Clinical trials: Epidural Analgesia, Obstetric
Obstetric Labor Complications
Quick Epidural Top-up With Alkalinized Lidocaine for Emergent Caesarean Delivery
Prospective randomized study comparing the use of lidocaine 2% with epinephrine buffered with sodium bicarbonate and lidocaine 2% with epinephrine as epidural top-up for extremely urgent cesarean section during labour.
- Trial name
- QETAL (NCT05313256)
- Testing
- Lidocaine epinephrine buffered with sodium bicarbonate, Lidocaine epinephrine
- Where
- 2 sites in France
- Volunteers
- 65 people
- Sponsor
- University Hospital, Bordeaux
Epidural Analgesia, Obstetric
Impact of Low-Dose Epidural Analgesia on Labour Progression in Low-Risk Women
Aim of the study was to analyse data on cervical dilation and fetal descent patterns in low-risk women, who did or did not receive intermittent low-dose epidural analgesia (EA), and who had either a vaginal or a caesarean…
- Trial name
- NCT06987591
- Where
- Italy
- Volunteers
- 5,995 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Labor Pain, Obstetric Pain
Association Between Bolus Rate and the Adequacy of Labor Analgesia Using Timed-intermittent Boluses
Administration of anesthetic solution into the epidural space is usually accomplished by a combination of continuous infusion, provider-administered boluses and patient-administered boluses (patient controlled epidural analgesia…
- Trial name
- NCT02340806
- Testing
- CADD-Solis pump (Smiths Medical)
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pregnancy, Epidural Analgesia, Obstetric
Intelligence and Neurodevelopmental Outcome After Prenatal Exposure to Labour Epidural Analgesia: a Sibling Matched Clinical Ambidirectional Cohort Study
In Belgium, labour epidural analgesia (LEA) has been used for decades in the vast majority of vaginal deliveries (up to 83% of deliveries).
- Trial name
- NCT07014956
- Testing
- Labour epidural analgesia
- Where
- Belgium
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Epidural Analgesia, Medical Education
Simulation-Based Training for Epidural Analgesia Placement
Epidural analgesia is the gold standard for labor pain management, widely recommended by the WHO and included in Italy's essential levels of care (LEA) since 2017.
- Conditions
- Epidural Analgesia, Medical Education, Obstetric Anesthesia
- Trial name
- NCT07056140
- Testing
- Epidural Simulation Training, Standard Clinical Training
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Padova
Hypotension, Labor Complication
Leg Elevation to Prevent Hypotension During Labor
When hypotension is related to epidural placement, this can occur within 15-60 minutes after placement. The purpose of this study is to build upon this preliminary work and to use a randomized controlled trial to examine the…
- Trial name
- NCT05674838
- Testing
- Leg Elevation
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Labor, Obstetric, Epidural Analgesia, Obstetric
Integrated Intrapartum Supportive Care and Pushing Strategies in Women Receiving Low-Dose Epidural Analgesia
This prospective, three-arm, non-randomized quasi-experimental study aims to evaluate integrated intrapartum supportive care combined with different pushing strategies among women at 37-42 weeks of gestation who receive low-dose…
- Conditions
- Labor, Obstetric, Epidural Analgesia, Obstetric, Labor Duration
- Trial name
- NCT07663500
- Testing
- Integrated Care with Immediate Pushing, Integrated Care with Spontaneous Pushing Group, Standard Routine Care
- Where
- Taiwan
- Volunteers
- 159 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Pregnancy, Breech Presentation
The Effect of Combined Spinal-Epidural Analgesia on the Success of External Cephalic Version (ECV) for Breech Position
We aim to answer the clinical question: Does combined spinal-epidural analgesia improve the success rate of external cephalic version? We hypothesize that neuraxial analgesia (spinal or epidural analgesia) during version for…
- Trial name
- Version (NCT00565383)
- Testing
- Combined spinal-epidural analgesia, Intravenous fentanyl (50mcg)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Northwestern University
Labor Pain
Intermittent Automated Devices for Labor Analgesia in Emilia Romagna
The study aims to determine whether the use of automated intermittent devices for labor analgesia could prevent the increase of instrumental deliveries, with same analgesia.
- Trial name
- PA-RER (NCT02710877)
- Testing
- Programmed Intermittent bolus, Manual epidural bolus, Levobupivacaine
- Where
- 3 sites in Italy
- Volunteers
- 671 people
- Sponsor
- University of Modena and Reggio Emilia
Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Multimodal Approach to the Intrathecal Catheter for Obstetric Accidental Dural Puncture
Accidental dural puncture is an uncommon complication of epidural analgesia and can cause postdural puncture headache.
- Trial name
- NCT05910086
- Testing
- collection of data from the medical record
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Labor Pain and to Reduce Pain
Does the Volume of Medication Affect the Success of Labor Epidural Analgesia
The purpose of this study is to evaluate whether changing the volume and concentration of a medication affects the quality of pain relief and the side effects associated with labor epidural analgesia.
- Trial name
- EpiVol (NCT07684365)
- Testing
- administration of bupivacaine 7.5 mg and fentanyl 24 mcg every 40 minutes
- Volunteers
- 70 people
- Sponsor
- Beth Israel Deaconess Medical Center