Clinical trials: Epidural Block
Labor Pain
Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
The combined spinal epidural (CSE) technique has become increasingly popular for labor pain because of its rapid onset and superior first stage analgesia.
- Trial name
- CEASE (NCT02062801)
- Testing
- Ephedrine
- Where
- United States
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Sharp HealthCare
Labor Pain
Programmed Intermittent Epidural Bolus Time Interval and Injection Volume
Studies suggest that administration of maintenance epidural solutions as programmed or automated intermittent boluses, rather than continuous infusions, result in lower bupivacaine consumption, decreased need for manual boluses…
- Trial name
- NCT00417027
- Testing
- Programmed Intermittent Epidural Bolus (PIEB)
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Surgical Anesthesia, Cesarean Section
Comparison of Chloroprocaine vs Lidocaine for Epidural Anesthesia in Cesarean Delivery
Regional anesthesia is commonly used for elective and emergency cesarean delivery. It provides numerous safety advantages when compared to general anesthesia for both the mother and fetus1.
- Trial name
- NCT03414359
- Testing
- 2% Lidocaine, 3% Chloroprocaine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Labor Pain
The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia
The purpose of this study is to determine the ideal dosage of intrathecal morphine for intra and post partum analgesia, while minimizing the side effect profile.
- Trial name
- NCT01146457
- Testing
- Morphine, Saline
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Beth Israel Deaconess Medical Center
Colon Cancer, Rectal Cancer
Compare Preperitoneal Analgesia to Epidural Analgesia for Pain Control After Colon and Rectal Surgery
This is a prospective randomized study of 114 patients. The purpose of this study is to compare the efficacy of two standard methods of analgesia for pain control in patients undergoing elective colon and rectal surgery, as…
- Conditions
- Colon Cancer, Rectal Cancer, Colonic Diverticulosis
- Trial name
- NCT01552226
- Testing
- Continuous Preperitoneal Analgesia, Continuous Epidural Analgesia
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Trinity Health Michigan
Pregnancy
Use of Peanut Labor Ball Following Epidural Anesthesia
The purpose of the study is to look at the impact of using the Peanut Labor Ball (PLB) after epidural anesthesia in patients who have never given birth.
- Trial name
- NCT02190591
- Testing
- Peanut Labor Ball
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Gastrostomy
Transversus Abdominis Plane Block on Stress Response
This study evaluates the effect of transversus abdominis plane(TAP) block combined with general anesthesia on perioperative stress response in patients undergoing radical gastrectomy.
- Trial name
- NCT03035916
- Testing
- Transversus abdominis plane block, Epidural anesthesia, control
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Jilin University
Labor Pain, Pregnancy
The Association Between Decreasing Labor Analgesia Epidural Infusion and Forceps Delivery
The objective of this study will be to compare epidural infusion management, specifically looking at infusion rate changes, in patients who receive forceps deliveries versus normal spontaneous vaginal deliveries.
- Trial name
- NCT00443560
- Testing
- Case controlled analysis of epidural labor analgesia patterns
- Where
- United States
- Volunteers
- 2,162 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Unplanned Caesarean Section
Chloroprocaine 3% - Epidural Anesthesia in Unplanned Caesarean Section
The study evaluate the quality of epidural anaesthesia and the safety of Chloroprocaine HCl 3% compared with Ropivacaine HCl 0.75% in patients with an epidural catheter in situ undergoing unplanned Caesarean section.
- Trial name
- NCT02919072
- Testing
- Chloroprocaine, Ropivacaine
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Sintetica SA
Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery
Pulse Pressure and Post-epidural Fetal Heart Rate Changes
Epidural anesthesia, the most common method of pain control in labor, can contribute to alterations in maternal blood pressure and/or fetal heart rate changes.
- Trial name
- NCT02565485
- Testing
- Lactated Ringer's
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- MetroHealth Medical Center
Target Controlled Infusion (TCI), Thoracic Epidural Anesthesia
The Effect of Thoracic Epidural Anesthesia With Different Block Level on Propofol Induction
It is a prospective, randomized, placebo-controlled study to investigate the effect of TEA with different block level on propofol concentration during general anesthesia induction.
- Conditions
- Target Controlled Infusion (TCI), Thoracic Epidural Anesthesia, Block Level, Gastrointestinal Surgery
- Trial name
- NCT02135016
- Testing
- 1% lidocaine, 2% lidocaine, 0.9% normal saline
- Where
- China
- Volunteers
- 45 people
- Sponsor
- First Hospital of China Medical University
Pregnancy
Effects of Bupivacaine Induced Motor Blockade During the Second Stage of Labor
The aim of this study is to measure the effects of bupivacaine administered via epidural catheters on indices of motor blockade ascertained during the second stage of labor.
- Trial name
- BUP (NCT01621230)
- Testing
- Epidural Bupivacaine plus fentanyl, Epidural fentanyl
- Where
- United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center