Clinical trials: Epidural/Anesthesia
Anesthesia, Local
Epidural Catheter Location by Epidural Pressure Waveform
The aim of this preliminary study was to evaluate the new CompuFlo instrument which allows pulsatile waveform recordings.
- Trial name
- NCT04205773
- Testing
- CompuFlo
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- European e-Learning School in Obstetric Anesthesia
Pain
Evaluation of NoL Index and ANI After Nociceptive Stimulation at Different Infusion Rates of Remifentanil Infusion
Contrary to "immobility" and, to a lesser extent, to the "hypnosis/unconsciousness" component of general anaesthesia, the monitoring of "analgesia" remains largely elusive, evaluated mainly through poorly sensitive and…
- Trial name
- NCT02602379
- Testing
- Tetanic stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Severe Acute Pancreatitis
Effect of Epidural Anesthesia on Pancreatic Perfusion and Clinical Outcome in Patients With Severe Acute Pancreatitis
The aim of the study is to evaluate the safety, the potential beneficial effect of epidural anesthesia on pancreatic perfusion and clinical outcome of patients with severe acute pancreatitis.
- Trial name
- NCT01607996
- Testing
- Epidural anesthesia, Patient controlled intravenous analgesia
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University Hospital, Geneva
Epidural Anesthesia, General Anesthesia
Thoracic Epidural Versus General Anesthesia for Laparoscopic Cholecystectomy
Eighty two patients planned to undergo elective laparoscopic cholecystectomy were divided into two groups, T and G, randomly. In Group T all patients underwent laparoscopic cholecystectomy under thoracic epidural anesthesia with…
- Trial name
- NCT04721054
- Testing
- Thoracic epidural effect on heart rate in Laparoscopic Cholecystectomy (bupivacaine and lignocaine), general anesthesia effect on heart rate in Laparoscopic Cholecystectomy
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Armed Forces Hospital, Pakistan
Anesthesia, Spinal and Epidural, Adverse Effect
Intravenous Bolus of Phenylephrine vs. Norepinephrine in Preventing Hypotension After Spinal Anesthesia
The purpose of the study is to determine if an intravenous bolus of phenylephrine is more effective compared to an intravenous bolus of norepinephrine associated with crystalloid loading for maintaining blood pressure during a…
- Conditions
- Anesthesia, Spinal and Epidural, Adverse Effect, Hypotension, Complications, Cesarean Section
- Trial name
- NorPN (NCT02854787)
- Testing
- Phenylephrine, Norepinephrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Complications; Anesthesia, Spinal and Epidural, in Pregnancy
The Effect of the Timing of Colloid and Crystalloid Infusions on Postspinal Hypotension After Spinal Anesthesia for Caesarian Section
Prevention of postspinal hypotension after spinal anesthesia for caesarian section by use of preoperative or intraoperative volume replacement.
- Trial name
- NCT02680678
- Testing
- Colloid Preload, colloid co-load, Crystalloid preload
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Pediatric Surgical Patients, Preemptive Epidural Analgesia
The Impact of Preemptive Epidural Analgesia on Acute Postoperative Pain in Pediatric Orthopedic Surgery
Management of postoperative pain is critical in the pediatric patients, however, safe and effective analgesia for pediatric surgical patients remains a challenge.
- Trial name
- NCT02813018
- Testing
- 0.2 ml/kg of 0.2% ropivacaine, 0.2mg/kg of Normal Saline
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Epidural Anesthesia in Labor and Delivery
The Effects of Epidural Analgesia on Maternal-Infant Bonding and Birth-Related Trauma
This prospective, single-center study aims to evaluate the effects of epidural analgesia on maternal-infant bonding and perceived birth-related trauma in women undergoing vaginal delivery.
- Trial name
- NCT07077785
- Testing
- Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Adiyaman University Research Hospital
Labor Pain
Doula Combined Latent Phrase Epidural Analgesia in Primiparous Women
Accumulating evidence indicated that neuraxial analgesia in the latent phase of the first stage of labor would be an effective and safe health care procedure for nulliparas.
- Trial name
- DCLEAP (NCT00664118)
- Testing
- Doula combined analgesia, Analgesia without doula
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Spinal and Epidural Anaesthesia-Induced Headache During Pregnancy
Establishment of a Predictive Model for Post-dural Puncture Headache
The goal of this clinical trial is to establish a predictive model for post-dural puncture headache. The main questions it aims to answer are: Changes in intracranial pressure after spinal puncture (or lumbar puncture).
