Clinical trials: Erythropoietin
Chronic Renal Anemia
A Study to Assess All-Cause Mortality and Cardiovascular Morbidity in Participants With Chronic Kidney Disease (CKD) on Dialysis and Those Not on Renal Replacement Therapy Receiving Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) or Reference Erythropoietin Stimulating Agents (ESAs)
This 2 arm safety study will compare the outcome with respect to a composite endpoint of all-cause mortality and non-fatal cardiovascular events (myocardial infarction, stroke) in CKD participants either on dialysis or not…
- Trial name
- NCT00773513
- Testing
- Darbepoetin Alfa, Epoetin Alfa, Epoetin Beta
- Where
- 196 sites in Argentina, Australia and 25 more
- Volunteers
- 2,825 people
- Sponsor
- Hoffmann-La Roche
Anemia, Chronic Kidney Disease
20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia
The purpose of this study is to evaluate the hemoglobin response (efficacy), safety, and tolerability of orally administered AKB-6548 in participants with Chronic Kidney Disease (pre-dialysis) with anemia with dosing for 20 weeks.
- Trial name
- NCT01906489
- Testing
- AKB-6548
- Where
- 47 sites in United States
- Volunteers
- 210 people
- Sponsor
- Akebia Therapeutics
Anemia of End Stage Renal Disease
TARGTEPO Treatment for Anemia in End Stage Renal Disease (ESRD) Patients Undergoing Peritoneal Dialysis (PD)
The objectives of this study are to assess safety and to evaluate the biologic activity of TARGTEPO treatment in Peritoneal Dialysis patients
- Trial name
- NCT02378662
- Testing
- MDGN201 TARGTEPO
- Where
- 2 sites in Israel
- Volunteers
- 2 people
- Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company
Perinatal Asphyxia
Neuroprotective Role of Erythropoietin in Perinatal Asphyxia
Whether Erythropoietin improves the neurological outcomes of neonates with perinatal asphyxia.
- Trial name
- NCT02002039
- Testing
- Erythropoietin
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Sheri Kashmir Institute of Medical Sciences
Non-Small-Cell Lung Carcinoma, Lung Cancer
Epoetin Alfa in Advanced Non-Small Cell Lung Cancer (EPO-CAN-20)
The general objective of this study is to improve the Quality of Life (QoL) of selected patients with advanced carcinoma of the lung.
- Conditions
- Non-Small-Cell Lung Carcinoma, Lung Cancer, Anemia
- Trial name
- NCT00310232
- Testing
- Epoetin Alfa
- Where
- 15 sites in Canada
- Volunteers
- 70 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Trauma
Early Administration of Recombinant Erythropoietin (RHEPO) in Transfusion Savings in Trauma Patients
The objective of our study is to demonstrate the interest of early administration of recombinant erythropoietin in trauma patients
- Trial name
- EPREX (NCT03867071)
- Testing
- recombinant erythropoietin injection
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Epoetin Alfa in Treating Fatigue in Patients With Advanced Solid Tumors Who Are Not Receiving Chemotherapy
RATIONALE: Epoetin alfa may help improve energy levels and quality of life in patients who have advanced solid tumors. PURPOSE: Randomized clinical trial to study the effectiveness of epoetin alfa in treating fatigue in patients…
- Trial name
- NCT00052221
- Testing
- Epoetin alfa
- Sponsor
- M.D. Anderson Cancer Center
Kidney Failure, Chronic, Anemia
Audit of the Effect of Changing From IV to SC Administration of ESA's in Haemodialysis Patients
The purpose of this study is to audit the effects of changing all hemodialysis patients from intravenous to subcutaneous administration of ESA's, to ensure that a cost-saving is achieved and that this does not occur at the…
- Trial name
- NCT00382044
- Testing
- Eprex; Neorecormon; Aranesp
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- Sir Charles Gairdner Hospital
Cyanotic Congenital Heart Disease, Anemia
Erythropoietin to Prevent Unnecessary Transfusions In Patients With Cyanotic CHD - A Prospective Control Trial
Cyanotic congenital cardiac patients require higher hemoglobin concentrations (red blood cell levels) for optimal oxygen delivery to the body.
- Conditions
- Cyanotic Congenital Heart Disease, Anemia, Cyanosis, Congenital Heart Disease
- Trial name
- NCT02564796
- Testing
- Epoetin Alfa and Iron, Iron
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
Anemia, Lymphoma
Erythropoietin in the Treatment of Anemia After Autologous Hematopoietic Stem Cell Transplantation
This is an randomized trial to evaluate the potential benefit of erythropoietin in the treatment of anemia in patients with lymphoma after autologous hematopoietic stem cell transplantation.
- Conditions
- Anemia, Lymphoma, Hematopoietic Stem Cell Transplantation
- Trial name
- NCT03010579
- Testing
- erythropoietin, iron supplementation
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University
Acute Myocardial Infarction
The Effect of Erythropoietin at the Time of Reperfusion in Acute Myocardial Infarction
The purpose of this study is to investigate the effect of intravenous human recombinant erythropoietin on the reperfusion injury at primary percutaneous coronary intervention in patients with acute myocardial infarction.
- Trial name
- NCT00882466
- Testing
- human recombinant erythropoietin
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Seoul National University Bundang Hospital
Cardiac Surgery, Transfusion
Transfusion Savings in Heart Surgery: Impact of Individual Strategy by Erythropoietin and Metabolic Adjustment (ScvO2)
Preoperative anemia, bleeding and transfusions have been recognized as a "Deadly triad" in cardiac surgery associated with an increased morbidity,mortality, and costs related.
- Conditions
- Cardiac Surgery, Transfusion, Perioperative Anemia
- Trial name
- BLOOCOST (NCT04141631)
- Testing
- EPO (600UI/Kg, sub-cutaneous) and Ferric Carboxymaltose (FCM) (20 mg/kg in 250 mL of saline solution 0.9% over 15 min)
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Montpellier
Neonatal Anemia
Optimized Erythropoietin (EPO) Treatment
Neonatal anemia is the most commonly encountered hematologic problem among all neonates cared for in the neonatal intensive care unit (NICU).
- Trial name
- OETNA (NCT02075970)
- Testing
- Epoetin Alpha
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Iowa
Anemia, Chronic Kidney Disease
Efficacy and Safety of Peginesatide (AF37702) in the Treatment of Anemia in Participants With Chronic Kidney Disease
The purpose of this study is to evaluate the ability of peginesatide (AF37702) to increase and maintain increased hemoglobin levels in participants with chronic kidney disease (CKD) (either not on dialysis, receiving regular…
- Conditions
- Anemia, Chronic Kidney Disease, Chronic Renal Failure, Pure Red Cell Aplasia
- Trial name
- NCT00314795
- Testing
- Peginesatide
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 22 people
- Sponsor
- Takeda
Myelodysplastic Syndromes
Azacitidine and Erythropoietin Versus Azacitidine Alone for Patients With Low-Risk Myelodysplastic Syndromes
This trial is designed to explore a modified dose and schedule of azacitidine in order to more effectively address the needs of patients with low-risk myelodysplastic syndromes (MDS), i.e., to alter the natural history of the…
- Trial name
- NCT00379912
- Testing
- Azacitidine, Erythropoietin, Azacitidine (Monotherapy)
- Where
- 9 sites in United States
- Volunteers
- 15 people
- Sponsor
- Larry Cripe, MD
Hip Fractures
Efficacy of Ferric Carboxymaltose With or Without EPO Reducing Red-cell Transfusion Packs in Hip Fracture Perioperative Period
In order to evaluate the efficacy of ferric carboxymaltose + erythropoietin versus ferric carboxymaltose versus placebo in reducing the percentage of patients who receive red-cell transfusion in the perioperative period of hip…
- Trial name
- PAHFRAC (NCT01154491)
- Testing
- Ferric carboxymaltose, Erythropoietin
- Where
- 14 sites in Spain
- Volunteers
- 303 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Anemia, Iron Deficiency Anemia
The Effect of Combined Iron Protocols on Perioperative Allogeneic Transfusion
The goal of this clinical trial is to learn if a combined iron supplementation regimen can reduce the need for blood transfusions in adults with iron-deficiency anemia undergoing major elective cardiac surgery.
- Conditions
- Anemia, Iron Deficiency Anemia, Perioperative, Transfusion
- Trial name
- CIPAT (NCT06012760)
- Testing
- Iron sucrose, Human Erythropoietin Injection, Vitamin C, Standard Medical Care
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anemia, Kidney Disease, Chronic
An Observational Study of Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) as Maintenance Treatment in Patients With Chronic Renal Anemia on Haemodialysis
This prospective observational study will evaluate the safety and efficacy of Mircera (methoxy polyethylene glycol-epoetin beta) in patients with chronic renal anemia on haemodialysis in maintenance ESA treatment.
- Trial name
- NCT01422824
- Where
- 6 sites in North Macedonia
- Volunteers
- 185 people
- Sponsor
- Hoffmann-La Roche
MDS
Prognostic Value of Serum Erythropoietin Level,Ferritin Level and Fibrinogen in Adult Low Risk MDS
1. assessment of the penefit of erythropoietin administration in decreasing the frequency of blood transfusion in adult low risk MDS 2.
- Trial name
- NCT04573686
- Testing
- Erythropoietin
- Volunteers
- 50 people
- Sponsor
- Assiut University
Alveolar Bone Loss
Evaluation of Erythropoietin on Alveolar Ridge Preservation
regenerative materials would help in decreasing post-extraction resorption in sites indicated for placement of a conventional bridge or prosthetically driven implant.
- Trial name
- NCT06513039
- Testing
- Erythropoietin carried on chitosan carrier, chitosan carrier
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ain Shams University