Clinical trials: Episodic Memory
Emotion Regulation, Mood Induction
Effectiveness of Personal Relevance of Visual Autobiographical Stimuli in Positive Emotions Induction
Background: The ability to retrieve specific memories is a cognitive and emotional protective factor. Among the most effective techniques to generate autobiographical memories is the use of audio-visual stimuli, particularly…
- Conditions
- Emotion Regulation, Mood Induction, Autobiographical Memory, Ageing
- Trial name
- NCT04251104
- Testing
- Images' personal relevance effectiveness in objective and subjective mood recovery
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Mild Cognitive Impairment
Improvement of Memory in Mild Cognitive Impairment
The Clinical Trial will systematically examine the feasibility of remote, caregiver-led tACS for older adults with memory deficits and evaluate whether repeated tACS leads to sustained improvement of neuronal activity and memory…
- Trial name
- NCT05708001
- Testing
- transcranial alternating current stimulation (tACS), high-density electroencephalography (hdEEG), Montreal Cognitive Assessment (MoCA)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lucie Bréchet
Behavior, Health
Parent-Child Memory Study: Improving Future Thinking Among Mothers
Parents of children from impoverished communities are disproportionately more likely to engage in harsh physical discipline, which can lead to serious clinical outcomes, including suicidal ideation and attempts.
- Trial name
- NCT06145919
- Testing
- Episodic Future Thinking (EFT), Episodic Recent Thinking (ERT)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Mental Disorders
Effects of Emotion on Episodic Memory in Typically Developing Children and Children With Williams-Beuren Syndrome
It's well established in the literature that emotional events are more likely to be remembered than neutral events. Although this Emotional Enhancement of Memory (EEM) has been well demonstrated in the adult literature, little is…
- Trial name
- EEM-TAdev (NCT03688516)
- Testing
- Manipulation of valence and modality, Spatial and recognition memory, Source and content memory
- Where
- France
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Alcohol Drinking, Drinking Behavior
Neuroimaging Mechanisms by Which Memory and Glucocorticoids Promote Risky Drinking
The purpose of this study is to determine whether hydrocortisone biases formation of alcohol-related memories to potentiate drinking.
- Conditions
- Alcohol Drinking, Drinking Behavior, Episodic Memory, Long-term Memory
- Trial name
- NCT04896489
- Testing
- Hydrocortisone 20 MG
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia Cognition Autobiographical Memory Cognitive Remediation
Cognitive Remediation of Autobiographical Memory in Schizophrenia Using SenseCam®
The aim of the study is to assess the efficiency of SenseCam® in patients with schizophrenia by comparing two cognitive remediation methods of autobiographical memory.Patients and control participants will be invited to carry…
- Trial name
- RéMABSchiz (NCT02038465)
- Testing
- Questionary
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic
Acoustic Stimulation During Sleep: Effects on Memory and p-tau217 in MCI
The goal of this clinical trial is to determine whether acoustic stimulation during sleep can enhance slow-wave sleep (SWS), improve cognitive function, and reduce AD-related pathology in individuals with mild cognitive…
- Conditions
- Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic, Cognitively Unimpaired
- Trial name
- PAS-MCI (NCT07529015)
- Testing
- Plase-Locked Acoustic Stimulation during slow-wave sleep
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Behavior
Neural Mechanisms for Reducing Interference During Episodic Memory Formation
Healthy individuals from the University of Oregon and surrounding community will be recruited for participation in behavioral, fMRI and eye tracking experiments that investigate human memory.
- Trial name
- NCT05092100
- Testing
- Visual stimulus similarity, fMRI, Eye tracking
- Where
- United States
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Aging
Modulation of Episodic Memory Using Theta Burst Stimulation (TBS)
The goal of this study is to evaluate the effect of white matter guided theta burst stimulation on episodic memory task performance in healthy older adults.
- Trial name
- NCT03406195
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Child, Only, Narration
Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Background and study aims: The Eye Movement Desensitization and Reprocessing Group Protocol with Children (EMDR-GP/C) was first developed by Korkmazlar following the Marmara earthquake in Turkey in 1999 and can be adapted for…
- Conditions
- Child, Only, Narration, Memory Dysfunction, Distress, Emotional
- Trial name
- HTC (NCT05319002)
- Testing
- Group EMDR
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Test Anxiety
Influence of Chocolate With Plant Additives on Episodic Memory in Healthy Subjects Experiencing Test Anxiety
Randomized, blind parallel group design. Single intake of 55 g high Epicatechin /Melissa dark chocolate containing 160 mg Epicatechin per 55 g serving or single intake of 55 g low Epicatechin/ oat bran white chocolate containing…
- Trial name
- MaRS-Basel (NCT03382067)
- Testing
- High Epicatechin/ Melissa, Low Epicatechin/ Oat bran
- Where
- Switzerland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Healthy
Efficacy, Transfer, and Neuro-functional Basis of a Memory Training Targeting Episodic Retrieval in Older Adults.
Aging leads to cognitive changes that affect memory, particularly episodic retrieval. These impairments are detrimental to seniors' quality of life.
- Trial name
- SPECTRA (NCT06110234)
- Testing
- Episodic Specificity Induction, Associative Memory
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Multiple Sclerosis, Relapsing-Remitting, Healthy Controls
The Relationships Between Personal Identity, Autobiographical Memory and Future Thinking in People With Multiple Sclerosis
Personal identity is composed of multiple facets of the self that are constructed and nourished through memories of past experiences (i.e., autobiographical memory) and the imagination of events that may occur in the future…
- Trial name
- SELFSEP (NCT05648292)
- Testing
- Neuropsychological tests and psychological questionnaires
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Healthy Volunteers
Contextual Associations During Episodic Recall of Everyday or Virtual Reality
The project is dedicated to development of new paradigms to investigate memory and attention in the rich and realistic environments.
- Trial name
- BREAL (NCT03286387)
- Testing
- Functional brain imaging without any contrast agent
- Where
- France
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Huntington Disease, Autobiographical Memory
Autobiographical Memory, Future Thought, and Eye Movements in Huntington's Disease
Huntington's disease (HD) is a hereditary neurodegenerative disorder characterized by progressively worsening motor, cognitive, psychiatric, and behavioral deficits.
- Trial name
- MAMOC-MH (NCT07409597)
- Testing
- neuropsychological tests, Eye tracker use
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Behavior
The Effects of Mindfulness Meditation on Brain Metabolism in the Limbic Regions Studied by Magnetic Resonance Spectroscopy
Stress reduction methods based on mindfulness meditation have been experiencing significant growth in various fields of society over the past twenty years.
- Trial name
- MEMOREM (NCT05710250)
- Testing
- 6-week MBSR program, 6-week muscular relaxation program
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Down Syndrome, Intellectual Disability
Down Syndrome Memantine Follow-up Study
The purpose of this research study is to learn if the medication Memantine Hydrochloride (the study medication) can help adolescents and young adults with Down syndrome. Dr.
- Trial name
- NCT02304302
- Testing
- Memantine
- Where
- 2 sites in United States, Brazil
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Multiple Sclerosis
Influence of Emotional Disorders and Executive on the Components Retrograde and Anterograde Episodic Memory in MS
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system responsible for physical disability but can also cause cognitive disturbances annoying social and professional life of patients with the disease.
- Trial name
- ITEMS (NCT02518776)
- Testing
- Neuropsychological tests
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Alzheimer Disease, Early Onset, Atypical Alzheimer's Disease
Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease
Alzheimer's disease (AD) is the leading neurodegenerative disease of aging characterized by multiple cognitive impairments. Given the recent failures of disease-modifying drugs, the current focus is on preventing or mitigating…
- Conditions
- Alzheimer Disease, Early Onset, Atypical Alzheimer's Disease, Logopenic Progressive Aphasia
- Trial name
- NCT04122001
- Testing
- Active, in-person HD-tDCS or active remote tDCS, Word List Learning Intervention (WordLLI)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Infant Nutrition Disorders, Health Behavior
Sharing Histories: Test of a Teaching Method for Community Health Workers
The purpose of this study is to determine the effectiveness of an innovative methodology for training Community Health Workers that will improve their effectiveness in educating mothers to adopt best practice health behaviors in…
- Trial name
- NCT02903602
- Testing
- Sharing Histories training method for CHW, Standard training method for CHW
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Future Generations Graduate School