Clinical trials: Epidural/Anesthesia
Epidural Anesthesia
Heating Precondition of Epidural Catheter Decrease the Incidence of Injury to Blood Vessel During Epidural Catheter Placement
To explore the effect of heating precondition of epidural catheter on the incidence of injury to blood vessel during epidural catheter placement.
- Trial name
- NCT02537665
- Testing
- heating precondition
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Labor Pain, Analgesia, Epidural
Comparing PIEB and CEI for Labor Pain Relief
The purpose of this randomized controlled trial is to compare the efficacy and safety of two epidural analgesia maintenance methods for labor pain relief: Programmed Intermittent Epidural Bolus (PIEB) and Continuous Epidural…
- Conditions
- Labor Pain, Analgesia, Epidural, Analgesia, Obstetrical, Labor, Obstetric
- Trial name
- COPILOT (NCT07395934)
- Testing
- PIEB + PCEA, CEI + PCEA
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Da Nang Family General Hospital
Medical; Abortion, Fetus
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Termination of Pregnancy Analgesia
This study included women who underwent voluntary second trimester termination of pregnancy. Patients were randomized to programmed intermittent epidural anesthetic bolus or continuous epidural infusion for pain analgesia.
- Trial name
- NCT01860521
- Testing
- Programmed Intermittent Epidural Bolus, Continuous Epidural Infusion, Procedure of interruption of pregnancy
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Malondialdehyde, Heme Oxygenase
The Effects of Two Anesthetic Drugs on Some Enzyme Levels in Patients Undergoing Lower Extremity Surgery
The primary aim of this study was to compare the effects of dexmedetomidine and ketamine, which are administered intravenously during surgery, on the levels of malondialdehyde, an antioxidant, anti-inflammatory enzyme, heme…
- Conditions
- Malondialdehyde, Heme Oxygenase, C-Reactive Protein
- Trial name
- NCT05950555
- Testing
- Saline, Dexmedetomidine, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
Epidural Anesthesia, Spinal Ultrasound
Ultrasound Versus Palpation for Epidural Catheterization
The study will assess the benefit of using spinal ultrasound before epidural catheter insertion compared to the conventional palpation technique in women undergoing cesarean section.
- Trial name
- NCT02410226
- Testing
- Double-space combined spinal-epidural anesthesia, Preprocedure spinal ultrasound
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Postoperative Pain, Pediatric Anesthesia Department
Pediatric Postoperative Pain Management
This prospective, observational study evaluates the effectiveness of perioperative pain management strategies in pediatric patients undergoing elective surgical procedures.
- Conditions
- Postoperative Pain, Pediatric Anesthesia Department, Regional Anaesthesia, Pain Scale
- Trial name
- NCT07392827
- Where
- Turkey (Türkiye)
- Volunteers
- 219 people
- Sponsor
- Hacettepe University
Anesthesia
The Analgesic Effect of Quadratus Lumborum Block and Its Postoperative Implication on Kidney Function
Regional anesthesia is frequently used in major surgery in association with general anesthesia to ensure adequate postoperative patient analgesia and to decrease the intra- and postoperative use of systemic analgesic drugs.
- Trial name
- NCT04425174
- Testing
- Quadratous lumborum block, Epidural anesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Traumatic Rib Fracture
Thoracic Blocks Versus Thoracic Epidural and Patient Controlled Anesthesia in Traumatic Rib Fracture Patients
The primary objective of this study is to investigate whether continuous PVB is equal in efficacy to epidural anesthesia in terms of analgesia in patients with INR lower than 1.2, or is continuous ICNB equal in efficacy to PCA in…
- Trial name
- NCT01599403
- Testing
- Paravertebral Block, Intercostal Nerve Block, Epidural Block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Knee Osteoarthritis
Ultrasound Guided Femoral Nerve Block Catheter Analgesia Compared With Epidural Analgesia for Patients With Knee OA (Osteoarthritis) Who Underwent Unilateral Total Knee Replacement
Post-operative pain following total knee replacement can be disabling and sometimes lead to the need for prolonged hospital stay.
- Trial name
- NCT01586429
- Testing
- Ultrasound guided femoral nerve block catheter analgesia compared with epidural analgesia for patients with knee OA (osteoarthritis)
- Where
- 2 sites in Saudi Arabia
- Sponsor
- King Saud University
Lumbosacral Radicular Pain
Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
This is a research study of SP-102, an experimental medication designed to relieve pain in patients with a specific type of leg pain.
- Trial name
- NCT03372161
- Testing
- SP-102
- Where
- 37 sites in United States
- Volunteers
- 401 people
- Sponsor
- Scilex Pharmaceuticals, Inc.
Anxiety, Pain
Music Use in Parturients Admitted to Labor & Delivery
The goal of this clinical trial is to learn if music use affects anxiety or pain levels in parturients admitted to labor and delivery. It will also learn about the effect of music use on patient satisfaction.
- Conditions
- Anxiety, Pain, Patient Satisfaction
- Trial name
- NCT06969105
- Testing
- Music
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Gastric Cancer
Propofol EC50 for Inducing Loss of Consciousness in General Combined Epidural Anesthesia
The beneficial of perioperative usage of thoracic epidural anesthesia and analgesia in various thoracic and upper abdominal surgery are well studied.
- Trial name
- NCT05124704
- Testing
- 5-8ml 0.375% ropivacaine, 5-8ml normal saline
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wang Jiangling
General Anesthesia, Inhalation; Gas
End Tidal Anesthetic Concentration in Different Anesthesia Techniques Where Depth of Anesthesia Adjusted With Entropy
The aim of this study is to adjust the end tidal inhalation anesthetic concentration by observing the entropy value in patients who will be provided anesthesia maintenance with volatile anesthetics after applying the routine…
- Trial name
- NCT04203290
- Testing
- Bupivacaine, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University
Pregnancy
Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base
This is a data base building project on the use of pre-procedure ultrasound for the performance of labor epidural pain relief and spinal anesthesia for cesarean deliveries.
- Trial name
- NCT01192074
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Combined Spinal-epidural Anesthesia
The ED50 of DEX for Providing Sedation in Different Female Age Group
Dexmedetomidine(DEX) could provide dose-dependent sedation , analgesia , anti-anxiety and inhibition of sympathetic nerves and other effects.
- Trial name
- NCT02773017
- Testing
- Dexmedetomidine A, Dexmedetomidine B, Dexmedetomidine C
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Pain Monitor During Anesthesia
Observational Evaluation of the Last Version of the PMD200TM
Title: Evaluation of the last version of the PMD200TM and its NoL index in patients undergoing laparotomies with intraoperative epidural analgesia Objectives: Measure NoL Index changes after a standardized nociceptive electrical…
- Trial name
- NCT02884778
- Testing
- Detection of pain after nociceptive stimulus
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Post Operative Pain
Pain Management After Total Knee Replacement
Aim of this study is to compare post-operative analgesic efficacy of continuous epidural analgesia versus ultrasound guided continuous femoral nerve block and adductor nerve block after unilateral total knee replacement using…
- Trial name
- NCT05249478
- Testing
- bupivacaine and fentanyl
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Severe Acute Pancreatitis
Epidural Analgesia for Pancreatitis (Epipan Study)
Acute pancreatitis (AP) is a common disease whose incidence in the US reaches 35 per 100,000 population annually. Its main causes in adults are gallstone migration into the common bile duct and alcohol abuse.
- Trial name
- EPIPAN (NCT02126332)
- Testing
- ropivacaine and sufentanil, acetaminophen, nefopam, tramadol, opidoids
- Where
- France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anesthesia, Recovery Period
TAPB vs. Caudal for Lower Abdominal Surgery in Children: A Double-Blinded Randomized Controlled Trial
Transversus abdominis plane block (TAPB) has emerged as a safe and effective regional anesthesia technique for providing postoperative lower abdominal analgesia.
- Trial name
- NCT02160821
- Testing
- Caudal Epidural, Transversus Abdominis Plane Block
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Nemours Children's Clinic
Cervical Incompetence
Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC)
The investigator aimed to compare the effect of anesthesia on overall postoperative outcomes including post-operative pain score and the fetal well-being (heart rate) in patients undergoing transabdominal cervico isthmic…
- Trial name
- NCT03636048
- Testing
- Bupivacaine Hcl 0.5% Inj, Propofol 10 milligram/ML
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital