Clinical trials: Error, Refractive
Myopia, Myopic Astigmatism
SUPRACOR for Myopia and Myopic Astigmatism
This clinical study has been planned to evaluate the safety and effectiveness of the SUPRACR presbyopic excimer laser treatment algorithm for myopic eyes developed for applying to the cornea of the human eye in a single center.
- Conditions
- Myopia, Myopic Astigmatism, Presbyopia
- Trial name
- SUPRACOR (NCT01404884)
- Testing
- SUPRACOR
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Technolas Perfect Vision GmbH
Cataract, Presbyopia
A Clinical Evaluation of the LensGen Intraocular Lens
A multi-center, open-label, non-comparative clinical trial to assess the safety and efficacy of the LensGen IOL (Juvene IOL) for the treatment of aphakia and presbyopia after removal of the natural crystalline lens due to…
- Trial name
- Grail (NCT05364658)
- Testing
- Juvene IOL
- Where
- 2 sites in Mexico
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- LensGen, Inc.
Choroidal Neovascularisation
Ranibizumab for the Treatment of Choroidal Neovascularisation (CNV) Secondary to Pathological Myopia (PM): an Individualized Regimen
This study is designed to provide efficacy and safety data in patients with choroidal neovascularisation (CNV) secondary to myopia using an individualized as-needed (PRN) dosing schedule.
- Trial name
- REPAIR (NCT01037348)
- Testing
- ranibizumab 0.5mg
- Where
- 12 sites in United Kingdom
- Volunteers
- 65 people
- Sponsor
- Novartis
Teenagers, Myopia
Visual and Postural Behavior in Myopic and Non-Myopic Teenagers
The goal of this observational study is to learn whether different types of eyeglasses prescription and different types of lenses change how close teenagers hold objects when looking at them up close.
- Trial name
- CALYPSO (NCT07440134)
- Testing
- Ophtalmic measurements, Visuo-postual measurements
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Essilor International
Presbyopia
Phase 1/2 Study of AGN-241622 in Healthy Participants and Participants With Presbyopia
The objective of this study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of AGN-241622 ophthalmic solution for the first time in human participants
- Trial name
- NCT04403763
- Testing
- AGN-241622, Vehicle
- Where
- 10 sites in United States
- Volunteers
- 80 people
- Sponsor
- AbbVie
Presbyopia
Evaluate the Efficacy and Safety of CTO0307 in Adults With Presbyopia
This study was to compare the presbyopia correction effect between the treatment group and the control group, evaluated by the proportion of patients who achieved an improvement of 3 lines or more in mesopic binocular DCNVA at…
- Trial name
- NCT07723716
- Testing
- CTO0307 Eye drop
- Where
- South Korea
- Volunteers
- 167 people
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Myopia, Pathological
VEGF Trap-Eye in Choroidal Neovascularization Secondary to Pathologic Myopia (mCNV)
VEGF Trap-Eye will be tested for safety and efficacy in patients with vision loss due to choroidal neovascularization secondary to pathologic myopia. This will be a placebo-controlled trial.
- Trial name
- Myrror (NCT01249664)
- Testing
- VEGF Trap-Eye (BAY86-5321), No Drug
- Where
- 20 sites in Hong Kong, Japan and 3 more
- Volunteers
- 122 people
- Sponsor
- Bayer
Presbyopia
Comparing the Performance of 1 Day Multifocal Contact Lenses
The objective of the study was to compare the lens handling and performance of Lens A to habitually worn multifocal contact lenses and to the competitor Lens B.
- Trial name
- NCT04449263
- Testing
- Lens A, Lens B, Habitual Lenses
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Astigmatism, Myopia
Effect of Head and Gaze Position on Soft Toric Contact Lens Performance
Primary Hypotheses: Senofilcon A will provide significantly less rotation with subjects in a recumbent position than Filcon II 3 monthly .
- Trial name
- NCT01579045
- Testing
- senofilcon A, etafilcon A, nelfilcon A
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
A Bilateral Dispensing Clinical Trial of an Sapphire Lens Against Senofilcon A Toric for Astigmatism Lens
This study was conducted to evaluate the clinical performance of an investigational silicone-hydrogel lens against Senofilcon A toric lens. The study results were not used for design validation of the investigational product.
- Trial name
- NCT02555098
- Testing
- Sapphire contact lenses, senofilcon A contact lenses
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- CooperVision, Inc.
Myopia
Post-market Follow Up Study on Paragon CRT® 100 (Paflufocon D)
The main objective of this post market clinical study is to evaluate the effectiveness and safety of the Paragon CRT®100 Contact Lens.
- Trial name
- NCT04187599
- Testing
- Paragon CRT®100 Contact Lens
- Where
- 4 sites in China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Hyperopia, Myopia
Clinical Study of Clariti Monthly Contact Lens
A clinical study report follows; this clinical study evaluated the safety and efficacy of SAUFLON CLARITI Soft Silicone Hydrogel Contact Lens with UV Blocker by comparison with Air Optix Aqua silicone hydrogel contact lenses…
- Trial name
- NCT01392950
- Testing
- Air Optix Aqua, Clariti
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sauflon Pharmaceuticals Ltd
Myopia
Evaluation Of One Silicone Hydrogel Contact Lens and Two Hydrogel Lenses in Daily Wear
To evaluate the comparative clinical performance of the fanfilcon A silicone hydrogel lens used in daily wear and to compare this with competitive hydrogel lens products.
- Trial name
- NCT04050618
- Testing
- fanfilcon A test lens, ocufilcon D control lens, etafilcon A control lens
- Where
- 6 sites in United States
- Volunteers
- 114 people
- Sponsor
- CooperVision, Inc.
Refractive Errors
Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens
The objective of this clinical investigation is to collect valid scientific safety and effectiveness data on the Acuity 200 (fluoroxyfocon A) Rigid Gas Permeable Contact Lens, manufactured from a newly developed rigid gas…
- Trial name
- Acuity 200 (NCT03971227)
- Testing
- Acuity 200 (Fluoroxyfocon A) contact lens, Acuity 100 (Hexafocon A) contact lens
- Where
- 3 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Acuity Polymers, Inc.
Myopia
Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)
Myopia, or shortsightedness, is a multifactorial disorder, governed by environmental and genetic factors. Myopia is the most common ocular disorder worldwide with an increasing prevalence over the past few decades and affecting…
- Trial name
- MODERATO (NCT07028827)
- Testing
- 0.05% atropine eye drops, 0.025% atropine eye drops
- Where
- 11 sites in Albania, Italy and 3 more
- Volunteers
- 234 people
- Sponsor
- Ocus Innovation Ireland Limited
Astigmatism
Clinical Performance of Habitual Hydrogel vs. Silicone Hydrogel Toric Contact Lenses
Evaluate the clinical performance of existing wearers of hydrogel toric lenses when refitted with Avaira toric silicone hydrogel contact lenses over 1 week of wear.
- Trial name
- NCT02142361
- Testing
- enfilcon A
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Ametropia
Clinical Performance of Two Daily Disposable Toric Soft Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1™ for Astigmatism (P1fA) contact lenses with 1-DAY ACUVUE MOIST® for ASTIGMATISM (AMfA) contact lenses.
- Conditions
- Refractive Errors, Ametropia, Astigmatism
- Trial name
- NCT04908488
- Testing
- Verofilcon A toric contact lenses, Etafilcon A toric contact lenses
- Where
- 8 sites in United States
- Volunteers
- 115 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Daily Disposable Toric Comparative Trial in Europe
The purpose of this study is to investigate the subjective and objective performance of two daily disposable lenses for wearers with astigmatism.
- Trial name
- NCT01070381
- Testing
- nelfilcon A contact lens, ocufilcon D contact lens
- Volunteers
- 220 people
- Sponsor
- CIBA VISION
Astigmatism
Clinical Evaluation of Two Toric Contact Lenses
The study objective was to compare short-term clinical performance data of two toric contact lenses.
- Trial name
- NCT05688657
- Testing
- Lens A, Lens B
- Where
- Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Evaluation of the Safety and Efficacy of Yung Sheng 38% Color Contact Lens
This was a single group, open-label clinical study to assess the safety and efficacy of Yung Sheng 38% color contact lens for vision correction.
- Trial name
- NCT06128473
- Testing
- Soft Contact Lens
- Volunteers
- 71 people
- Sponsor
- Yung Sheng Optical Co., Ltd.