal Epidural Anesthesia, Prilocaine
Spinal Prilocaine for Caesarian Sections
Prilocaine theoretically could provide faster onset because of its lower pKa (7,7) compared to bupivacaine (8,1). The primary objective of this prospective double blind randomized trial is to determine block onset of spinal…
- Conditions
- Combined Spinal Epidural Anesthesia, Prilocaine, Bupivacaine, Pain
- Trial name
- NCT03219086
- Testing
- combined spinal epidural anaesthesia, Prilocaine, Bupivacaine
- Where
- 3 sites in Belgium
- Volunteers
- 182 people
- Sponsor
- University Hospital, Antwerp
S1 Transforaminal Epidural Block
Comparison of Tuohy Needle and Quincke Needle During S1 Transforaminal Epidural Injection
Recently, Park et al. introduced a new technique for performing S1 TFESI using ultrasound. S1 TFESI using ultrasound can be considered to overcome the disadvantages of exposure to radiation.
- Trial name
- NCT05925439
- Testing
- Tuohy needle group, Quincke needle group
- Where
- South Korea
- Volunteers
- 284 people
- Sponsor
- Gangnam Severance Hospital
General Anesthesia
Effect of Thoracic Epidural Analgesia on Intravenous Closed-Loop Anesthesia
The association of general anesthesia and of thoracic epidural anesthesia is used in thoracic surgery with a demonstrated benefit on the risk of postoperative respiratory complications.
- Trial name
- Drone-APDT (NCT00627081)
- Testing
- remifentanil
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hopital Foch
Success Rate Under Segmental Epidural, Post Operative Pain
Segmental Epidural Anesthesia (SEA) V/S General Anesthesia for PCNL
Management of nephrolithiasis has been revolutionized by the advent of shock-wave lithotripsy (ESWL) and percutaneous nephrolithotomy (PCNL).
- Trial name
- AnesthesiaPCNL (NCT02878512)
- Testing
- PCNL under General Anesthesia, Segmental Epidural Anesthesia
- Volunteers
- 60 people
- Sponsor
- Maharashtra University of Health Sciences
Preeclampsia
The Effect of Epidural Anesthesia on the Optic Nerve Sheath Diameter in Preeclampsia
This study aims to assess the effect of epidural anesthesia on the optic nerve sheath diameter in parturients with preeclampsia.
- Trial name
- ONSD (NCT04095832)
- Testing
- Epidural anesthesia
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul National University Hospital
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Anesthesia; Adverse Effect, Spinal and Epidural, Hip Arthropathy
Comparison of Three Different Sitting Positions for Performing Combined Spinal-Epidural Anesthesia
In this prospective and randomized study, we aimed to compare the effect of of three sitting positions (the traditional sitting position (TSP), the harmstring stretch position (HSP), and the squatting position on the success rate…
- Conditions
- Anesthesia; Adverse Effect, Spinal and Epidural, Hip Arthropathy, Knee Arthropathy
- Trial name
- NCT03541798
- Testing
- positions of patients for combined spinal-epidural anesthesia, Combined spinal epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital