Clinical trials: Etiology
Urinary Bladder Neurogenic
Pharmacokinetics and Safety Study With Alfuzosin in Children and Adolescents With Elevated Detrusor Leak Point Pressure of Neuropathic Etiology
The primary objective is to investigate the pharmacokinetics (PK) of 2 doses of alfuzosin (given as a solution or tablets depending on age) in children and adolescents 2 to 16 years of age with elevated detrusor Leak Point…
- Trial name
- ALFACHIP (NCT00629720)
- Testing
- alfuzosin (SL770499)
- Where
- 2 sites in United States, Serbia
- Volunteers
- 29 people
- Sponsor
- Sanofi
Severe Acute Respiratory Syndrome Coronavirus 2
An Exploratory Study of ADR-001 in Patients with Severe Pneumonia Caused by SARS-CoV-2 Infection
Safety and efficacy of ADR-001 are evaluated in Patients with Severe Pneumonia caused by SARS-CoV-2 infection.
- Trial name
- COVID-19 (NCT04522986)
- Testing
- Mesenchymal stem cell
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Rohto Pharmaceutical Co., Ltd.
Infection
Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter
RATIONALE: Giving the antibiotic teicoplanin by infusion and allowing bacteria to be exposed to the antibiotic for a longer period of time may be effective in preventing or controlling septicemia.
- Trial name
- NCT00024453
- Testing
- teicoplanin
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 1,360 people
- Sponsor
- Children's Cancer and Leukaemia Group
ACL Injury
Causes and Patterns of Anterior Cruciate Ligament Injuries Among Egyptian Population
The aim of work is to detect the patterns and the causes of ACL injury among Egyptian population and to identify its risk factors. Identify the male to female ratio of injuries in our community.
- Trial name
- NCT03773341
- Testing
- research questionnaire
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intravascular Lithotripsy
Clinical Trial on the Treatment of Stent Underexpansion Caused by Calcification Using Intravascular Lithotripsy
Our aim is to investigate the efficacy and safety of intravascular lithotripsy(IVL) in the treatment of stent underexpansion caused by calcification through a prospective, multicenter, randomized controlled trial.
- Trial name
- NCT06521905
- Testing
- intravascular lithotripsy, high-pressure ballon
- Volunteers
- 222 people
- Sponsor
- China National Center for Cardiovascular Diseases
Diabetic Peripheral Neuropathy
Effect of an Exercise Program on Motor Dysfunctions Caused by Diabetic Peripheral Neuropathy
Diabetic Peripheral Neuropathy (DPN) affects approximately half of people with Diabetes Mellitus (DM). Its repercussions on the musculoskeletal system and biomechanics mainly impact balance and locomotor function.
- Trial name
- NCT07100301
- Testing
- Proximal/distal protocol, Distal protocol
- Volunteers
- 64 people
- Sponsor
- Federal University of Piaui
Staphylococcal Skin Infections
Safety and Efficacy of Daptomycin for the Treatment of Complicated Skin and Skin-structure Infections
This study will evaluate the safety and efficacy of daptomycin against complicated skin and skin-structure infections in adults
- Trial name
- NCT00463801
- Testing
- Daptomycin
- Where
- 2 sites in Italy
- Volunteers
- 52 people
- Sponsor
- Novartis
Kidney Transplant; Complications
Serun Fluoride and Kidney Transplant
Our primary goal is to investigate any hidden burden upon the grafted kidney from the increase of serum fluoride resulted from sevoflurane, versus isoflurane.
- Trial name
- NCT03373266
- Testing
- Sevoflurane, Isoflurane
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Neurotoxicity, Pain
Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
RATIONALE: Lamotrigine may be effective in reducing pain, numbness, tingling, and other symptoms of peripheral neuropathy. It is not yet known whether lamotrigine is effective in treating peripheral neuropathy caused by…
- Conditions
- Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00068445
- Testing
- lamotrigine
- Where
- 23 sites in United States
- Volunteers
- 131 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Helicobacter Pylori Infection, Susceptibility to
Helicobacter Pylori Infection Among Women With Recurrent Abortion of Unknown Cause
Helicobacter pylori (H. pylori) infection affects approximately one half of the world population and it is more prevalent in developing countries. This microorganism colonizes the stomach.
- Trial name
- NCT07293169
- Testing
- H pylori eradication
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Insufficiency;Cardiac, Cancer
Effect of Physical Training in Patients With Heart Failure Caused by Chemotherapy for Cancer Treatment
New therapies for cancer increased patient survival, but led to the recognition of adverse effects associated with cancer treatment, such as the use of chemotherapy.
- Conditions
- Insufficiency;Cardiac, Cancer, Cardiotoxicity, Heart Failure
- Trial name
- NCT04047901
- Testing
- exercise training
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Pulmonary Disease
Evaluation of the Causes and Disease Processes of Chronic Lung Disease
Chronic lung diseases are disorders associated with abnormalities in any of the structures involved in the process of breathing and bringing oxygen into the lungs and blood.
- Trial name
- NCT00001183
- Where
- United States
- Volunteers
- 6,564 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pneumonia
Nebulized Ceftazidime and Amikacin in Ventilator Associated Pneumonia
Pseudomonas aeruginosa is one of the major causative microorganisms of ventilator-associated pneumonia often resistant to antibiotics.
- Trial name
- NCT00786305
- Testing
- ceftazidime and amikacin
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Glaucoma, Healthy
Cause of Pigment Dispersion Syndrome
The purpose of this study is to learn how pigment is released from the iris (the colored part of the eye) in patients with pigment dispersion syndrome.
- Conditions
- Glaucoma, Healthy, Pigment Dispersion Syndrome
- Trial name
- NCT00005919
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Vascular Infection Caused by C. Burnetii
Vascular Infections Caused by Coxiella Burnetii
high morbidity and mortality. In France, Coxiella burnetii-related vascular infections appear to be increasing, though data remain limited.
- Trial name
- COXIVAS (NCT07305402)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Bordeaux
Child Development
The Effect of Early-life Risk Factors on the Etiology of Diabetes in Children: a Birth Cohort
In recent years, with the rising prevalence of obesity among children, the incidence of type 2 diabetes in children and adolescents has continued to be increased.
- Trial name
- NCT04313998
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sijia Gu
Anastomotic Leaks
Observational Analysis of the Cause of Leaks When Bowel is Cut and Reconnected
The purpose of this study is to identify the cause of leaks that sometimes occur after a section of the bowel is removed and reconnected.
- Trial name
- NCT02178228
- Where
- United States
- Volunteers
- 1,077 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ventilator Associated Pneumonia
Microbial Etiology of Ventilator-associated Pneumonia in COVID-19 Infected Patients
National multicentric observational retrospective case-control study comparing the relative frequency of the various microorganisms responsible for VAP in patients infected or not by SARS-CoV-2 and their resistance to antibiotics.
- Trial name
- NCT04344509
- Testing
- Bacterial species isolated
- Volunteers
- 10,000 people
- Sponsor
- Poitiers University Hospital
Vaginal Odor
Efficacy of (WaterWorks®)Douching Device for Elimination of Perceived Vaginal Odor Not Caused by BV or Vaginitis
Comparing the new Stainless Steel WaterWorks® douching device to a commercially available douching device using just water for safety and efficacy of odor abatement.
- Trial name
- NCT00417365
- Testing
- WaterWorks Douching Device
- Where
- 7 sites in United States
- Volunteers
- 100 people
- Sponsor
- Abbott Research Group
Overactive Bladder Syndrome, Enuresis, Nocturnal
Overactive Bladder Syndrome
Purpose: A lot of etiological factors related to overactive bladder (OAB) has been investigated. However, the role of primary nocturnal enuresis (NE), which is characterized with childhood night time incontinence, in the etiology…
- Trial name
- NCT05151081
- Testing
- basicly
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Hisar Intercontinental Hospital
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