Clinical trials: Episodic Migraine
Migraine With Aura, Migraine Without Aura
Trial Designs for Evaluating Migraine Treatment
The study aims to test interactions between drug and placebo-responses in acute migraine treatment and to assess variation in adverse events according to treatment information provided.
- Conditions
- Migraine With Aura, Migraine Without Aura, Headache, Migraine
- Trial name
- NCT06617832
- Testing
- Active drug for acute migraine treatment
- Where
- 2 sites in Denmark
- Volunteers
- 128 people
- Sponsor
- University of Aarhus
Migraine
Migraine is Associated With Altered Mechanical Pain Sensitivity. This Study Investigates Mechanical Pain Sensitivity, Headache Burden, and Quality of Life in Episodic and Chronic Migraine, Comparing Pressure Algometry and Algopeg® and Assessing Mechanosensitivity of Peripheral Nerves.
Migraine is one of the most prevalent neurological disorders and is associated with a substantial individual and societal burden.
- Trial name
- MechSens_Migra (NCT07559565)
- Testing
- pressure pain algometry
- Where
- Austria
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bernhard Taxer
Migraine Disorders, Headache Disorders
Idebenone for the Preventive Treatment of Migraine
Idebenone improves energy metabolism similarly to Coenzyme Q10, which is effective in migraine prophylaxis. The investigators compare idebenone (90 mg/day, 270 mg/day) and placebo in 180 migraine patients in a double-blind…
- Trial name
- NCT04151472
- Testing
- 90mg Idebenone, 270mg Idebenone
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Episodic Migraine
The Effects of Vitamin D Plus Omega-3 Polyunsaturated Fatty Acids in Patients With Episodic Migraine
First, the aims of this study are to explore the effect of vitamin D versus placebo in the prevention of episodic migraine. Second, we would like to compare and evaluate the effect of vitamin D plus omega-3 fatty acids versus…
- Trial name
- NCT05449145
- Testing
- Vitamin D, Non-Vitamin D
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kuang Tien General Hospital
Migraine
Comparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With Migraine
A migraine is a moderate to severe headache on one side of the head that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms.
- Trial name
- ATO-TOPIRAMATE (NCT05748483)
- Testing
- Atogepant, Topiramate
- Where
- 81 sites in Austria, Belgium and 10 more
- Volunteers
- 545 people
- Sponsor
- AbbVie
Chronic Migraine
Hypothalamus Connectivity in Chronic and Episodic Migraine
The purpose is to compare, using functional magnetic resonance imagery in resting-state, the connectivity of the hypothalamus in 2 groups of migraineurs.
- Trial name
- HYPOTHAMIG (NCT02328976)
- Testing
- functional Magnetic Resonance Imaging (fMRI)
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Toulouse
Cluster Headache - Episodic and Chronic, Migraine Headache
Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study
Migraine and/or Cluster Headache: Study Overview Background: Migraine and cluster headache are two primary headache disorders that significantly impact quality of life and functionality in those affected.
- Conditions
- Cluster Headache - Episodic and Chronic, Migraine Headache, Migraine Headache, With or Without Aura, Migraine in Adults
- Trial name
- NCT07292090
- Testing
- Intervention yogabased movements
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet