Clinical trials: Estrogen Level
Hypertension, Hyperuricemia
Reversal of an Unfavorable Effect of Hydrochlorothiazide Compared to Angiotensin Converting Enzyme Inhibitor on Serum Uric Acid and Oxypurines Levels by Estrogen-progestin Therapy in Hypertensive Postmenopausal Women.
The aim was to assess the effect of estrogen-progestin therapy (EPT) on serum levels of uric acid (SUA) and its precursors: xanthine (X) and hypoxanthine (HX) and on uric acid (UA) renal excretion in hypertensive postmenopausal…
- Conditions
- Hypertension, Hyperuricemia, Menopause
- Trial name
- NCT03921736
- Testing
- Perindopril, Hydrochlorothiazide, Estracomb TTS
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Anna Posadzy-Małaczyńska
Estrogen, Menopause
Patient Adherence to Premarin Versus Vagifem Therapy After Female Pelvic Reconstructive Surgery
PURPOSE: To evaluate patient adherence to cream versus tablet based local estrogen therapy by randomizing treatment modalities to determine differences in adherence to either form.
- Conditions
- Estrogen, Menopause, Pelvic Floor Disorders, Surgery
- Trial name
- NCT02860897
- Testing
- Premarin, Vagifem
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Breast Cancer
The Effect of Grape Seed Extract on Estrogen Levels of Postmenopausal Women
The role of estrogens in the pathogenesis of breast cancer has been well documented. This has led to the development of "Anti-Estrogens" (selective estrogens receptor modulators and Aromatase Inhibitors), used for treatment and…
- Trial name
- NCT00566553
- Testing
- Grape Seed Extract
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Cancer
Effect of PPARγ2 Polymorphism and NSAIDs on Acute Alcohol-induced Changes in Serum Estrogens Among Post-menopausal Women
Postmenopausal women, stratified by a peroxisome proliferator-activated receptor gamma-2 (PPARG) polymorphism, were given the following treatments in a random order with a 5w wash-out period: a 400mg ibuprofen tablet or a placebo…
- Trial name
- EPPNASE (NCT02463383)
- Testing
- Ibuprofen Tab 400 MG
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Professor Lars Ove Dragsted
Low Serum Testosterone Levels in Man
D-chiro-inositol Increases Androgens and Reduces Estrogens in Human Serum
The aim of this pilot study is to test the effect of a 30 day-D-chiro-inositol oral treatment on a set of clinical parameters (mainly sex hormones) in a group of male volunteers selected by their age and BMI to investigate if…
- Trial name
- NCT04615767
- Testing
- D-chiro-inositol
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Schizophrenia, Schizophreniform
Glutamatergic Amino Acids and Oxytocin Levels in the Plasma of Patients in First Psychotic Episode (FPE)- Before and After Neuroleptic Treatment
The goal of our research is to check the levels of D-Serine, Glycine, and other Glutamatergic amino acids, in patients with First Psychotic Episode (FPE).
- Conditions
- Schizophrenia, Schizophreniform, Schizoaffective Disorder, Brief Psychotic Episode
- Trial name
- NCT00789022
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Healthy
The Effects of Red Wine and White Wine on Blood Estrogen and Progesterone Levels
Healthy pre-menopausal women will be recruited in order to test the effects of red wine and white wine on blood estrogen and progesterone levels.
- Trial name
- NCT00572351
- Testing
- Red Wine, White Wine
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Postmenopausal Atrophic Vaginitis, Genitourinary Syndrome of Menopause
Difference in Serum Estrogen Level Based on Methods of Vaginal Estrogen Application (fingertip Vs Applicator Use) in Post-menopausal Women
Study the change in serum estrogen level based on the method of vaginal cream application (applicator vs fingertip application) and Measure patient satisfaction with vaginal estrogen cream application based on the method of…
- Trial name
- NCT06808347
- Testing
- application of the vaginal estrogen cream
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Healthy
Scalp Hair Estradiol and Progesterone Level Determination in Women (Proof of Concept Study)
The investigators hypothesis is that we can determine estrogen and progesterone levels in the hair by using the immune method and we can show a significant difference in the levels of these hormones in both groups of women: pre…
- Trial name
- NCT02755038
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Skin Tear, Estrogen Deficiency
Estrogens Levels and Receptors Status and Skin Tears
Background: Skin tears (ST) or "laceration injuries" or "flap wounds" are injuries that are often found in residents of residential care facilities (RCFs).
