Clinical trials: Epidural Block
Pregnancy
Aseptic Techniques During Epidural Analgesia in the Labor Floor
There is an increasing trend in the incidence of infection related to epidural anesthesia. This could be related to methods of aseptic technique as adopted by the anesthesiologist during the performance of the procedure.
- Trial name
- EAS (NCT01235858)
- Testing
- wearing of sterile gowns, No gown
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pancreatic Cancer, Surgery
Perioperative Epidural Block and Dexamethasone in Pancreatic Cancer Surgery
Pancreatic cancer remains a devastating disease with an average 5-year survival rate of about 3-5%. Previous retrospective studies showed that perioperative epidural block and/or dexamethasone are associated with improved outcome…
- Conditions
- Pancreatic Cancer, Surgery, Epidural Block, Dexamethasone
- Trial name
- NCT04025840
- Testing
- Epidural block, Dexamethasone
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Peking University First Hospital
Pain, Thoracotomy
Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After Thoracotomy
Objective: Epidural analgesia is the gold standard for post-thoracotomy pain relief but is contraindicated in certain patients. An alternative is continuous wound catheter analgesia.
- Trial name
- NCT01698203
- Testing
- ropivacaine 0.75% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun), ropivacaine 0.2% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun)
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Strasbourg, France
Epidural Anesthesia, Spinal Ultrasound
Ultrasound Versus Palpation for Epidural Catheterization
The study will assess the benefit of using spinal ultrasound before epidural catheter insertion compared to the conventional palpation technique in women undergoing cesarean section.
- Trial name
- NCT02410226
- Testing
- Double-space combined spinal-epidural anesthesia, Preprocedure spinal ultrasound
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
Pain, Postoperative
The Effect of Gabapentin on Thoracic Epidural Analgesia Following Thoracotomy
The purpose of this trial is to investigate the effect of gabapentin on thoracic epidural analgesia following thoracotomy, including assessment of both analgesia, pain intensity, pain quality and whether or not gabapentin…
- Trial name
- GABATEA (NCT01116583)
- Testing
- Gabapentin
- Where
- Denmark
- Volunteers
- 104 people
- Sponsor
- University of Aarhus
Prostatectomy, Transversus Abdominis Plane Blockade
Ultrasound-assisted Bilateral Transversus Abdominis Plane Block for Open Prostatectomy
The purpose of this study is to compare the quality of a transversus abdominis plane blockade with an intravenous pain therapy with opioids.
- Conditions
- Prostatectomy, Transversus Abdominis Plane Blockade, Pain
- Trial name
- TAPPro (NCT01625572)
- Testing
- Transversus abdominis plane blockade, Morphine-patient-controlled-analgesia-device
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- Charite University, Berlin, Germany
Pregnant Women>37SA
EpiConCES - Epidural Lidocaine for Conversion to CaEsarean Section
The need to resort to a midwifery course work in cesarean is a common practice. Epidural analgesia for labor analgesia is practiced in 90% of women in obstetric work, as when the cesarean decision is taken course work in practice…
- Trial name
- EpiConCES (NCT02895022)
- Testing
- Lidocaine 2% adrénalinée, Epidural catheter, Caesarean section
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Postoperative Pain
NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy Pain
The investigators investigated whether a strictly controlled pain management with patients participating in a clinical study can attenuate persistence of post-thoracotomy pain.
- Trial name
- NCT01541137
- Testing
- Diclofenac, parecoxib/ valdecoxib, patient controlled epidural analgesia
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Anesthesia
Epidural Anesthesia With Chloroprocaine Versus Lidocaine
Chinese made chloroprocaine has a rapid onset time, effective methodology, can last for a short time, provides fast motor recovery and causes no significant side effects.
- Trial name
- NCT02287870
- Testing
- Chloroprocaine, Lidocaine
- Volunteers
- 120 people
- Sponsor
- Jinling Hospital, China
Urodynamics, Acute Urinary Retention
Effects of Thoracic Epidural Anesthesia on Lower Urinary Tract Function
Acute urinary retention is one of the most common complications after surgery and anesthesia. Overfilling the bladder can stretch and damage the detrusor muscle, leading to atony of the bladder.
- Trial name
- NCT00790231
- Testing
- urodynamic procedure
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain Management Strategies in Liver Resection Surgery
TEA vs. PVB vs. PCA in Liver Resection Surgery
This study aims to compare the efficacy and safety of three alternative methods of analgesia in patients undergoing complex liver resection surgery: 1) thoracic epidural analgesia (TEA), 2) continuous paravertebral block (PVB)…
- Trial name
- NCT02192879
- Testing
- thoracic epidural, continuous paravertebral catheter, Patient-Controlled Analgesia
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Failed Back Surgery Syndrome
EuroPainClinicsStudy IX
Prospective comparison between epiduroscopy procedure, Racz catheter procedure and caudal epidural block in patients with FBSS
- Trial name
- EPCS IX (NCT04686903)
- Testing
- Epiduroscopy treatment, Racz catheter epidural procedure, Caudal epidural block
- Where
- Slovakia
- Volunteers
- 150 people
- Sponsor
- EPC Education s.r.o.
Thoracic Epidural Anesthesia
CompuFlo Thoracic Epidural Study
Traditionally, loss-of-resistance (LOR) to air or saline with a special ground-glass syringe is the technique used to identify epidural space, but failure rates up to 30% have been reported using this technique for thoracic…
- Trial name
- NCT03826186
- Testing
- Traditional (loss-of-resistance technique) thoracic epidural placement, CompuFlo thoracic epidural placement
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- YATISH SIDDAPURA RANGANATH
Pregnancy
Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base
This is a data base building project on the use of pre-procedure ultrasound for the performance of labor epidural pain relief and spinal anesthesia for cesarean deliveries.
- Trial name
- NCT01192074
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Postoperative Pain, Pediatric Surgery
Caudal Epidural Vs. TAP Block for Postoperative Analgesia in Pediatric Infraumbilical Surgery: a RCT
This randomized controlled trial investigates the postoperative analgesic efficacy of caudal epidural block versus ultrasound-guided transversus abdominis plane (TAP) block in pediatric patients undergoing infraumbilical surgery.
- Conditions
- Postoperative Pain, Pediatric Surgery, Anesthesia, Local, Regional Anesthesia
- Trial name
- NCT06895382
- Testing
- Caudal Epidural Block, Transversus Abdominis Plane (TAP) Block, Bupivacaine 0.25%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Namik Kemal University
Analgesia, Epidural
Levobupivacaine for Epidural Analgesia in Labour
In a prospective randomised study involving primiparous women in spontaneous uncomplicated labour with cervical dilatation > 7 cm, epidural analgesia will be given with an initial volume of 20 mL anaesthetic solution, followed by…
- Trial name
- NCT00929682
- Testing
- Randomization between two referenced treatments
- Volunteers
- 136 people
- Sponsor
- University Hospital, Clermont-Ferrand
Prostatectomy
Radical Laparoscopic Prostatectomy. Enhanced Recovery After Surgery (ERAS) Program
Current trends are based on the implementation of enhanced recovery programs (ERP) for most surgical procedures. The transversus abdominis plane (TAP) block has been demonstrated as an effective analgesic alternative in abdominal…
- Trial name
- NCT03884335
- Testing
- laparoscopic radical prostatectomy
- Volunteers
- 45 people
- Sponsor
- Consorci Sanitari Integral
Hemodynamic Monitoring, Anesthesia; Adverse Effect
Hemodynamic Impact of Epidural Anesthesia in Relation to Age in Pediatric Patients.
Epidural analgesia is established as the gold standard in the management of post-surgical pain in multiple modalities, including the pediatric patient.
- Conditions
- Hemodynamic Monitoring, Anesthesia; Adverse Effect, Pediatric Major Surgery, Epidural Analgesia
- Trial name
- REHAEPP-2022 (NCT05543824)
- Testing
- Levobupivacaine
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Labour
Systematic Clonidine for Epidural Analgesia in Labour
In a prospective randomised study involving primiparous women in spontaneous uncomplicated labour with cervical dilatation < 5 cm, epidural analgesia will be given with an initial volume of 20 mL anaesthetic solution, followed by…
- Trial name
- NCT00983125
- Testing
- Clonidine
- Where
- France
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand