Clinical trials: Erythema
Erythema, Radiation Therapy, Secondary Skin Reactions
Evaluation of a Novel Amino Acid Based Moisturizing Cream as Part of the Daily Standard Skincare Regimen Recommended During Radiation Therapy
The goal of this clinical study is to evaluate a novel amino acid based moisturizing cream as part of the daily standard skincare regimen recommended during radiation therapy.
- Trial name
- NCT06016361
- Testing
- VS-200Cr, Standard of care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Entrinsic Bioscience Inc.
Healthy Volunteer Study
An Open-label, Non Significant Risk, Adhesive Wear Validation Study for the On Body Drug Delivery Device Component of the SQIN-01 Furosemide Infusor (Infusor Device)
The purpose of the present study is to test the adequacy, performance and skin reactivity of the adhesive tape to be utilized in the to-be-marketed Device.
- Trial name
- NCT04836572
- Testing
- 3M 1529 Adhesive Tape
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SQ Innovation, Inc.
Ocular Redness
A Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% With Sodium Hyaluronate Relative to Lumify in Adult Subjects With Ocular Redness
To demonstrate the efficacy of BTOS-HA as non inferior to Lumify for treating ocular redness in a population of adult subjects.
- Trial name
- NCT06803654
- Testing
- BTOS-HA, Lumify®
- Where
- 11 sites in United States
- Volunteers
- 578 people
- Sponsor
- Bausch & Lomb Incorporated
Erythema
Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Persistent Facial Erythema
The purpose of this study is to compare the efficacy and assess the safety of CD07805/47 gel 0.5% applied topically once daily for 29 days versus vehicle control, in subjects with moderate to severe chronic persistent vascular…
- Trial name
- NCT01882712
- Testing
- CD07805/47 Gel 0.5%
- Sponsor
- Galderma R&D
Pain
A Study to Assess Therapeutic Equivalence Between Test EMLA Patch With Marketed EMLA Patch in Healthy Subjects.
A double-blind, randomized, 2-period, placebo-controlled, single-center, crossover study, efficacy study demonstrating the therapeutic equivalence of the test cellulose disc (matrix) in EMLA patch and the current commercial…
- Trial name
- EMLA (NCT03313336)
- Testing
- EMLA test patch, EMLA current reference patch
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Arthritis, Rheumatoid
Study in Patients With Moderated to Severe Rheumatoid Arthritis Who Have Failed to Combination Therapy of Conventional Disease-modifying Antirheumatic Drugs (cDMARDs) to cDMARD Plus ANti-TNF Versus cDMARDs in Real World
This study will be conducted to observe the disease activity change of Conventional Disease Modifying Anti-Rheumatic Drugs (cDMARD) plus anti-tumour necrosis factor (anti-TNF) from baseline to 6 months compared with cDMARDs, as…
- Trial name
- HUMAN (NCT03264703)
- Where
- 15 sites in South Korea
- Volunteers
- 212 people
- Sponsor
- Eisai Korea Inc.
Erythema
Multiday Beach Study
This is a randomized, double-blinded, single-center, split body and split face, multiple natural sunlight exposure evaluation of two marketed sunscreens under actual use conditions in healthy volunteers.
- Trial name
- NCT03041064
- Testing
- 50/100, 100/50
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis
Phase III Clinical Trial of NPB-01 in Patients With Stevens-Johnson Syndrome/ Toxic Epidermal Necrolysis Unresponsive to Corticosteroids.
Patients diagnosed with Stevens-Johnson syndrome and Toxic Epidermal Necrolysis were confirmed based on the investigators national diagnostic criteria.
- Trial name
- NCT01696500
- Testing
- Intravenous immunoglobulin
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Nihon Pharmaceutical Co., Ltd
Erythema, Edema
A Clinical Study to Evaluate the Safety of a Personal Lubricant in Healthy Female Subjects
To evaluate the safety of a personal lubricant when used at least four times weekly for two weeks (including at least twice weekly during sexual intercourse for subjects with monogamous male partners), in a population consisting…
- Trial name
- NCT02737592
- Testing
- Trojan "Simply Pleasure" Personal Lubricant
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Erythema
Skin Irritation Potential of MOB015B in Healthy Subjects Using a Cumulative Irritant Patch Test Design
A 21-Day, Randomized, Controlled Study to Evaluate the Skin Irritation Potential of MOB015B in Healthy Subjects Using a Cumulative Irritant Patch Test Design To evaluate the irritation potential of MOB015B on normal skin.
