Clinical trials: Essential (Primary) Hypertension
Essential Hypertension, Primary Hypercholesterolemia
To Evaluate the Renal Protective Effects and Safety of 'Fimasartan and Atorvastatin' or 'Fimasartan, Atorvastatin and Ezetimibe'.
This prospective study aims to observe changes in renal function and related parameters in patients with essential hypertension and primary hypercholesterolemia receiving either the combination of fimasartan and atorvastatin or…
- Trial name
- NCT07685054
- Volunteers
- 12,700 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension,Essential
Engaging Home-monitored Assessment to Navigate Clinical Decision-making
This study is testing a new app called ENHANCe, which is designed to help family doctors manage patients with high blood pressure using readings taken at home.
- Trial name
- ENHANCe (NCT07399912)
- Testing
- ENHANCe app, Teaching and training, Usual care
- Where
- Singapore
- Volunteers
- 116 people
- Sponsor
- SingHealth Polyclinics
Primary Hypertension, Secondary Hypertension
Dose Titration of Lisinopril in Children Aged 1 to 18 Years With Primary or Secondary Hypertension
This open label 4 month study will evaluate efficacy (blood pressure lowering effects) and safety of lisinopril in children 1-18y whose parents grant permission to participate.
- Trial name
- Lisi-ped (NCT02184858)
- Testing
- lisinopril, ACE-inhibitor
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- University Ghent
Hypertension,Essential, White Coat Hypertension
Implementing Hypertension Screening Guidelines in Primary Care
The goal of this study is to use a cluster-randomized design (1:1 ratio) among 8 primary care clinics affiliated with New York-Presbyterian Hospital to test the effectiveness of a theory-informed multifaceted implementation…
- Trial name
- EMBRACE (NCT03480217)
- Testing
- Multifaceted Implementation Strategy, Usual care
- Where
- 2 sites in United States
- Volunteers
- 1,186 people
- Sponsor
- Columbia University
Essential Hypertension, Primary Hypercholesterolemia
A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1017-1" and Co-administration of "BR1017-1A" and "BR1017-1B"
The objective of this clinical study is to evaluate the pharmacokinetics and the safety after administration of "BR1017-1" and co-administration of "BR1017-1A" and "BR1017-1B" in healthy volunteers
- Trial name
- NCT06184269
- Testing
- BR1017-1, BR1017-1A, BR1017-1B
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Essential Hypertension, Primary Hypercholesterolemia
A Study to Evaluate the Efficacy and Safety of Co-administrated BR1018B and BR1018C
The purpose of this clinical trial is to evaluate the efficacy and safety of co-administrated BR1018B and BR1018C in patients with essential hypertension and primary hypercholesterolemia
- Trial name
- NCT06165250
- Testing
- BR1018A, BR1018A-1, BR1018B
- Where
- 2 sites in South Korea
- Volunteers
- 151 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Primary Hypertension
The Effectiveness of "MaRiTensi" in Increasing Self-Care and Blood Pressure Control: Randomized Controlled Trial
This study aims to know the effectiveness of "MaRiTensi" in improving knowledge, motivation, efficacy, self-care and blood pressure control for hypertension patients.
- Trial name
- "MaRiTensi" (NCT06049862)
- Testing
- MaRiTensi App
- Where
- 3 sites in Indonesia
- Volunteers
- 99 people
- Sponsor
- Chatarina Setya Widyastuti
Pediatric Hypertension, Primary Hypertension
Endothelial Extracellular Vesicles as Biomarkers of Endothelial Activation in Children With Newly Diagnosed Hypertension
Childhood hypertension is associated with early endothelial dysfunction and an increased risk of future cardiovascular disease. Endothelial extracellular vesicles (EEVs) have emerged as promising biomarkers of endothelial…
- Conditions
- Pediatric Hypertension, Primary Hypertension, Endothelial Dysfunction
- Trial name
- HYPER-endoEV-c (NCT07728643)
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Healthy Individuals (Controls), PRIMARY HYPERTENSION PATIENT
The Effect of Motivational Interviewing on Knowledge, Self-Efficacy, and Treatment Adherence in Patients With Primary Hypertension Living in Semi-Rural Areas
This study is a single-center, single-blind, parallel-group randomized controlled trial designed to examine the impact of a Health Belief Model (HBM)-based motivational interviewing (MI) intervention on knowledge level…
- Trial name
- NCT07307924
- Testing
- Motivasyonel görüşme
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Hypertension
CKD-828 (40/5mg) Pharmacokinetic Study
The purpose of this study is to evaluate the pharmacokinetic characteristics of CKD-828 (Fixed Dose Combination Tablet; Telmisartan and S-Amlodipine) in healthy volunteer.
- Trial name
- NCT01340131
- Testing
- CKD-828, Combination Therapy
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Essential Hypertension
To Evaluate the Safety and Efficacy of a Single-Use IVUS Ablation for Primary Hypertension
This is a prospective, multicenter, blinded, randomized controlled clinical trial designed to evaluate the safety and efficacy of a single-use intravascular ultrasound ablation catheter and ultrasound ablation system in the…
- Trial name
- NCT07051811
- Testing
- Intravascular Ultrasound Ablation Therapy, Renal Artery Angiography
- Where
- 18 sites in China
- Volunteers
- 213 people
- Sponsor
- Lepu Medical Technology (Beijing) Co., Ltd.
Primary Hypertension
Efficacy Observational Study of Candesartan Cilexetil on Hypertensive Patients
The purpose of this study is to observe treatment with candesartan cilexetil 16mg for 8 weeks, in uncontrolled hypertensive patients, in improvement of achieving of treatment goals and impact on blood pressure level in patients…
- Trial name
- NCT00573742
- Testing
- Candesartan Cilexeotil 16mg
- Where
- 16 sites in Romania
- Volunteers
- 1,940 people
- Sponsor
- AstraZeneca
Hypertension
CKD-828 Primary Hypertension Trial(Dose-selection)
The aim of this trial is to determine the best dose combination of S-Amlodipine and Telmisartan as compared to monotherapy by assessing the blood pressure lowering effects of a once daily regimen of various combinations of…
- Trial name
- NCT01128322
- Testing
- S-Amlodipine, Telmisartan, S-Amlodipine, Telmisartan
- Where
- 26 sites in South Korea
- Volunteers
- 430 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Hypertension
CKD-828(80/2.5mg) Pharmacokinetic Study
The purpose of this study is to evaluate the pharmacokinetic characteristics of CKD-828(Fixed Dose Combination Tablet; Telmisartan and S-Amlodipine) in healthy volunteer.
- Trial name
- NCT01246193
- Testing
- CKD-828(FDC), Combination Therapy
- Where
- South Korea
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Myeloproliferative Neoplasms (MPN), Polycythemia Vera (PV)
Screening for Asymptomatic Portal Vein Thrombosis and Portal Hypertension in Patients With Philadelphia Negative Myeloproliferative Neoplasms
This study involves screening for portal vein thrombosis and portal hypertension in patients with Philadelphia negative myeloproliferative neoplasms (MPNs).
- Conditions
- Myeloproliferative Neoplasms (MPN), Polycythemia Vera (PV), Essential Thrombocythemia (ET), Myelofibrosis (MF)
- Trial name
- NCT01816256
- Testing
- Upper gastrointestinal endoscopy and Doppler ultrasound
- Where
- 2 sites in Canada
- Volunteers
- 102 people
- Sponsor
- University Health Network, Toronto
Essential Hypertension, Primary Hypertension
Assessment of Efficacy and Safety of Amicomed®, for the Management of Essential Hypertension
This is a multicenter, randomized, single-blind, parallel-group study to evaluate the efficacy and safety of Amicomed® compared with Usual Care (UC) over a 24-week treatment period in subjects with essential hypertension (mean…
- Trial name
- NCT06091176
- Testing
- Amicomed®, Usual Care
- Volunteers
- 316 people
- Sponsor
- Newel Health SRL
Hypercholesterolemia, Hypertension
Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan
The purpose of this study is to evaluate the efficacy and safety of co-administrated Rosuvastatin/Ezetimibe and Telmisartan in patients with primary hypercholesterolemia and essential hypertension.
- Trial name
- NCT03872232
- Testing
- Ezetimibe/Rosuvastatin, Telmisartan
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Addpharma Inc.
Primary Hypertension, Grade 2
Aerobic Exercise vs Physiological Ischemic Training in Stage 2 Hypertension
This study aims to compare the effects of aerobic exercise (AE) and physiological ischemic training (PIT) on inflammatory and angiogenesis biomarkers (VEGF, IL-6, IL-10), cardiorespiratory fitness, muscle strength, and quality of…
- Trial name
- NCT07375407
- Testing
- Aerobic Exercise (AE), Physiological Ischemic Training (PIT)
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Padjadjaran
Essential (Primary) Hypertension
Smartphone-Guided Paced Breathing and Aerobic Exercise for Essential Hypertension
Hypertension is a major risk factor for cardiovascular disease and is associated with reduced functional capacity and impaired quality of life.
- Trial name
- SPB-HTN (NCT07717996)
- Testing
- Smartphone-Guided Paced Breathing, Aerobic Exercise, Smartphone-Guided Paced Breathing + Aerobic Exercise
- Volunteers
- 75 people
- Sponsor
- Cairo University
Hyperaldosteronism, Hypertension
Water and Electrolytes Content in HYpertension (WHYSKI) in the SKIn
WHYSKI is a prospective within-patient observational clinical study designed to test the hypothesis that alterations of Na+, K+, water, and the lympho-angiogenetic transcription factor Tonicity Enhancing Binding Protein (TonEBP)…
- Conditions
- Hyperaldosteronism, Hypertension, Aldosterone-producing Adenoma, Aldosteronism
- Trial name
- WHYSKI (NCT06090617)
- Testing
- Skin Biopsy, Video-laparoscopic adrenalectomy
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova