Clinical trials: Epidural/Anesthesia
Pain, Breast Diseases
Thoracic Combined Spinal Epidural Anesthesia for Breast Surgery
The aim of the study is to investigate the efficacy of the thoracic combined spinal epidural anesthesia in breast surgery.
- Trial name
- NCT04706247
- Testing
- thoracic combined spinal epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Antalya Training and Research Hospital
Patient Satisfaction, Confidence, Self
Optimal Method and Timing to Provide Information on Epidural and Spinal Anaesthesia for Primiparas
Expectant mothers can give birth to their child either by vaginal delivery or by a caesarean section (the latter can be planned or necessary during an emergency).
- Trial name
- NCT04283721
- Testing
- Educational video
- Volunteers
- 280 people
- Sponsor
- Sligo General Hospital
Postoperative Complications
Effect of Different Anesthetic Techniques for Isolated Systolic Hypertensive Patients of Abdominal Surgery on Postoperative Hospital Stay and Morbidity
In General anesthesia, two main ways of pain control are used intra-operatively, one is opioids, the other is epidural. Many colleges prefer using epidural analgesia because it is potent and more effective , and also the benefits…
- Trial name
- NCT01884298
- Where
- China
- Sponsor
- Peking University First Hospital
Chest Pain
Pain During Chest Tube Withdrawal: Evaluation Using Pan Monitor
Pain evaluation remains a clinical problem. Pain Monitor allows pain evaluation using the measurement of skin conductance. Withdrawal of chest tube can be painful and the purpose of the study was to compare auto-evaluation of…
- Trial name
- Pain Drain (NCT02015858)
- Testing
- Chest drain withdrawal, Pain Monitor
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Foch
Epidural Anesthesia, Cesarean Section
A Comparison of Different Concentration Ropivacaine for Patient-controlled Epidural Analgesia
To compare the postoperative analgesic effect and the intensity of motor block in different concentration ropivacaine plus fentanyl when used epidurally with a patient-controlled analgesia device after Cesarean delivery.
- Trial name
- PCEA (NCT03195309)
- Testing
- Ropivacaine, Fentanyl
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Analgesia, Epidural
Comparison of Safety and Efficacy Between PIEB and CEI for Labour Epidural Analgesia
The goal of this clinical trial is to compare safety and efficacy of programmed intermittent epidural bolus (PEIB) and continuous epidural infusion (CEI) in parturients during active phase of labour.
- Trial name
- NCT06889285
- Testing
- Continuos epidural infusion, Programmed intermittent epidural bolus
- Where
- Malaysia
- Volunteers
- 76 people
- Sponsor
- Hospital Universiti Sains Malaysia
Postoperative Protein Catabolism
Effect of Intravenous Nutrition and Epidural Analgesia on Protein Loss After Surgery
Loss of muscle mass and body protein are the main causes of fatigue after bowel surgery, which may result in a longer hospital stay and a higher rate of complications.
- Trial name
- NCT00614133
- Testing
- Intravenous nutrition with glucose and amino acids, Intravenous nutrition with glucose and amino acids.
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Liver Surgery
Anterior Quadratus Lumborum Block at the Lateral Supra-arcuate Ligament for Analgesia After Open Liver Surgery
This is a prospective, randomized, controlled, noninferiority trial for evaluating the efficacy of ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament versus thoracic epidural analgesia after…
- Trial name
- NCT04668391
- Testing
- Ultrasound-guided anterior quadratus lumborum block at the lateral supra-arcuate ligament, Thoracic epidural analgesia
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Zhejiang Cancer Hospital
Epidural; Anesthesia
Epidural Space Verification With the CompuFlo®
The purpose of this single arm open-label study is to capture additional data that can add to the original COMPASS (CompuFlo® Assessment Study) clinical trial database that supported the 510(k) application, which was given…
- Trial name
- MC-PMS (NCT03625232)
- Testing
- CompuFlo® Epidural Computer Controlled System
- Where
- 11 sites in Belgium, Chile and 4 more
- Volunteers
- 250 people
- Sponsor
- European e-Learning School in Obstetric Anesthesia
Pancreatic Neoplasms
Analgesia and Pancreatic Cancer Surgery
Long-term survival for patients with pancreatic carcinoma is low, even following resection, the 5-year survival rate of patients ranges from 10 to 25%1.
- Trial name
- NCT01929915
- Testing
- Epidural patient controlled analgesia, Intravenous patient controlled analgesia
- Where
- Taiwan
- Volunteers
- 135 people
- Sponsor
- National Taiwan University Hospital
Cutaneous Fistula, Laryngectomy
Effect of Cervical Epidural Analgesia on the Occurrence of Pharyngocutaneous Fistula
Pharyngocutaneous fistula (PCF) is the most commonly reported postoperative complication in total laryngectomy patients. PCF significantly increases morbidity, length of hospitalization, and cost of care, in addition to delaying…
- Trial name
- NCT02870556
- Testing
- cervical epidural analgesia
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Assiut University
Pregnant Women, Labour Analgesia
A Research Comparing Efficacy of PIEB Plus PCEA vs CEI Plus PCEA for Labour Analgesia
During labour process, one of the most effective ways to manage pain is via epidural analgesia. It is commonly and widely use for all pregnant women underwent labour process.
- Trial name
- NCT07592364
- Testing
- Programmed intermittent epidural bolus 10 ml, continuous epidural infusion
- Where
- Malaysia
- Volunteers
- 88 people
- Sponsor
- Aiman Bin Ab Adzim
Labour Analgesia, Epidural Anaesthesia
Higher vs Lower Lumber Epidural Catheter Insertion During Labour: A Randomised Trial to Compare Efficacy.
This study will randomise pregnant women to labour epidural at a higher versus a lower lumbar level. Outcomes relating to success or failure of the epidural catheter at this level will be assessed.
- Trial name
- NCT06850636
- Testing
- Epidural Analgesia
- Where
- Ireland
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- The Rotunda Hospital
Cesarean Section
The Effect of Warm Local Anesthetic Solution on Epidural Anesthesia
The investigators are going to compare the onset and duration of nerve blockage with the use of pre-warmed (38°C) and room temperature (20°C) local anesthetic solutions (ropivacaine and fentanyl) on epidural anesthesia for…
- Trial name
- NCT03860402
- Testing
- Temperature
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Kidney Disease, End-Stage, Kidney Transplant
Comparison of the Effects of General Anesthesia and Combined Spinal-Epidural Anesthesia on Ferroptosis, Humanin and MOTS-c Levels in Renal Transplantation
Renal transplantation is the most effective renal replacement therapy for patients with end-stage renal disease. Ischemia-reperfusion injury may adversely affect graft function and long-term outcomes.
- Conditions
- Kidney Disease, End-Stage, Kidney Transplant, Kidney, Kidney Disease
- Trial name
- NCT07678073
- Testing
- Sevoflurane General Anesthesia, Bupivacaine and Morphine for Combined Spinal-Epidural Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- University of Gaziantep
Delivery, Obstetric, Labor, Obstetric
Effects of a Lateral Position With Hip Flexion and Femoral Internal Rotation During the Second Stage of Labor in Nulliparous Women Receiving Epidural Analgesia
This randomized clinical study evaluated the effects of a lateral position with hip flexion and femoral internal rotation during the second stage of labor in nulliparous women receiving epidural labor analgesia.
- Trial name
- NCT07745192
- Testing
- Lateral Position With Hip Flexion and Femoral Internal Rotation, Conventional Lateral Position
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Pleural Effusion
Comparison of Thoracoscopic Talc Pleurodesis by Thoracic Epidural or General Anesthesia
Video-assisted thoracoscopic surgery (VATS) talc pleurodesis is often carried out in patients with malignant recurrent pleural effusion to relieve symptoms and prevent recurrence.
- Trial name
- NCT01469728
- Testing
- Non-awake VATS talc pleurodesis, Awake VATS talc pleurodesis
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Epidural Analgesia, Obstetric, Maternal Satisfaction
Impact of Patient Choice for Epidural Potency on Maternal Satisfaction
This clinical trial will compare two different approaches to epidural analgesia during labor to see which approach leads to higher patient satisfaction after delivery.
- Trial name
- NCT07414407
- Testing
- Patient-selected epidural management, Standard epidural management
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University
Anaesthesia, Neurodevelopment
Impact of Perinatal Anaesthesia and Analgesia on Neurocognitive Outcomes in Early Childhood
This study aims to determine the impact of perinatal exposure to anaesthesia and analgesia on neurocognitive outcomes in early childhood by analyzing neurocognitive data already obtained from the local prospective observational…
- Trial name
- PANO (NCT02184780)
- Where
- Singapore
- Volunteers
- 468 people
- Sponsor
- KK Women's and Children's Hospital
Normal Pregnancy
Comparative Affect of a Continuous Epidural Infusion of Clonidine During Labour. Prospective Double Blind Randomized Trial
Addition of clonidine to an epidural mixture of local anaesthetic and morphine improves analgesia and reduces the frequency of motor blockade during epidural analgesia.
- Trial name
- NCT00437996
- Testing
- Clonidine, Levobupivacaine, Sufentanil
- Where
- 2 sites in France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon