Clinical trials: Estradiol
All IVF Patients
The Impact of In-Vitro Fertilization (IVF) ON Vitamin D
The main objective of this study is to determine what is the vitamin D status in Israeli women undergo ART. We want to evaluate the influence of hyper Vitamin D level and low vitamin D level on IVF -ICSI cycles.
- Trial name
- NCT01945658
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Pregnancy Prevention
A Study to Evaluate the Effect of a Contraceptive Vaginal Ring LSP- 5415 on Ovarian Function in Healthy Adult Females
The primary objective of this study is to evaluate the inhibition of ovulation in Cohort #1 (Body Mass Index of ≥ 18 kg/m2 to ≤ 30 kg/m2) after contraceptive vaginal ring LSP-5415 application for 3 treatment cycles.
- Trial name
- NCT05360550
- Testing
- LSP-5415
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lupin Research Inc
Alcohol Use, Unspecified
Estradiol Effects on Alcohol Across the Menstrual Cycle
This study will provide the first rigorous integrative test of the hypothesis that rapid rises in estradiol (a female hormone) increase the rewarding and disinhibiting effects of alcohol and that such increased sensitivity…
- Trial name
- NCT04595682
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mark Fillmore
Frozen Embryo Transfer
The Association Between Serum E2 and P on the Day of FET and the Pregnancy Outcome
The outcomes of frozen embryo transfer (FET) have substantially improved over the last decade, due to the improvements in the cryopreservation process, Artificial endometrial preparation is typically accomplished by the…
- Trial name
- FET (NCT04114500)
- Testing
- serum estradiol and progesterone
- Where
- Bahrain
- Volunteers
- 402 people
- Sponsor
- Al Baraka Fertility Hospital
Acne Vulgaris
Evaluate Safety and Efficacy of an Oral Contraceptive (OC) Preparation Versus Placebo for 6 Treatment Cycles in Women With Moderate Acne
The objectives of this study were to evaluate the efficacy and safety of drospirenone 3 mg/ethinyl estradiol 0.02 mg (DRSP/EE) in comparison with placebo in female subjects with moderate acne vulgaris during 6 treatment cycles
- Trial name
- NCT00656981
- Testing
- YAZ (DRSP 3 mg/EE 0.02 mg, BAY86-5300)
- Where
- 22 sites in United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Bayer
Infertility, Female, Reproductive Sterility
Evaluation of Salivary ELISA for Hormone Monitoring in IVF Patients
In assisted reproductive treatment (ART), it is necessary to follow closely the stimulation cycles of patients undergoing these treatments in order to monitor the number and size of developing follicles.
- Trial name
- SALIVA_MINT (NCT05184777)
- Testing
- Determination of progesterone and oestradiol
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Osteopenia
3-year Study of Menostar Versus Evista to Prevent Osteoporosis in Post-menopausal Women
The aim of this trial is to investigate whether the Menostar patch is as safe and effective in the prevention of bone loss in postmenopausal women as raloxifen, a drug already registered for prevention and treatment of…
- Trial name
- NCT00310531
- Testing
- Menostar (Estradiol, BAY86-5435), Raloxifene
- Volunteers
- 500 people
- Sponsor
- Bayer
Infertility
Effectiveness of Estradiol Valerate Pretreatment in Antagonist Protocol for Poor Ovarian Response Patient
The purpose of study is to assess the efficacy of add-on estrogen pretreatment in GnRH antagonist protocol on oocyte retrieval as compared with GnRH antagonist protocol for patients with poor ovarian response Add-on estrogen…
- Trial name
- NCT03300518
- Testing
- Follitropin Beta;MSD, Ganirelix, hCG
- Where
- China
- Volunteers
- 552 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Healthy
A Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl Estradiol
The purpose of this study is to determine the effect of JNJ-55308942: 1) high dose at steady state on the single dose pharmacokinetics of a cocktail containing selective probes of cytochrome P450 (CYP) enzymes (CYP3A, CYP2D6 and…
- Trial name
- NCT03547024
- Testing
- JNJ-55308942 High Dose, JNJ-55308942 Low Dose, Levonorgestrel/Ethinyl Estradiol Fixed Dose combination (FDC)
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Janssen-Cilag International NV
Fertility
Effect of GnRH Antagonist vs Agonist Long on IVF Outcome, Peak Estradiol Level,and Duration of Stimulation
The purpose of this study is to determine if utilizing GnRH antagonists versus agonist long protocol during controlled ovarian stimulation (COH) with human-derived gonadotropins for assisted reproduction affects IVF outcome, peak…
- Trial name
- NCT01669291
- Testing
- Bravelle and Menopur, Agonist, Antagonist
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
HIV Infection, Vaginal Atrophy
Accelerated Genital Tract Aging in HIV: Estradiol Clinical Trial
During menopause, there is a decrease in a hormone estrogen, which leads to aging of the vagina. Vaginal aging includes changes in the type and amount of healthy bacteria in the vagina, inflammation and a breakdown of natural…
- Conditions
- HIV Infection, Vaginal Atrophy, Menopause, Menopause Related Conditions
- Trial name
- NCT04079218
- Testing
- Estradiol Vaginal Insert
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kerry Murphy
Hirsutism, Androgenetic Alopecia
DUS on the Prescribing Indications for CPA/EE in 5 European Countries
This study was designed to compile the reasons and specific indications for the prescription of Cyproterone Acetate combined with Ethinyl Estradiol by Health Care Providers.
- Conditions
- Hirsutism, Androgenetic Alopecia, Severe Anemia, Seborrhea
- Trial name
- NCT02494297
- Where
- Germany
- Volunteers
- 1,597 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Primary Ovarian Insufficiency, Menopause, Premature
Oral Contraceptives as Infertility Treatments for Premature Ovarian Failure
Premature ovarian insufficiency (POI) is a life-changing condition that affects women in their reproductive age. There is a lack of reports which focus on how to improve the reproductive outcome of these women who wish to…
- Trial name
- NCT02757469
- Testing
- Drospirenone and ethinyl estradiol combination (Yasmin)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Navy General Hospital, Beijing
Reproductive Behavior
Endometrial Preparation in Frozen Embryo Transfer Cycles
Comparison of protocols for frozen embryo transfer (ET): One protocol using Estrogen supplements and the second protocol using Letrozole
- Trial name
- NCT03540979
- Testing
- endometrial preparation for frozen blastocyst transfer, Letrozole, Ovidrel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Estrogen, Menopause
Patient Adherence to Premarin Versus Vagifem Therapy After Female Pelvic Reconstructive Surgery
PURPOSE: To evaluate patient adherence to cream versus tablet based local estrogen therapy by randomizing treatment modalities to determine differences in adherence to either form.
- Conditions
- Estrogen, Menopause, Pelvic Floor Disorders, Surgery
- Trial name
- NCT02860897
- Testing
- Premarin, Vagifem
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Premenstrual Syndrome, Depression
Combined Hormone Replacement in Menstrually-Related Mood Disorders
This study investigates the effects on symptoms of combined treatment with estrogen and progesterone in women with severe premenstrual syndrome (PMDD).
- Trial name
- NCT00005011
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Institute of Mental Health (NIMH)
Contraception
An Open-label Study to Evaluate Contraceptive Efficacy and Safety of the Transdermal Contraceptive System of Norelgestromine and Ethinyl Estradiol
The purpose of this study is to evaluate the contraceptive efficacy, safety, cycle control, compliance, and subject satisfaction of the transdermal contraceptive system, norelgestromine and ethinyl estradiol (NLGM / EE).
- Trial name
- NCT00307632
- Testing
- Norelgestromine (NLGM)/ethinyl estradiol (EE)
- Where
- 12 sites in Brazil, Mexico
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Janssen-Cilag Farmaceutica Ltda.
Menopause, Postmenopausal Vaginal Atrophy
Comparison of Two Vaginal Tablets, Produced at Different Sites, in Postmenopausal Women With Atrophic Vaginitis
This trial is conducted in Europe. The aim of this trial is to compare the absorption of estradiol after a single dose of two 25 mcg estradiol vaginal tablets, produced at two different production sites, in postmenopausal women…
- Trial name
- NCT01085877
- Testing
- estradiol, 25 mcg
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Novo Nordisk A/S
Healthy
A Study of Lanabecestat in Healthy Female Participants Taking Oral Contraceptive
The study will evaluate the effect of oral contraceptive (birth control pill) on the blood level of lanabecestat when both are given together. Side effects will be monitored and documented.
- Trial name
- NCT03506399
- Testing
- Lanabecestat, Oral Contraceptive
- Where
- Singapore
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Tuberculosis
A Study to Investigate the Repeat-dose Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With Ganfeborole in Female Participants of Non-childbearing Potential
This study is designed to assess the pharmacokinetics (PK), safety, and tolerability of Ganfeborole and Microgynon, an oral contraceptive containing ethinylestradiol (EE) and levonorgestrel (LNG), when Microgynon is administered…
- Trial name
- NCT07784894
- Testing
- Ganfeborole, Microgynon
- Where
- Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline