Clinical trials: Erectile Dysfunction (ED)
Erectile Dysfunction
Phase 2 Efficacy Study of Sildenafil Products in Adult Men With Erectile Dysfunction
The goal of this clinical trial is to learn how different sildenafil-based erectile dysfunction (ED) treatments affect erectile function in adult men.
- Trial name
- NCT07231185
- Testing
- Hezkue, Hezkue Turbo, Galotam
- Volunteers
- 200 people
- Sponsor
- Aspargo Labs, Inc
Erectile Dysfunction
Differential Plasma MicroRNA Profiles in ED and Normal Erectile Function in Older Males
Erectile dysfunction (ED) is strongly associated with aging. With the rapidly expanding aging population and the increase in life expectancy, an increase in the prevalence of ED is expected in the years to come.
- Trial name
- NCT01830049
- Testing
- Take blood
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Radical Prostatectomy, Erectile Dysfunction Following Radical Prostatectomy
EVERiST: Impact of Image Detected Accessory Pudendal Artery on Erection Recovery After Nerve Sparing Prostatectomy
Prostate cancer is the most common cancer amongst men in the United Kingdom, and two common curative treatments are surgery to remove the prostate (radical prostatectomy) or radiotherapy.
- Conditions
- Radical Prostatectomy, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Due to Arterial Insufficiency, Robotic Radical Prostatectomy
- Trial name
- EVERiST (NCT07597798)
- Testing
- Robotic Radical Prostatectomy, Penile doppler ultrasound
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University College, London
Erectile Dysfunction
Bone Marrow Mesenchymal Stem Cells in Erectile Dysfunction (ED)
Recovery of erectile function using bone marrow mesenchymal stem cells (MSCs) after in vitro expansion under restricted culturing conditions.
- Trial name
- NCT02945462
- Testing
- autologous mesenchymal stem cells
- Volunteers
- 4 people
- Sponsor
- University of Jordan
Erectile Dysfunction
Long-Term Safety and Efficacy Study of Avanafil in Men With Erectile Dysfunction
This open-label study is being conducted to evaluate the long-term safety, tolerability, and efficacy of avanafil in men with mild to severe erectile dysfunction.
- Trial name
- NCT00853606
- Testing
- avanafil
- Where
- 40 sites in United States
- Volunteers
- 712 people
- Sponsor
- VIVUS LLC
Erectile Dysfunction
6 vs 12 Sessions in Low Intensity Extracorporeal Shock Wave Treatment (LI-ESWT) for Erectile Dysfunction (ED)
The present study aims to identify and compare the efficacy and safety of two different session frequency protocols (once vs twice per week) of low intensity extracorporeal shockwave treatment (LI-ESWT) using Aries ED device, in…
- Trial name
- NCT03089307
- Testing
- Dornier Aries- ED device
- Where
- Greece
- Volunteers
- 44 people
- Sponsor
- Institute for the Study of Urological Diseases, Greece
Organic Erectile Dysfunction
Assessment of Penile Vibratory Stimulation Using the Viberect in Men With Mild-Moderate ED
The primary objective of this study is to assess the safety, acceptability, and satisfaction of penile vibratory stimulation in treatment of erectile dysfunction (ED).
- Trial name
- NCT01715571
- Testing
- Viberect
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Erectile Dysfunction
Vardenafil Orodispersible Tablet (ODT) Versus Placebo in Males With Erectile Dysfunction, 50% of Whom Are to be 65 Years or Older.
This study investigates the safety and efficacy of a new dosage form of Vardenafil, an orodispersible tablet (ODT), and compares it to the safety and efficacy of a placebo (inactive) tablet in the treatment of erectile…
- Trial name
- NCT00655629
- Testing
- Vardenafil ODT (STAXYN, BAY38-9456)
- Where
- 40 sites in United States, Australia and 2 more
- Volunteers
- 339 people
- Sponsor
- Bayer
Erectile Dysfunction
Efficacy of Intracavernosal as add-on Therapy to Sildenafil 100 mg on Demand Compared to Sildenafil 100 mg on Demand for the Treatment of Erectile Dysfunction (ED) Not Sufficiently Responsive to Standard Therapy With Phosphodiesterase Type 5 Inhibitors
The primary objective of this study is to investigate the efficacy of intracavernosal (Xeomin®) (100U) as add-on therapy to sildenafil 100 mg on demand in men with ED and insufficient response to standard therapy with 100 mg…
- Trial name
- MENOX (NCT05196308)
- Testing
- Investigational product administration Xeomin® (MERZ PHARMACEUTICALS GMBH)
- Where
- France
- Volunteers
- 226 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Erectile Dysfunction, Sexual Dysfunction, Physiological
Study to Compare the Tolerability and Efficacy of Once Daily Vardenafil vs Vardenafil PRN vs Placebo in Men Immediately After Nerve-sparing Prostatectomy for Improving ED
A study to assess the efficacy of vardenafil, taken as a tablet both nightly or 'as needed' (immediately before intended sexual activity) compared to placebo, to evaluate its tolerability and if it can help in recovery of…
- Trial name
- NCT00492635
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 86 sites in United States, Austria and 13 more
- Volunteers
- 628 people
- Sponsor
- Bayer
Erectile Dysfunction
A Study Evaluating Vardenafil Compared to Placebo in Subjects With Erectile Dysfunction (ED) and Dyslipidemia
This is a study consisting of four periods (screening, run-in, treatment, follow-up). A four-week treatment-free, run-in period where the subject will make at least four attempts at intercourse on four separate days with at least…
- Trial name
- NCT00379756
- Testing
- LEVITRA (vardenafil)
- Where
- 65 sites in United States
- Volunteers
- 395 people
- Sponsor
- GlaxoSmithKline
Erectile Dysfunction, Diabetes Mellitus, Type 2
Effect of ESWT on ED in Type 2 Diabetics
Diabetes mellitus (DM) is known not only for its widespread prevalence, but also for its significant complications including cerebrovascular disease, coronary artery disease, renal failure, vision loss, and neuropathy.