- Trial name
- ESKITE (NCT04513405)
- Testing
- Blood sampling, Shave Biopsy
- Where
- Italy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
Menopause
A Comparison of Patch vs. Pill Estrogen Therapy on Testosterone Levels and Thyroid Tests in Menopausal Women
This study compares the effects of 12 weeks of treatment with transdermal versus oral estrogen therapy on testsoterone levels and thyroid tests in healthy, naturally menopausal women.
- Trial name
- NCT00224094
- Testing
- Premarin® (oral) vs. Alora® (transdermal)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Watson Pharmaceuticals
Vasodilation, Oral Soft Tissue Conditions
Investigation of Endothelium-dependent Vasodilation in Human Gingiva
The first aim of this study is to create a cumulative dose-response curve for acetylcholine in men (low serum estrogen levels) to determine the lowest concentration with which we can induce a maximal vasodilation effect on the…
- Trial name
- NCT06454084
- Testing
- Acetylcholine Chloride
- Where
- Hungary
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Healthy
4 mA tDCS, Estrogen, and Leg Muscle Fatigability
The majority of transcranial direct current stimulation (tDCS) studies have failed to consider sex as a modulating factor. This neglect may partly account for the high inter-subject variability bemoaned by many tDCS investigators…
- Trial name
- NCT04471805
- Testing
- Transcranial direct current stimulation 4 mA
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Breast Cancer
Studying the Effect of Freeze-Dried Table Grape Powder on Blood Estrogen Levels in Postmenopausal Women
RATIONALE: Estrogen can cause the growth of breast cancer cells. Studying samples of blood and urine in the laboratory from participants receiving freeze-dried table grape powder may help doctors understand the effect of this…
- Trial name
- NCT00611104
- Testing
- standardized freeze-dried table grape powder, laboratory biomarker analysis, pharmacological study
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Menopause, Depression
Brain Imaging Study in Menopausal Women With and Without Major Depressive Disorder
The purpose this study is to measure cortical gama-aminobutyric acid levels (GABA) levels in menopausal women with major depressive disorder and healthy subjects using nuclear magnetic resonance spectroscopy (MRS).
- Trial name
- NCT00626340
- Testing
- MDD diagnosis and Estrogen treatment, MDD diagnosis and Fluoxetine treatment, MDD diagnosis with both Estrogen and Fluoxetine treatment
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Breast Cancer
Effect of a Natural Health Product on Urinary Estrogen Metabolites
The purpose of this study is to determine if a supplemental formula can beneficially alter the ratio of urinary estrogen metabolites.
- Trial name
- NCT01089049
- Testing
- FemMED Breast Health Formula
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Healthy
Comparison of Blood Levels of Two Formulations of the Selective Hormone Receptor Modulator CDB-2914
This study will compare blood levels of the drug CDB-2914 in healthy women receiving the compound in crystalline powder form with the blood levels of women receiving an identical dose of the drug in micronized form.
- Trial name
- NCT00041899
- Testing
- CDB-2914, COB-2914
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Body Composition, Muscle Function
GLP-1RA Effects on Lean Mass and Bone Health in Midlife Women
This study is designed with the interest to learn on the effects of estrogen levels and how it affects body compositions and muscle function in midlife women who are taking a GLP-1RA for weight loss.
- Conditions
- Body Composition, Muscle Function, GLP-1, Estrogen Level
- Trial name
- GLOW (NCT07422987)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Behavioral Correlates of Estradiol
Estrogen and Cooperation, Competitiveness, and Risk Preferences
This study observes the effects of female cycle hormones on cooperation, competitiveness and risk preferences under experimental conditions. Especially, the causal effect of estradiol is isolated.
- Trial name
- FELICIA (NCT03584971)
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Psychiatric/Mood Disorder | Patient, Estrogen Receptor Levels
Validation of [18F]FES for Imaging of Brain Estrogen Receptors
Validation of [18F]-FES for imaging of estrogen receptors in the brain The primary objective of the study is to determine if [18F]-FES Positron Emission Tomography (PET) can be used to quantify the estrogen receptor expression in…
- Conditions
- Psychiatric/Mood Disorder | Patient, Estrogen Receptor Levels, Premenopausal, Postmenopausal
- Trial name
- NCT01842217
- Testing
- FES-PET
- Where
- Netherlands
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen