Clinical trials: Error, Refractive
Presbyopia Correction, Visual Impairment and Blindness (Excl Colour Blindness)
Effect of Presbyopia Correction on Livelihood and Repayment Among Solar Customers in Western Region, Kenya
With age, people lose the ability to see things that are near them clearly. This is known as presbyopia. Although this is a normal ageing process, it can be corrected with near vision eyeglasses - colloquially known as reading…
- Conditions
- Presbyopia Correction, Visual Impairment and Blindness (Excl Colour Blindness), Repayment Behaviour, Livelihoods
- Trial name
- NCT06774183
- Testing
- Near vision glasses for presbyopia correction
- Volunteers
- 1,085 people
- Sponsor
- Dot Glasses Kenya
Myopia
Performance Evaluation of a New Daily Disposable Silicone Hydrogel Lens
The purpose of this study was to compare a new daily disposable, silicone hydrogel contact lens to marketed daily disposable, silicone hydrogel contact lenses.
- Trial name
- TUNGSTEN (NCT01371552)
- Testing
- delefilcon A contact lens, filcon II 3 contact lenses, narafilcon A contact lenses
- Where
- Canada
- Volunteers
- 119 people
- Sponsor
- CIBA VISION
Myopia
Two Week Cross-Over Study Comparing Two Daily Disposable Contact Lenses
This study seeks to evaluate and compare the clinical performance of two daily disposable soft contact lenses, Proclear 1 Day and 1-Day Acuvue Moist.
- Trial name
- NCT01155323
- Testing
- etafilcon A, omafilcon A
- Where
- Singapore
- Volunteers
- 118 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adults
Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 2 treatment visits.
- Trial name
- VISION-2 (NCT05114486)
- Testing
- Pilocarpine Ophthalmic administered with the Optejet dispenser
- Where
- 9 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Myopia, Large Language Model
Development and Validation of a Large Language Model-based Myopia Assistant System
Myopia is a rapidly growing global health concern, and there is an urgent need for advanced tools that can facilitate personalized healthcare strategies.
- Trial name
- NCT06607822
- Testing
- A patient-centered assistant system based on Large-Language Model (LLM)
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Astigmatism
VERION Versus Conventional, Manual Ink-marking in Toric IOL Implantation
OVERVIEW Cataract is a clouding of the crystalline lens which causes vision loss and blindness if untreated. Cataract surgery is the most frequently performed surgical intervention in medicine with an incidence of 880 surgeries…
- Trial name
- NCT02370953
- Testing
- VERION for toric IOL alignment, Conventional, manual ink-marking for toric IOL alignment
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Maastricht University Medical Center
Myopia
Atropine and Spectacle Combination Treatment (ASPECT): 12-month Results of a Randomized Clinical Trial for Myopia Control
Phase IV clinical trial to evaluate whether there is a significant difference in the control of myopia progression in myopic children treated with 0.025% atropine and DIMS spectacle lenses compared to 0.025% atropine and single…
- Trial name
- ASPECT (NCT06431841)
- Testing
- Atropine 0,025%, DIMS Lenses, Monofocal lenses
- Where
- Spain
- Volunteers
- 111 people
- Sponsor
- Hospital San Carlos, Madrid
Refractive Error
Effects of Optical Blur on Performance and Comfort of Computer Users
The aim of this study is to examine the relationship between optical blur from poor refractive corrections (glasses) of workers using computers and their productivity and comfort in the workplace.
- Trial name
- NCT00318045
- Testing
- Eyeglass lenses
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Vision Council of America
Hyperopia, Hypermetropia
Enhancement of Emmetropization in Hyperopic Infants
To determine if wearing a moderate spectacle under-correction (3.00D) and performing activities designed to stimulate accurate accommodation during a 15-month period will enhance emmetropization in highly hyperopic (between…
- Conditions
- Hyperopia, Hypermetropia, Farsightedness
- Trial name
- NCT00574717
- Testing
- Spectacles
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ohio State University
Presbyopia, Esotropia
Accommodation-Related Visual Training Combined with Transcranial Electrical Stimulation Versus Visual Training Alone for the Treatment of Accommodation Dysfunction
This is a single-center, randomized controlled trial to compare the effectiveness of transcranial electrical stimulation combined with visual training with visual training alone for the treatment of accommodation disorder…
- Trial name
- NCT06714890
- Testing
- Transcranial Electrical Stimulation, Visual Training
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Myopia
Effects of Projected Peripheral Defocus on Ocular Biometrics
Acucela Inc. intends to develop a medical device to significantly halt or reverse myopic progression, which is a significant public health concern across the world, especially in Asian demographics.
- Trial name
- NCT04388020
- Testing
- Tabletop prototype of eSpecs: Active projection of defocused image in the peripheral visual field, Tabletop prototype of eSpecs: No Active projection of defocused image in the peripheral visual field
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
High Myopia
Evaluation of the Prophylactic Use of Mitomycin C 0.02% to Inhibit Haze Formation After Photorefractive Keratectomy for High Myopia: 15 x 30 Seconds
To evaluate and compare the effect of the prophylactic use of two different exposure times of mitomycin C (MMC) 0.02% to inhibit haze formation after photorefractive keratectomy (PRK) for high myopia (> -7.0 D).
- Trial name
- BQ-01-07-ARVO (NCT00564213)
- Testing
- PRK and a single intraoperative topical application of mitomycin C 0.02% for 15 seconds
- Volunteers
- 36 people
- Sponsor
- Instituto de Olhos de Goiania
Cataract, Presbyopia
Retrospective Clinical Investigation of the Safety and Performance of 640PM Trifocal IOL Implantation in Patients With Cataract and/or Ametropia (Hyperopia, Myopia) and/or Presbyopia
The clinical investigation objective is to evaluate safety and performance outcomes of trifocal IOL implantation to improve vision in patients with cataract and/or ametropia (hyperopia, myopia) and/or presbyopia.
- Conditions
- Cataract, Presbyopia, Hyperopia, Myopia
- Trial name
- NCT05735990
- Testing
- Intraocular lens
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Medicontur Medical Engineering Ltd
Ametropia
Three-month Clinical Evaluation of Silicone Hydrogel Definitive 65 Contact Lenses
Comparison of different contact lens materials.
- Trial name
- NCT02249689
- Testing
- Definitive 65, Definitive 74
- Where
- 2 sites in Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Emmetropia, Myopia
Effects of Light on the Choroid and Pupil
Monochromatic light creates longitudinal chromatic aberration, with short wavelength blue light forming a focal point in front of the retina and long wavelength red light forming a focal point behind the retina.
- Trial name
- NCT05852782
- Testing
- White Light therapy, Blue light therapy, Red light therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Houston
Astigmatism, Myopia
Comparative Clinical Evaluation of Soft Toric Lens Designs
This study is evaluating the initial fit of toric contact lenses.
- Trial name
- NCT01552876
- Testing
- etafilcon A, nelfilcon A, Filcon II 3
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia, Refractive Error
Phase 3 Evaluation of the Safety and Efficacy of LNZ100 & LNZ101 for the Treatment of Presbyopia
Phase 3 study to evaluate the safety and effectiveness of LNZ100 \& LNZ101 for the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Error, Eye Diseases, Near Vision
- Trial name
- CLARITY 1 (NCT05656027)
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Brimonidine
- Where
- 25 sites in United States
- Volunteers
- 469 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Refractive Errors
Clinical Performance Evaluation of Two Daily Disposable Silicone Hydrogel Toric Contact Lenses
The purpose of this study is to evaluate the rotational behavior of DT1 Toric contact lenses.
- Trial name
- NCT04254003
- Testing
- DT1 Toric contact lenses, AO1DfA contact lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Alcon Research
Myopia
Effect of Increasing Time Spent Outdoors on Myopia Prevention in School-Aged Children in Northeast China
The purpose of this study is to develop a school-based intervention aimed at prevent the onset and development of myopia among school aged children by increasing time spent outdoors in northeast China.
- Trial name
- NCT02271373
- Testing
- increasing time spent outdoors
- Volunteers
- 3,521 people
- Sponsor
- Anhui Medical University
Myopia
LASIK Flap Thickness and Visual Outcomes Using the WaveLight FS200 Femtosecond Laser
The objective of this study is to evaluate the visual outcome, accuracy, predictability and complications of LASIK flap creation using the Alcon Wavelight FS200 Femtosecond laser and compare these results to those obtained using…
- Trial name
- FS200 (NCT02060461)
- Testing
- FS200 femtosecond laser LASIK, IntraLase femtosecond laser LASIK
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- The Cleveland Clinic
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