- Trial name
- NCT04219462
- Testing
- active extracorporeal shock wave
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Erectile Dysfunction
Clinical Trial Studying the Efficacy and Safety of IP2018 in Depressed, Erectile Dysfunction (ED) Patients
This is a Phase IIa, randomised, double-blind, placebo-controlled, 3-period, crossover study to assess two single oral dose levels of IP2018. It is planned to enrol 24 patients.
- Trial name
- NCT04686916
- Testing
- IP2018
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Initiator Pharma
Erectile Dysfunction
Extracorporeal Shock Wave Therapy With a Wide Focus Probe for the Treatment of Erectile Dysfunction
Low intensity shockwaves (1/10 the ones used in Lithotripsy) are delivered to the penile tissue. Shockwaves are created by a special generator and are focused using a specially designed shockwave applicator apparatus.
- Trial name
- NCT01317693
- Testing
- Low intensity shock waves
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Rambam Health Care Campus
Erectile Dysfunction, Erectile Dysfunction (ED)
Satisfaction of Patients With Erectile Dysfunction With the Use of Sildenafil Oral Suspension Compared to Orodispersible Tablets
The goal of this observational retrospective study is to to evaluate treatment satisfaction with sildenafil oral suspension in patients with mild-to-moderate ED who were previously taking orodispersible sildenafil.
- Trial name
- SILOROS (NCT07676617)
- Testing
- Sildenafil Oral Suspension Compared to Orodispersible Tablets
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Erectile Dysfunction, PRP
Platelet-rich Plasma(PRP) Injection in ED
RPR contains rich-in growth factors and has the properties of helping tissue regeneration and nerve repair. In theory, it is possibility of curing ED.
- Trial name
- NCT05241964
- Testing
- PRP
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Erectile Dysfunction
Clinical Investigation Using MED3000 Gel or Tadalafil Tablets in the Treatment of Erectile Dysfunction
An open-label investigation using MED3000 gel or tadalafil (5 mg) tablets in the treatment of erectile dysfunction in patients from 22 to 70 years of age. Each patients will be expected to participate for up to 30 weeks.
- Trial name
- NCT04984993
- Testing
- MED3000 (Male), Tadalafil 5mg (Male), MED3000 (Female)
- Where
- 18 sites in United States, Bulgaria and 2 more
- Volunteers
- 116 people
- Sponsor
- Futura Medical Developments Ltd.
Erectile Dysfunction, Localized Prostate Carcinoma
LiSWT for Nerve Sparing Radical Prostatectomy ED
This phase I clinical trial studies how well low intensity shockwave therapy (LiSWT) improves erectile function in patients who have had nerve-sparing radical prostatectomy (NS-RP), a type of surgery that attempts to save the…
- Conditions
- Erectile Dysfunction, Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8
- Trial name
- NCT05877144
- Testing
- Nerve-Sparing Prostatectomy, Medical Device Usage and Evaluation, Duplex Ultrasound
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Thomas Jefferson University
Erectile Dysfunction
The Effect of Low Intensity Shockwave Therapy for ED in Post Radical Prostatectomy Patients Who Didn't Respond to PDE5i
Low Intensity Shock Wave Therapy (LI-ESWT) was shown to have a beneficial effect on ED patients responding to PDE5i's. This study aimed to determine the capability of LI-ESWT to affect patients who underwent radical prostatectomy…
- Trial name
- LI-ESWT (NCT01274949)
- Testing
- LI-ESWT
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Erectile Dysfunction (ED)
Efficacy Study of RX-10100 to Treat Erectile Dysfunction (ED)
The primary objective of this Phase IIa trial is to determine the effective doses and treatment period for an upcoming RX-10100 Phase IIb trial in subjects with erectile dysfunction (ED).
- Trial name
- NCT00693056
- Testing
- RX-10100 5mg, RX-10100 10mg, RX-10100 15mg
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Rexahn Pharmaceuticals, Inc.