Clinical trials: Epidural Analgesia, Obstetric
Postdural Puncture Headache, Epidural Analgesia, Obstetric
A Prospective Cohort Study to Evaluate the Safety, Efficacy, and Usability of the EpiZact Device
The purpose of the study is to learn more about a new device, the EpiZact Epidural Device, that may be helpful for reducing the likelihood of wet tap when a labor epidural is placed.
- Trial name
- NCT06729255
- Testing
- EpiZact-assisted epidural placement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Postpartum Hemorrhage
Retrospective Evaluation of the Impact of Epidural on the Risk of Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is a major complication of childbirth. Epidurals are often implicated in the onset of postpartum hemorrhages.
- Trial name
- NCT06816654
- Testing
- Data extraction from medical records
- Where
- Belgium
- Volunteers
- 5,753 people
- Sponsor
- Tatiana Besse-Hammer
Labor Pain, Nociceptive Pain
Nociception Level Index (NOL Index) for Obstetrical Pain Assessment Under Epidural Analgesia.
Pain has been defined by the International Association for the Study of Pain (IASP) as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage".
- Conditions
- Labor Pain, Nociceptive Pain, Epidural Analgesia, NOL Index
- Trial name
- NCT05898737
- Testing
- NOL-Index
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Labor Pain, Epidural Analgesia for Labour and Delivery
Early Labor Pre-Marking for Epidural Analgesia: Ultrasound vs Manual Palpation
The goal of this clinical trial is to learn if finding and marking the best spot on the back early in labor helps doctors perform epidural pain relief more successfully in pregnant women.
- Conditions
- Labor Pain, Epidural Analgesia for Labour and Delivery, Neuraxial Ultrasound
- Trial name
- NCT07669441
- Testing
- Preprocedural Spinal Ultrasound, Conventional Landmark Palpation
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Anesthesia, Obstetric
Dural Puncture Epidural Technique During Cesarean Section
DPE technique was performed by creating a perforation in the dura mater using a pencil point spinal needle (25-27G) through the shaft of an epidural needle.
- Trial name
- NCT06184425
- Testing
- Dural Puncture Epidural technique using pencil-point 25G Whitacre needle, Dural Puncture Epidural technique using pencil-point 27G Whitacre needle
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Obstetric Pain
Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
During labor there is an increased production of inflammatory mediators called cytokines. Higher concentration of certain cytokines has been linked to adverse neonatal and maternal outcomes.
- Trial name
- NCT00361712
- Testing
- Preemptive epidural analgesia, Standard of care
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Postpartum Recovery, Mother-infant Bonding
Labor Epidural Analgesia and Mother-Infant Bonding After Vaginal Delivery
This prospective observational cohort study aims to evaluate the association between postpartum recovery quality and mother-infant bonding in women undergoing vaginal delivery.
- Conditions
- Postpartum Recovery, Mother-infant Bonding, Labor Pain
- Trial name
- NCT07582289
- Testing
- Labor Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ataturk University
Blood Patch, Post-Dural Puncture Headache
Factors Associated With the Onset of Chronic Headaches in Patients Who Received a Blood Patch in Post Partum
The purpose of this study is to identify possible links between conditions for carrying out a blood patch (BP) to treat accidental post dural puncture acute headache (PDPH) in the early post partum period and occurrence of…
- Trial name
- CHROBLOOD (NCT05888324)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Labor Pain, Obstetric Pain
Programmed Intermittent Epidural Bolus (PIEB) Techniques for Labour Analgesia
Epidural Analgesia remains the most effective form of pain relief in labour. After initiating epidural analgesia, there are many epidural drug regimens that can be employed to maintain analgesia for the duration of labour using…
- Conditions
- Labor Pain, Obstetric Pain, Analgesia
- Trial name
- PIEB (NCT06266767)
- Testing
- Levobupivacaine and Fentanyl
- Where
- Qatar
- Volunteers
- 136 people
- Sponsor
- Hamad Medical Corporation
Pregnancy, Breech Presentation
The Effect of Combined Spinal-Epidural Analgesia on the Success of External Cephalic Version (ECV) for Breech Position
We aim to answer the clinical question: Does combined spinal-epidural analgesia improve the success rate of external cephalic version? We hypothesize that neuraxial analgesia (spinal or epidural analgesia) during version for…
- Trial name
- Version (NCT00565383)
- Testing
- Combined spinal-epidural analgesia, Intravenous fentanyl (50mcg)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Northwestern University
Pregnancy, Epidural Analgesia, Obstetric
Intelligence and Neurodevelopmental Outcome After Prenatal Exposure to Labour Epidural Analgesia: a Sibling Matched Clinical Ambidirectional Cohort Study
In Belgium, labour epidural analgesia (LEA) has been used for decades in the vast majority of vaginal deliveries (up to 83% of deliveries).
- Trial name
- NCT07014956
- Testing
- Labour epidural analgesia
- Where
- Belgium
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Low Back Pain, Mechanical
Impact of Epidural Anesthesia on Low Back Function
Back pain is a common complication after the use of epidural anesthesia in obstetric and non-obstetric surgeries and occurs in 30-45% of cases (Brown, 2005).
- Trial name
- NCT04759963
- Where
- 2 sites in Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- South Valley University
Labor, Obstetric, Pain
Estimation of Pain During Epidural Analgesia During Labor
Epidural regional anesthesia is a technique to eliminate or lessen pain during obstetric labor and childbirth. It consists in establishing a catheter into the epidural space and to block the transmission of pain sensations by…
- Trial name
- PERIDANS (NCT02551354)
- Testing
- Portable video pupillometer
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Labour Pain
Spoken Animation for Labour Epidural
The purpose of this study is to evaluate a new animated information film as a tool for introducing the concept of epidural as a method of labour pain relief to expectant women.
- Trial name
- SALE (NCT07202221)
- Testing
- Participant views Epidural animation before reading gold standard written information, Participant receives current gold standard written information alone
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Epidural, Labor Pain
Improving Labour Induction Analgesia: Epidural Fentanyl Bolus at Epidural Initiation for Induction of Labour
Labour pain can be intensified for labour inductions and women undergoing inductions often have earlier and more frequent requests for analgesia.
- Conditions
- Epidural, Labor Pain, Induction of Labor Affected Fetus / Newborn, Obstetric Anesthesia Problems
- Trial name
- NCT04011098
- Testing
- Epidural Fentanyl Bolus, Standard Epidural Group
- Where
- Canada
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Post-Dural Puncture Headache
The Influence of Needle Diameter on Post Dural Puncture Headache
The purpose of this study is to determine whether injection needle pen point type 'PP Gauge 25' should be recommended as a primary choice of needle (in stead of 'PP Gauge 27') for healthy pregnant women who at delivery (vaginal…
- Trial name
- NCT02827058
- Testing
- G25 pencil point needle, G27 pencil point needle
- Where
- 3 sites in Norway
- Volunteers
- 65 people
- Sponsor
- Helse Nord-Trøndelag HF
Labour Analgesia, Epidural Anaesthesia, Duration of Labour
Impact of Timing of Neuraxial Analgesia on Obstetric, Anesthesiologic and Neonatal Outcomes in Induced Labour
The aim of this observational study is to assess the effect of early labour analgesia on obstetric and neonatal outcomes in induced labour in primiparous women with a full-term pregnancy whose labour was induced with a Cook…
- Conditions
- Labour Analgesia, Epidural Anaesthesia, Duration of Labour, Labor, Induced
- Trial name
- TAIL (NCT06886555)
- Testing
- Epidural analgesia for labour pain
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Epidural Analgesia, Hospital Follow-up
Obstetrical Analgesia in the Estaing Hospital Maternity. A Prospective Database to Study the Determinants of Labor Pain and the Resulting Maternal Non Satisfaction.
There is a trend to offer personalized care in many medical domains. In the field of labor pain, it appears that maternal satisfaction about care is multifactorial, and that labor pain is only one of its determinants, competing…
- Trial name
- AOMHE (NCT03314571)
- Testing
- analgesia for labor
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Clermont-Ferrand
Labor Pain
The Effect of a Culturally Sensitive Educational Intervention on Acceptance of Neuraxial Anesthesia
The purpose of this study is to see if an educational intervention provided to pregnant women in early labor has an effect on their decision to use epidural anesthesia for relief of labor pain.
- Trial name
- NCT02672397
- Testing
- Additional Epidural Education
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
Labor Pain
A Novel Approach to Optimize Programmed Intermittent Epidural Bolus (PIEB) Delivery for Labour Analgesia
Programmed intermittent epidural bolus (PIEB) for labour analgesia allows an epidural pump to be programmed to deliver small amounts of the local anesthetic and opioid solution at regularly timed intervals.
- Trial name
- NCT03871530
- Testing
- Coordinate A, Coordinate B, Coordinate C
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- IWK Health Centre