Clinical trials: Erythema Migrans
Allergic Rhinitis, Geographic Tongue
The Relationship Between Allergic Rhinitis and Geographic Tongue
Allergic rhinitis is a complex chronic inflammatory disease, it always presents with nasal obstruction, nasal itching, sneezing and runny nose. Whether in adults or children, rhinitis is a complex disease.
- Trial name
- AR-GT (NCT01454492)
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Erythema Migrans
Patient's Pretreatment Expectations About Post-Lyme Symptoms
The investigators will focus on pretreatment expectations of patients with early Lyme disease manifested as erythema migrans with the aim of assessing the association between pretreatment expectations quantified with a…
- Trial name
- NCT03462329
- Testing
- Antibiotics (preferentially oral doxycycline 100 mg bid)
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Erythema Chronicum Migrans
Duration of Antibiotic Treatment of Erythema Migrans
The purpose of this study is to compare the efficacy of 15-day versus 10-day doxycycline treatment in patients with erythema migrans.
- Trial name
- NCT00910715
- Testing
- doxycycline
- Where
- Slovenia
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Erythema Chronicum Migrans
Duration of Doxycycline Treatment in MEM Patients
The purpose of this study is to compare the efficacy of 7-day versus 14-day doxycycline treatment in patients with multiple erythema migrans.
- Trial name
- NCT03337932
- Testing
- Doxycycline 100 milligram Oral Tablet bid, 7 days, Doxycycline 100 milligram Oral Tablet bid, 14 days, Controls without a history of lyme disease.
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Patients With Different Manifestations of Lyme Borreliosis, Persons With Nonspecific Symptoms and Positive Borrelia Antibodies in Serum
Anti-phospolipid Antibodies in Lyme Borreliosis
Background Lyme borreliosis, caused by Borrelia burgdorferi sensu lato is transmitted to humans through the bite of an infected Ixodes tick. B.
- Conditions
- Patients With Different Manifestations of Lyme Borreliosis, Persons With Nonspecific Symptoms and Positive Borrelia Antibodies in Serum, Blood Donors
- Trial name
- NCT06929546
- Testing
- Anti-phospholipid antibodies
- Where
- Slovenia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Erythema Migrans, Post-Lyme Disease Symptoms
Comparison of Doxycycline and Cefuroxime Axetil for Treatment of Erythema Migrans: Clinical and Microbiological Outcome
Background: While doxycycline is a standard antibiotic for treatment of erythema migrans in Europe as well as in the USA, the effectiveness of cefuroxime axetil in the treatment of adult patients with erythema migrans has been…
- Trial name
- NCT01518192
- Testing
- doxycycline, cefuroxime axetil
- Where
- 2 sites in Slovenia
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Erythema Migrans Lesions, Erythema Migrans
Analysis of Lyme Disease Lesions
This study will analyze cells from erythema migrans lesions, the "bull's eye" rash of Lyme disease. Little is known about what happens in the skin when it is infected with Borrelia burgdorferi, the bacteria that cause Lyme…
- Trial name
- NCT00132327
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Erythema Chronicum Migrans
Duration of Doxycycline Treatment in EM Patients
The purpose of this study is to compare the efficacy of 7-day versus 14-day doxycycline treatment in patients with erythema migrans.
- Trial name
- NCT03153267
- Testing
- Doxycycline 100 MG Oral Tablet bid, 7 days, Doxycycline 100 MG Oral Tablet bid, 14 days, Controls without a history of lyme disease.
- Where
- Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Lyme Disease, Erythema Migrans
Erythema Migrans in Elderly
The investigators will focus on elderly patients with early Lyme borreliosis with the aim of assessing clinical course, serological response and treatment outcome of the disease as compared to younger adults.
- Conditions
- Lyme Disease, Erythema Migrans, Elderly Infection
- Trial name
- NCT03371563
- Testing
- Antibiotics, no intervention
- Volunteers
- 1,220 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Erythema Migrans
Different Amoxicillin Treatment Regimens in Erythema Migrans Patients
The purpose of this study is to compare the efficacy of different amoxicilline treatment regimens in patients with erythema migrans.
- Trial name
- NCT03966014
- Testing
- EM-amoxicillin 3 x 10 days, EM-amoxicillin 3 x 14 days, Controls
- Where
- 2 sites in Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Lyme Disease, Pediatric Infectious Disease
Next Generation Sequencing Detection of Lyme Disease
Next Generation Sequencing is capable of sequencing millions of small strands of DNA from a single blood sample, potentially improving its sensitivity compared to PCR testing, which only detects predetermined larger strands of…
- Conditions
- Lyme Disease, Pediatric Infectious Disease, Erythema Migrans, Lyme Arthritis
- Trial name
- NCT03505879
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Multiple Erythema Migrans
Antibiotic Treatment of Multiple Erythema Migrans
The purpose of this study is to compare the efficacy and safety of 15-day ceftriaxone versus 15-day doxycycline treatment in patients with multiple erythema migrans.
- Trial name
- NCT01163994
- Testing
- ceftriaxone, doxycycline, erythema migrans patients treated with doxycycline
- Where
- Slovenia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Tongue; Anomaly
Prevalence of Tongue Anomalies in Egyptian Children
The purpose of the study is to determine the prevalence of tongue anomalies in a group of Egyptian children and to relate the presence of malocclusion in cases of macroglossia, tongue tie and microglossia.
- Trial name
- NCT05779618
- Testing
- no intervention
- Where
- 2 sites in Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Cairo University
Erythema Chronicum Migrans
Comparison of Doxycycline and Cefuroxime Axetil in Erythema Migrans
A European, prospective clinical trial in which doxycycline and cefuroxime axetil were compared in the treatment of adult patients with erythema migrans included a control group to address this question.
- Trial name
- NCT03584919
- Testing
- doxycycline, Cefuroxime Axetil 500Mg Tab, control subjects
- Volunteers
- 509 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Lyme Borreliosis
Doxycycline in Therapy of Erythema Migrans
The investigators will compare the outcome of three groups of erythema migrans patients treated with doxycycline: a group without any accompanying symptoms, with mild symptoms and with severe symptoms that require lumbar puncture.
- Trial name
- NCT01475708
- Testing
- Doxycycline
- Where
- Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana