Clinical trials: Erectile Dysfunction
Erectile Dysfunction
IT Matters: The Erectile Restoration Registry
The objective of the It MATTERS registry is to collect Real-World Data (RWD) to monitor the safe and effective use of commercially available Boston Scientific Corporation (BSC) penile prostheses
- Trial name
- NCT04200937
- Testing
- Tactra Malleable, Spectra™ Concealable Penile Prothesis, AMS Ambicor™ Inflatable Penile Prosthesis
- Where
- 25 sites in United States, China and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Erectile Dysfunction
A Phase 1 Trial of LIB-01 in Healthy Participants.
The goal of this clinical trial is to learn about the safety, tolerability and pharmacokinetics of LIB-01 in healthy male participants.
- Trial name
- NCT06324006
- Testing
- LIB-01
- Where
- Sweden
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Dicot AB
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Erectile Dysfunction
A Phase I Crossover Study of the Hemodynamic Interactions of Avanafil & Alcohol in Healthy Male Subjects.
The purpose of this study is primarily to evaluate whether taking avanafil with alcohol causes the blood pressure to fall.
- Trial name
- NCT01054859
- Testing
- avanafil, alcohol
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Erectile Dysfunction
Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Versus To Viagra® Oral Tablet.
This study will evaluate if an orally disintegrating tablet of sildenafil will have similar pharmacokinetic properties as the conventional tablet of sildenafil.
- Trial name
- NCT01254383
- Testing
- Sildenafil Tablet, Sildenafil ODT
- Where
- Singapore
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Evaluating the Efficacy of Platelet-Rich-Plasma (PRP) for Erectile Dysfunction
There is great interest in restorative therapies (platelet-rich plasma (PRP) injections, shockwave therapy and stem cell therapy) for ED given their non-invasive nature.
- Trial name
- NCT06264635
- Testing
- Platelet-Rich-Plasma, Saline
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Erectile Dysfunction
TRIP-Patch vs the Rigiscan
In men without erectile problems, night time erections occur during the REM-sleep. For this study the current diagnostic test, the Rigiscan is compared, with the data from the TRIP-Patch during the night.
- Trial name
- TRIP-Patch (NCT05219071)
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Prostate Cancer Adenocarcinoma, Erectile Dysfunction Following Radical Prostatectomy
Use of Indocyanine Green in Robotic Prostate Surgeries
Imaging of the vascular nerve bundle using Indocyanine Green
- Trial name
- NCT05960149
- Testing
- using Indocyanine Green, Nerve-sparing robot-assisted laparoscopic radical prostatectomy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Impotence
Use of Sildenafil (Viagra) in Diabetic Men With Erectile Dysfunction: the Impact on Blood Vessels
To evaluate the impact of nightly sildenafil vs placebo use on diabetic men with and without proven endothelial dysfunction and coexisting erectile concerns.
- Trial name
- NCT00199563
- Testing
- Viagra
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Erectile Dysfunction
Endocan Level in Patients With Erectile Dysfunction and Relationship With Tadalafil Treatment
The investigators analyze the patients' endocan levels, IIEF scores, and hormon levels both before and after tadalafil (5 or 20mg) treatment.
- Trial name
- NCT05109377
- Testing
- Endocan, tadalafil
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Vasculogenic Erectile Dysfunction
Intracavernosal Injection of Botulinum Toxin Type A in the Treatment of Vascular Erectile Dysfunction
Evidence has been arising that Botulinum toxin injections can relax smooth muscles fibers in the treatment of obesity and hyperactive bladder.
- Trial name
- NCT02584686
- Testing
- Botulinum Toxin Type A, Normal Saline
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Daily Tadalafil in Diabetic ED Patients
This study evaluates the effect of 5 mg daily tadalafil therapy on serum levels of Endothelin-1 and E-selectin in diabetic male patients with erectile dysfunction.
- Trial name
- NCT06962462
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Erectile Dysfunction
Feeling Hot 2: Penile Skin Temperature Measurements of Nocturnal Erections
The Feeling Hot studies focus on the proof-of-principle of using temperature sensing as a tool to detect nocturnal erections. In the Feeling Hot 2 study the penile skin temperature is investigated during nocturnal erections…
- Trial name
- NCT05183620
- Testing
- Feeling Hot sensor system
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Androgen Deficiency, Depressive Symptoms
Physical Exercise for Men With Andropause
The aim of this study is to analyze the impact of physical exercise through a protocol of concurrent training in the psychological, physical, hormonal and sexual aspects in middle aged men with androgen deficiency in the aging…
- Conditions
- Androgen Deficiency, Depressive Symptoms, Stress, Psychological, Abdominal Obesity
- Trial name
- DAEM (NCT03150225)
- Testing
- Concurrent training, Eurycoma longifolia
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Laboratório de Pesquisa em Lazer e Atividade Física
Erectile Dysfunction
A Study of Visual Effects of Erectile Dysfunction Medications Dosed Daily for Six Months
This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the effects on vision of six months of daily dosing of 5 mg tadalafil or 50 mg sildenafil compared with placebo.
- Trial name
- NCT00333281
- Testing
- tadalafil
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Erectile Dysfunction
Feeling Hot 1: Environmental Influences of Overnight Measurement on Skin Temperature of the Erectile Penis
The Feeling Hot studies focus on the proof-of-principle of using temperature sensing as a tool to detect nocturnal erections. In the Feeling Hot 1 study the influence of environmental factors of overnight measurements are studied…
- Trial name
- NCT05183581
- Testing
- Feeling Hot sensor system
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Erectile Dysfunction
Effect of Lifestyle Changes on Erectile Dysfunction in Obese Men: a Randomized Controlled Trial
Healthy lifestyle factors are associated with maintenance of erectile function in men. To determine the effect of weight loss and increased physical activity on erectile and endothelial functions in obese men.
- Trial name
- NCT00636688
- Testing
- Lifestyle - detailed advice, Control - general information
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Erectile Dysfunction
Changes in Penile Firmness With Low-Intensity Shockwave Therapy (LiST)
Patients presenting with erectile dysfunction are often found to have increased corporal firmness on elastography. We hypothesize that this corporal firmness reflects reversable changes that can be altered by Low-Intensity…
- Trial name
- NCT05756803
- Testing
- Low-intensity acoustic shockwave therapy
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Erectile Dysfunction
Diagnostic Performance of a Flexible Penile Monitoring System for ED
This study aims to evaluate the diagnostic performance of a novel intelligent flexible penile monitoring system for erectile dysfunction (ED).
- Trial name
- NCT07762469
- Testing
- Intelligent Flexible Penile Monitoring System, RigiScan Plus
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bin Xu
Erectile Dysfunction, Inflammation
Effects of Tadalafil on LMR and MHR in Patients With ED
The aim of the study was to investigate whether daily 5 mg tadalafil over eight weeks affects to Lymphocyte/Monocyte ratio (LMR) and Monocyte/High-Density Lipoprotein ratio (MHR) in patients with erectile dysfunction (ED).
- Trial name
- NCT03918993
- Testing
- Tadalafil 5mg tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Samsun Liv Hospital