- Trial name
- CIPT (NCT06369675)
- Testing
- MOB015B, 0.2% SLS, 0.9% Saline
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Moberg Pharma AB
Transepidermal Water Loss, Erythema
Skin Protectant Properties of Omeza Collagen Matrix on Damaged Skin
Single-blind within subject comparison study conducted to investigate the skin protectant properties of Omeza Collagen Matrix on damaged skin
- Trial name
- NCT04512274
- Testing
- Test Article
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Omeza, LLC
Erythema, Sensitisation
50 Human Subject Repeat Insult Patch Test
Consumer products or raw materials designed for consistent reapplication to areas of the skin may, under proper conditions, prove to be contact sensitizers or irritants in certain individuals.
- Trial name
- HRIPT (NCT04498676)
- Testing
- CB-0002B
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CAGE Bio Inc.
Allergic Conjunctivitis, Allergic Rhinitis
Therapeutic Effect of Tacrosolv in Patients With Allergic Rhinoconjunctivitis
Allergic conjunctivitis is one of the most common comorbidities of allergic diseases, especially of allergic rhinitis. Rhinoconjunctivitis is an allergic condition of the nasal mucosa and the eyes.
- Trial name
- NCT04532710
- Testing
- Eye Drops, Solution in Single-Dose Container
- Where
- Austria
- Volunteers
- 64 people
- Sponsor
- Marinomed Biotech AG
Allergic Conjunctivitis
A Single-Center, Randomized, Double-Masked, Placebo and Active Controlled, Dose-Ranging Evaluation of the Duration of Action of Brimonidine Tartrate Ophthalmic Solution in the Control of Ocular Redness Induced by Conjunctival Allergen Challenge (CAC)
The purpose of this study is to evaluate the safety, efficacy, and dose response of brimonidine tartrate ophthalmic solution as compared to placebo in the prevention of allergen-induced conjunctival redness using a conjunctival…
- Trial name
- NCT01275105
- Testing
- Vehicle, Brimonidine Tartrate 0.01%, Brimonidine Tartrate 0.025%
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Eye Therapies, LLC
Ocular Hyperemia
An Investigation of FID 123472 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness in Adults
The purpose of this study is to evaluate the efficacy and safety of an investigational ophthalmic solution in adults with ocular redness caused by minor eye irritations.
- Trial name
- NCT07578363
- Testing
- Apraclonidine Ophthalmic Solution, 0.125% Unit Dose Preservative Free, Vehicle
- Where
- 5 sites in United States
- Volunteers
- 178 people
- Sponsor
- Alcon Research
Rosacea
A Phase II, Randomized Study of ACZONE™ (Dapsone) Gel, 5% for Papulopustular Rosacea.
The purpose of this study is to evaluate the safety and effectiveness of ACZONE™ gel compared to placebo (inactive substance), MetroGel® and a combination of ACZONE™ gel and MetroGel® for the treatment of rosacea.
- Trial name
- NCT00249782
- Testing
- Vehicle control, 2x/day, ACZONE (dapsone) Gel, 5%, 2x/day, ACZONE (dapsone) Gel, 5%, 1x/day
- Where
- 26 sites in United States
- Volunteers
- 400 people
- Sponsor
- Allergan
Lyme Disease
ImmuneSense Lyme Study
ImmuneSense Lyme is a study, which is designed to better understand the immune response to Lyme disease. This is critically important because the immune system may be able to tell us important information about how our own bodies…
- Trial name
- NCT04422314
- Testing
- T-Detect Lyme
- Where
- 34 sites in United States
- Volunteers
- 893 people
- Sponsor
- Adaptive Biotechnologies
Mild Gingival Recession, Periodontal Inflammation
Efficacy and Safety of HA35 Gel for Mild Gingival Recession and Periodontal Inflammation
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of topical 10% high-concentration 35 kDa hyaluronan (HA35) gel in subjects with mild gingival recession and chronic…
- Conditions
- Mild Gingival Recession, Periodontal Inflammation, Chronic Gingival Pain, Gingival Redness and Swelling
- Trial name
- HA35-PERI (NCT07577258)
- Testing
- 10% High-Concentration 35 kDa Hyaluronan (HA35) Gingival Topical Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Ocular Hyperemia
Efficacy and Safety of FID 123472 Ophthalmic Solution for Ocular Redness in Adults
The purpose of this study is to evaluate the efficacy and safety of an investigational ophthalmic solution in adults with ocular redness due to minor eye irritations.
- Trial name
- NCT07531043
- Testing
- Apraclonidine Ophthalmic Solution, 0.125% Unit Dose Preservative Free, Vehicle
- Where
- 9 sites in United States
- Volunteers
- 230 people
- Sponsor
- Alcon Research
Pigmentation, Redness
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under UV Day Light Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on UV Day Light induced pigmentation in healthy volunteers
- Trial name
- NCT04866797
- Testing
- cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal