Clinical trials: Epidural/Anesthesia
Pain
Sole Local Anesthetic Versus Opioid Plus Local Anesthesia in Epidural Labor Analgesia
It is common for obstetric anesthesia using opioid supplement to local anesthetics for epidural labor pain control. Given the low doses of these epidural drugs, we never doubt the necessity of the supplement of opioid to lacal…
- Trial name
- OLAA (NCT02036242)
- Testing
- Sole local anesthetic, Sufentanil (Opioid plus local anesthetic), Ropivacaine
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Labor Pain
The Effect of Metrics Based Performance Based Progression in Provision of Labor Epidural Analgesia
Procedural skills are an important determinant of clinical outcomes for certain patient groups. Training for procedural skills in the medical profession is still largely based on an apprenticeship model.
- Trial name
- NCT02185079
- Testing
- Training to proficiency, Conventional training
- Where
- Ireland
- Volunteers
- 16 people
- Sponsor
- Cork University Hospital
Childbirth, Epidural; Anesthesia
Evaluation of the Impact of Ambulatory Epidural on Maternal Satisfaction During Delivery and Postpartum
Childbirth is a special event for women. Maternal satisfaction regarding childbirth is quite important, that is why this factor has to be taken into account.
- Trial name
- PERIDEAMBU (NCT06550570)
- Testing
- QEVA questionnaire
- Where
- 2 sites in France
- Volunteers
- 126 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Pain, Renal Cancer
Comparison Between Epidural Analgesia and Intrathecal Opioid Analgesia for Pain Management in Open Nephrectomy
Nephrectomy is a surgical procedure of choice for patients suffering from renal cell carcinoma (RCC). Even though the laparoscopic approach is considered to cause fewer complications and reduce hospital stay, open surgery is…
- Conditions
- Pain, Renal Cancer, Surgical Procedure, Unspecified
- Trial name
- NCT06595329
- Testing
- Epidural analgesia, Intrathecal opioid analgesia
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- University Hospital of Split
Labor Pain, Delivery Complication
Effect of Epidural Analgesia on Labour, Neonatal and Maternal Outcomes.
Lumbar epidural analgesia is the most used method for reducing labour pain, but its impact on the duration of the second stage of labour and on neonatal and maternal outcomes remains debated.
- Conditions
- Labor Pain, Delivery Complication, Regional Anesthesia Morbidity
- Trial name
- NCT05579808
- Testing
- Epidural Analgesia
- Where
- Italy
- Volunteers
- 21,808 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Anesthesia, Obstetrical, Analgesia, Epidural
Epidural Analgesia During Labour
Randomized single blind trial based on comparing the way the local anesthetic is dosificated during labour. The pain control is evaluated and compared with both dosage techniques (PCEA vs PIEB)using levobupivacaine and fentanyl.
- Trial name
- PIEBvsPCEA (NCT03133091)
- Testing
- PIEB: Patient Intermittent Epidural Boluses, PCEA: Patient Controlled Epidural Analgesia
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital del Rio Hortega
Cesarean Section
Fluid Volume-hypotension Association in Cesarean Under Neuraxial Anesthesia
Hypotension resulted from neuraxial block is a common problem, of which is a special issue in patients undergoing Cesarean section.
- Trial name
- VOHOCUNA (NCT01013090)
- Testing
- Ringer's Lactate, Six percent hydroxyethyl starch
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanjing Medical University
Vaginal Delivery
The Effects of Combined Spinal Epidurals on Fever During Labor of First-Time Mothers
The purpose of this study is to determine if the epidural of local anesthetics has an effect on fever that may occur in first time mothers during labor.
- Trial name
- CSE (NCT00802646)
- Testing
- saline, fentanyl/bupivacaine/epinephrine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Anesthesia, Spinal, Anesthesia, Epidural
Alcohol 70% Versus Chlorhexidine 0.5% in the Spinal Anesthesia Skin Antissepsis
Context: The neuraxial blocks, spinal anesthesia and epidural anesthesia are among the most frequently performed procedures worldwide, and despite the advancements of medical equipment, remain dependent on experience and practice…
- Conditions
- Anesthesia, Spinal, Anesthesia, Epidural, Antisepsis
- Trial name
- NCT02833376
- Testing
- alcohol antisepsis, chlorhexidine antisepsis
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Universidade do Vale do Sapucai
Labor Active Dilated Cm
Analgesia in Labor, a Prospective Parallel Study to Compare Regional Analgesia and Intravenous (IV) Pethidine Analgesia
To compare combined spinal epidural, epidural and IV pethidine analgesia and their effects on the mother, fetus, newborn and the course of labor.
- Trial name
- NCT01290289
- Testing
- Epidura, CSE & IV
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Hypotension, Anesthesia; Adverse Effect, Spinal and Epidural
ONDANSETRON AND EFFECTIVE DOSE IN 50% OF SUBJECTS OF PROPHYLACTIC NOREPINEPHRINE INFUSIONS FOR PREVENTING SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING CESAREAN DELIVERY
Spinal anesthesia is the preferred technique for elective cesarean section as per ASA guidelines. Hypotension is the main complication of this technique and is secondary to both sympatholysis and its associated decrease in…
- Conditions
- Hypotension, Anesthesia; Adverse Effect, Spinal and Epidural, Cesarean Section
- Trial name
- NCT04703088
- Testing
- Ondansetron 4 MG, 0.9% Saline
- Volunteers
- 60 people
- Sponsor
- Laval University
Postoperative Analgesia
Analgesic Effect of Ropivacaine Combined With Hydromorphone for CSEA After Total Knee Arthroplasty
The aim of this study is to investigate the continuous analgesic effect and side effects of ropivacaine combined with hydromorphone for combined spinal-epidural anesthesia(CSEA) after total knee arthroplasty and to explore its…
- Trial name
- NCT06205199
- Testing
- Hydromorphone was injected into the subarachnoid space
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Second Hospital of Jilin University
Epidural Analgesia, Obstetric
Impact of Low-Dose Epidural Analgesia on Labour Progression in Low-Risk Women
Aim of the study was to analyse data on cervical dilation and fetal descent patterns in low-risk women, who did or did not receive intermittent low-dose epidural analgesia (EA), and who had either a vaginal or a caesarean…
- Trial name
- NCT06987591
- Where
- Italy
- Volunteers
- 5,995 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Epidural Analgesia, Analgesic Effect
Epidural Analgesia and Maternal Fever During Labor
Women who receive epidural analgesia during labor are more likely to develop fever than those who do not. Maternal fever during labor can produce various harmful effects on both mothers and infants.
- Conditions
- Epidural Analgesia, Analgesic Effect, Fever
- Trial name
- NCT04940091
- Testing
- Epidural analgesia
- Where
- 8 sites in China
- Volunteers
- 1,051 people
- Sponsor
- Peking University First Hospital
Analgesia
Ultrasound Guided : Retrolaminar Block Versus Thoracic Epidural Analgesia Following Laparoscopic Cholecystectomy
The aim of this study is to evaluate analgesic effect of ultrasound-guided retrolaminar block vs ultrasound-guided thoracic epidural analgesia in pain control following laparoscopic cholecystectomy.
- Trial name
- NCT04835415
- Testing
- Bilateral retrolaminar block, Thoracic epidural analgesia
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Surgical Procedure, Unspecified
Thoracic Epidural Versus General Anaesthesia in Cholecystectomy
CONTEXT AND AIMS: The aim of the study is to compare patients satisfaction of thoracic epidural and general anesthesia procedures in patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- EVGAC (NCT03107832)
- Testing
- thoracic epidural anesthesia procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Abant Izzet Baysal University
Respiration Disorders
Epidural Analgesia and Postoperative Respiratory Functions (EPAPRES)
Patients operated with posterolateral thoracotomy were enrolled. Post-operative analgesia was provided either by TEA with 0.1% bupivacaine or pethidine based intravenous analgesia (IVA) in our sample population.
- Trial name
- EPAPRES (NCT03643757)
- Testing
- Thoracic epidural analgesia, Bupivacaine
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yedikule Training and Research Hospital
Phantom Limb Pain, Pain, Chronic
Continuous Sciatic Nerve Block vs Epidural Analgesia in Lower Limb Amputation for Postoperative Pain
Controlled clinical trial of two parallel groups, with random assignment 1:1, non-inferiority, blinded for the patient, for who administers the intervention and for who analyzes the data. 112 participants
- Trial name
- Ampupain (NCT05608733)
- Testing
- Epidural catheter, Continuous sciatic nerve block
- Where
- Colombia
- Volunteers
- 112 people
- Sponsor
- Universidad de Antioquia
Pregnancy
Comparison of Echo-assisted ALR Technique and Traditional ALR Technique for the Placement of an Epidural Catheter in the Obstetric Patient
This is a randomized, open-label, single-center clinical trial. The purpose of the study is to understand whether the aid of ultrasound assessment is useful in improving the competence of resident.
- Trial name
- OST-22-01 (NCT06811649)
- Testing
- Ultrasound guided injection with local anaestethic
- Where
- Italy
- Volunteers
- 146 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Eventration, Regional Anesthesia
Serratus Intercostal Block Versus Epidural/Port Infiltration Analgesia in Eventration: Prospective Non Inferiority Study
Adequate pain control, rehabilitation and early postoperative recovery are currently the model to follow according to the recommended guidelines.In this project the main objective is to evaluate 2 different analgesic strategies…
- Conditions
- Eventration, Regional Anesthesia, Epidural; Anesthesia, Abdominal Hernia
- Trial name
- Analgesic Stra (NCT06014749)
- Testing
- undergo, ultrasound, Local anesthetic
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Hospital del Rio Hortega