- Trial name
- NCT06800859
- Testing
- Supplement fluids
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Yilin Zhao
Knee Osteoarthritis
Influence of Central Sensitization on Efficacy of Patient-controlled Epidural Analgesia in Osteoarthritis Patients Undergoing Total Knee Replacement
Nociceptor inputs can trigger a prolonged but reversible increase in the excitability and synaptic efficacy of neurons in central nociceptive pathways, the phenomenon of central sensitization.
- Trial name
- NCT01863342
- Testing
- CSI score < 40, CSI score ≥ 40
- Where
- South Korea
- Volunteers
- 98 people
- Sponsor
- Yonsei University
Maternal Anaesthesia and Analgesia Affecting Fetus or Newborn, Breast Feeding
Intrapartum Epidural Fentanyl and Breast-feeding in the Immediate Postpartum Period: a Prospective Cohort Study
Intrapartum epidural analgesia has been associated with adverse breastfeeding outcomes. One potential mechanism involves transfer of epidural fentanyl across the placenta and neonatal blood-brain barrier, where it can…
- Conditions
- Maternal Anaesthesia and Analgesia Affecting Fetus or Newborn, Breast Feeding, Fentanyl, Bupivacaine
- Trial name
- NCT01488149
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Arthroplasty, Replacement, Knee, Nerve Block
Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty
The purpose of this study is to further investigate the efficacy of adductor canal nerve blocks for pain management after total knee replacement.
- Trial name
- NCT02121392
- Testing
- Adductor Canal Nerve Block Catheter, Bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Thoracic Epidural Analgesia, Gastric Cancer
General Anesthesia and General Anesthesia Combined With Thoracic Epidural Anesthesia
This randomized controlled trial investigated whether adding thoracic epidural analgesia to general anesthesia affects intraoperative neuromuscular blockade and opioid requirements in patients undergoing gastric cancer surgery.
- Trial name
- NCT05907811
- Testing
- Neuromuscular blocker usage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Labor Pain
Optimum Length of Catheter in the Epidural Space for Labor Analgesia in Non-obese Women: a Randomised Controlled Trial of 4 cm Versus 5 cm
Epidural analgesia was introduced to the world of obstetrics in 1909 by Walter Stoeckel. Over the following 100 years it has developed to become the gold-standard for delivery of intra-partum analgesia, with between 60 and 75% of…
- Trial name
- NCT04946032
- Testing
- Epidural catheter
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Gastrostomy
Transversus Abdominis Plane Block on Stress Response
This study evaluates the effect of transversus abdominis plane(TAP) block combined with general anesthesia on perioperative stress response in patients undergoing radical gastrectomy.
- Trial name
- NCT03035916
- Testing
- Transversus abdominis plane block, Epidural anesthesia, control
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Jilin University
Labor Pain, Full Term Pregnancy
Patient Controlled Remifentanil Analgesia for Normal Labour
Patient controlled remifentanil analgesia might offer comparative overall patient satisfaction and improved quality of analgesia after normal labour with continuous epidural analgesia.
- Trial name
- NCT04541719
- Testing
- Patient-controlled remifentanil analgesia, Epidural analgesia
- Where
- Egypt
- Sponsor
- Mansoura University
Infectious Complications (Epidural Abscess or Meningitis), Obstetrical Neuraxial Anaesthesia
Primary Immunodeficiencies and Obstetrical Neuraxial Anaesthesia
The purpose of this study is to evaluate if neuraxial anesthesia (epidural or intradural anesthesia) used during childbirth is associated with more frequent infectious complications in patients with primary immunodeficiencies…
- Trial name
- ANEU-DIP (NCT06449066)
- Testing
- Non applicable
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteo Arthritis Knee
Epidural Analgesia vs Adductor Canal Block in Bilateral TKA
This study evaluates postoperative analgesic efficacy within 48 hours between epidural analgesia and single-shot bilateral adductor canal blocks in bilateral total knee arthroplasty.
- Trial name
- NCT03205540
- Testing
- Continuous epidural block, Bilateral single-shot bilateral adductor canal blocks
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Mahidol University
Shivering
Assessment Of Shivering With iSeismograph
Shivering is a common side-effect of epidural anesthesia. In studies to date, the assessment of shivering has been based on a simple scale using descriptive words rather than actual measurements.
- Trial name
- NCT02436174
- Testing
- novel device
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia